scholarly journals Faculty Opinions recommendation of Sensitive protein alignments at tree-of-life scale using DIAMOND.

Author(s):  
Patrice Koehl
2021 ◽  
Vol 18 (4) ◽  
pp. 366-368
Author(s):  
Benjamin Buchfink ◽  
Klaus Reuter ◽  
Hajk-Georg Drost

AbstractWe are at the beginning of a genomic revolution in which all known species are planned to be sequenced. Accessing such data for comparative analyses is crucial in this new age of data-driven biology. Here, we introduce an improved version of DIAMOND that greatly exceeds previous search performances and harnesses supercomputing to perform tree-of-life scale protein alignments in hours, while matching the sensitivity of the gold standard BLASTP.


2011 ◽  
Vol 27 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Heide Glaesmer ◽  
Gesine Grande ◽  
Elmar Braehler ◽  
Marcus Roth

The Satisfaction with Life Scale (SWLS) is the most commonly used measure for life satisfaction. Although there are numerous studies confirming factorial validity, most studies on dimensionality are based on small samples. A controversial debate continues on the factorial invariance across different subgroups. The present study aimed to test psychometric properties, factorial structure, factorial invariance across age and gender, and to deliver population-based norms for the German general population from a large cross-sectional sample of 2519 subjects. Confirmatory factor analyses supported that the scale is one-factorial, even though indications of inhomogeneity of the scale have been detected. Both findings show invariance across the seven age groups and both genders. As indicators of the convergent validity, a positive correlation with social support and negative correlation with depressiveness was shown. Population-based norms are provided to support the application in the context of individual diagnostics.


2019 ◽  
Vol 35 (4) ◽  
pp. 555-563 ◽  
Author(s):  
Veljko Jovanović

Abstract. The present research aimed at examining measurement invariance of the Serbian version of the Satisfaction with Life Scale (SWLS) across age, gender, and time. A total sample in Study 1 consisted of 2,595 participants from Serbia, with a mean age of 23.79 years (age range: 14–55 years). The final sample in Study 2 included 333 Serbian undergraduate students ( Mage = 20.81; age range: 20–27 years), who completed the SWLS over periods of 6 and 18 months after the initial assessment. Confirmatory factor analysis (CFA) supported the modified unidimensional model of the SWLS, with correlated residuals of items 4 and 5 tapping past satisfaction. The results of the multigroup confirmatory factor analysis supported the full scalar invariance across gender and over time and partial scalar invariance across age. Latent mean comparisons revealed that women reported higher life satisfaction than men. Additionally, adolescents reported higher life satisfaction than students and adults, with adults showing the lowest life satisfaction. Our findings indicate that the SWLS allows meaningful comparisons in life satisfaction across age, gender, and over time.


2018 ◽  
Vol 30 (9) ◽  
pp. 1261-1266 ◽  
Author(s):  
Martin Guhn ◽  
Tavinder K. Ark ◽  
Scott D. Emerson ◽  
Kimberly A. Schonert-Reichl ◽  
Anne M. Gadermann

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