Faculty Opinions recommendation of Sentinel lymph node biopsy accurately stages the regional lymph nodes for T1-T2 oral squamous cell carcinomas: results of a prospective multi-institutional trial.

Introduction: Concept of sentinel lymph node biopsy has been discussed during several last decades, because this idea seems perspective in terms of modern minimally invasive and organ-preserving era. However, this method has several limitations including complicated anatomy of gastric lymph nodes distribution and presence of skip-metastases. Materials and methods: 66 Patients with early gastric cancer, intermediate risk of lymph node metastases and technical possibility of ESD were included into our investigation. Patients were assigned to either ESD with sentinel lymph node biopsy (54 patients), or underwent distal gastrectomy or total gastrectomy with D1+/D2 lymphadenectomy (12 patients) by chance. Results: 56 (84,6%) Patients had at least one sentinel lymph node. 11 (16,7%) Patients with T1a-T1b had metastases in regional lymph nodes, 9 of them in sentinel lymph nodes (2 false-negative result). So, we calculated sensitivity of 84,6%. In one case, the metastasis was located outside the sentinel lymphatic basin, and in the other case, metastasis was detected in a patient with unlit lymph nodes. Conclusion: Today sentinel lymph node biopsy thechnique is considered as a well investigated and widly used method. The concept itself is promising for organ-preserving gastric cancer surgery.

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Sentinel lymph node biopsy in T1/T2 squamous cell carcinomas of the tongue: A prospective study

Oncology Letters ◽

10.3892/ol.2015.3933 ◽

2015 ◽

Vol 11 (1) ◽

pp. 600-604 ◽

Cited By ~ 14

Author(s):

KEYVAN SAGHEB ◽

KAWE SAGHEB ◽

ROMAN RAHIMI-NEDJAT ◽

KATHY TAYLOR ◽

BILAL AL-NAWAS ◽

...

Keyword(s):

Lymph Node ◽

Sentinel Lymph Node ◽

Sentinel Lymph Node Biopsy ◽

Prospective Study ◽

Squamous Cell ◽

Lymph Node Biopsy ◽

Squamous Cell Carcinomas ◽

Node Biopsy ◽

A Prospective Study

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838: Evaluation of Dynamic Lymphoscintigraphy and Sentinel Lymph Node Biopsy for the Detection of Occult Metastases in Patients with Penile Squamous Cell Carcinoma

The Journal of Urology ◽

10.1016/s0022-5347(18)31078-4 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 279-280 ◽

Cited By ~ 1

Author(s):

Paul Hadway ◽

Yuko Smith ◽

Ben Hughes ◽

Cathy M. Corbishley ◽

Susan Heenan ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Lymph Node ◽

Sentinel Lymph Node ◽

Sentinel Lymph Node Biopsy ◽

Cell Carcinoma ◽

Squamous Cell ◽

Lymph Node Biopsy ◽

Occult Metastases ◽

Node Biopsy ◽

Penile Squamous Cell Carcinoma

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Faculty Opinions recommendation of Staging for cutaneous squamous cell carcinoma as a predictor of sentinel lymph node biopsy results: meta-analysis of American Joint Committee on Cancer criteria and a proposed alternative system.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718234424.793489836 ◽

2014 ◽

Author(s):

Murad Alam ◽

Kira Minkis

Keyword(s):

Squamous Cell Carcinoma ◽

Lymph Node ◽

Sentinel Lymph Node ◽

Sentinel Lymph Node Biopsy ◽

Cell Carcinoma ◽

Squamous Cell ◽

Meta Analysis ◽

Lymph Node Biopsy ◽

Cutaneous Squamous Cell Carcinoma ◽

Node Biopsy

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Cytologic Features of Lipogranulomatous Reaction in an Axillary Sentinel Lymph Node

Acta Cytologica ◽

10.1159/000513982 ◽

2021 ◽

pp. 1-4

Author(s):

Jose Antonio Jimenez-Heffernan ◽

Mariel Valdivia-Mazeyra ◽

Patricia Muñoz-Hernández ◽

Consuelo López-Elzaurdia

Keyword(s):

Lymph Node ◽

Sentinel Lymph Node ◽

Sentinel Lymph Node Biopsy ◽

Lymph Nodes ◽

Breast Biopsy ◽

Lymph Node Biopsy ◽

Sentinel Lymph Nodes ◽

Fat Necrosis ◽

Histologic Analysis ◽

Node Biopsy

Introduction: Multinucleated giant cells (MGC) are a rare finding when evaluating axillary sentinel lymph nodes. Some are described as foreign body-type MGC accompanied by foamy macrophages. They have been rarely reported in nodes from patients in which a previous breast biopsy was performed. The tissue damage induced by biopsy results in secondary changes including fat necrosis and hemorrhage that can migrate to axillary nodes. In this report, we illustrate a lipogranulomatous reaction in cytologic samples obtained during a sentinel lymph node examination of a woman previously biopsied because of breast carcinoma. We have found no previous cytologic descriptions and consider it an interesting finding that should be known to avoid diagnostic misinterpretations. Case: A 51-year-old woman underwent mastectomy of the right breast with a sentinel lymph node biopsy at our medical center. One month before, a control mammography revealed suspicious microcalcifications and a vacuum-assisted breast biopsy resulted in a diagnosis of high-grade intraductal carcinoma with comedonecrosis. Surgery with a sentinel lymph node biopsy was performed. The sentinel node was processed as an intraoperative consultation. Frozen sections and air-dried Diff-Quik stained samples were obtained. They showed abundant lymphocytes with MGC and tumoral cells. MGC showed ample cytoplasm with evident vacuoles of variable size. Occasional hemosiderin-laden macrophages were also present. The complete histologic analysis and immunohistochemical studies revealed no malignant cells. Histologic analysis showed, in subcapsular location, occasional MGC phagocyting lipid droplets. Hemosiderin-laden macrophages were a common finding. Conclusion: Lipogranulomas may appear at axillary sentinel lymph nodes because of fat necrosis induced by previous breast biopsy. The most important consideration is not confounding MGC with epithelial cell clusters. This can occur with not well-processed samples, especially if unmounted.

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