Faculty Opinions recommendation of Architecture of a catalytically active homotrimeric plant cellulose synthase complex.

2020 ◽  
Author(s):  
Zhaosheng Kong
Keyword(s):  
Cellulose Synthase ◽  
Catalytically Active ◽  
Cellulose Synthase Complex

scholarly journals Architecture of a catalytically active homotrimeric plant cellulose synthase complex

Science ◽  
2020 ◽  
Vol 369 (6507) ◽  
pp. 1089-1094 ◽  
Author(s):  
Pallinti Purushotham ◽  
Ruoya Ho ◽  
Jochen Zimmer
Keyword(s):  
Cell Wall ◽  
Plant Cell ◽  
Molecular Basis ◽  
Plant Cell Wall ◽  
Cellulose Synthase ◽  
Exit Point ◽  
Transmembrane Segments ◽  
Catalytically Active ◽  
Cellulose Synthase Complex ◽  
Microfibril Formation

Cellulose is an essential plant cell wall component and represents the most abundant biopolymer on Earth. Supramolecular plant cellulose synthase complexes organize multiple linear glucose polymers into microfibrils as load-bearing wall components. We determined the structure of a poplar cellulose synthase CesA homotrimer that suggests a molecular basis for cellulose microfibril formation. This complex, stabilized by cytosolic plant-conserved regions and helical exchange within the transmembrane segments, forms three channels occupied by nascent cellulose polymers. Secretion steers the polymers toward a common exit point, which could facilitate protofibril formation. CesA’s N-terminal domains assemble into a cytosolic stalk that interacts with a microtubule-tethering protein and may thus be involved in CesA localization. Our data suggest how cellulose synthase complexes assemble and provide the molecular basis for plant cell wall engineering.

scholarly journals The Arabidopsis Cellulose Synthase Complex: A Proposed Hexamer of CESA Trimers in an Equimolar Stoichiometry

2014 ◽  
Vol 26 (12) ◽  
pp. 4834-4842 ◽  
Author(s):  
Joseph L. Hill ◽  
Mustafa B. Hammudi ◽  
Ming Tien
Keyword(s):  
Cellulose Synthase ◽  
Cellulose Synthase Complex

scholarly journals S-Acylation of the cellulose synthase complex is essential for its plasma membrane localization

Science ◽  
2016 ◽  
Vol 353 (6295) ◽  
pp. 166-169 ◽  
Author(s):  
M. Kumar ◽  
R. Wightman ◽  
I. Atanassov ◽  
A. Gupta ◽  
C. H. Hurst ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Cellulose Synthase ◽  
Membrane Localization ◽  
Plasma Membrane Localization ◽  
Cellulose Synthase Complex

scholarly journals Control of Cellulose Synthase Complex Localization in Developing Xylem

2003 ◽  
Vol 15 (8) ◽  
pp. 1740-1748 ◽  
Author(s):  
John C. Gardiner ◽  
Neil G. Taylor ◽  
Simon R. Turner
Keyword(s):  
Cellulose Synthase ◽  
Cellulose Synthase Complex

scholarly journals Trafficking of the Plant Cellulose Synthase Complex

2010 ◽  
Vol 153 (2) ◽  
pp. 427-432 ◽  
Author(s):  
Raymond Wightman ◽  
Simon Turner
Keyword(s):  
Cellulose Synthase ◽  
Cellulose Synthase Complex

scholarly journals AcsA–AcsB: The core of the cellulose synthase complex from Gluconacetobacter hansenii ATCC23769

2016 ◽  
Vol 82 ◽  
pp. 58-65 ◽  
Author(s):  
John B. McManus ◽  
Ying Deng ◽  
Nivedita Nagachar ◽  
Teh-hui Kao ◽  
Ming Tien
Keyword(s):  
Cellulose Synthase ◽  
Gluconacetobacter Hansenii ◽  
The Core ◽  
Cellulose Synthase Complex

scholarly journals BRASSINOSTEROID INSENSITIVE2 negatively regulates cellulose synthesis in Arabidopsis by phosphorylating cellulose synthase 1

2017 ◽  
Vol 114 (13) ◽  
pp. 3533-3538 ◽  
Author(s):  
Clara Sánchez-Rodríguez ◽  
KassaDee Ketelaar ◽  
Rene Schneider ◽  
Jose A. Villalobos ◽  
Chris R. Somerville ◽  
...  
Keyword(s):  
Phosphorylation Site ◽  
Point Mutations ◽  
Cellulose Synthase ◽  
Negative Regulator ◽  
Primary Cell Wall ◽  
Cellulose Synthesis ◽  
Cellulose Biosynthesis ◽  
Plant Growth And Development ◽  
Cellulose Synthase Complex ◽  
A Subunit

The deposition of cellulose is a defining aspect of plant growth and development, but regulation of this process is poorly understood. Here, we demonstrate that the protein kinase BRASSINOSTEROID INSENSITIVE2 (BIN2), a key negative regulator of brassinosteroid (BR) signaling, can phosphorylate Arabidopsis cellulose synthase A1 (CESA1), a subunit of the primary cell wall cellulose synthase complex, and thereby negatively regulate cellulose biosynthesis. Accordingly, point mutations of the BIN2-mediated CESA1 phosphorylation site abolished BIN2-dependent regulation of cellulose synthase activity. Hence, we have uncovered a mechanism for how BR signaling can modulate cellulose synthesis in plants.

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