Which is the Pharmacodynamic Target to Calculate a Rational Dose against SARS-Cov-2?

Latin american journal of clinical sciences and medical technology ◽

10.34141/ljcs5523822 ◽

2020 ◽

Vol 2 (2) ◽

pp. 35-37 ◽

Author(s):

Andres F. Zuluaga ◽

Carlos A. Rodriguez ◽

Maria A. Montoya-Giraldo

Keyword(s):

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Abstract 1169: Rational dose and schedule selection for the combination of paclitaxel and the investigational agent alisertib in recurrent ovarian cancer: optimization of therapeutic index based on translational hematological toxicity and exposure-efficacy modeling.

10.1158/1538-7445.am2013-1169 ◽

2013 ◽

Author(s):

Jeffrey Ecsedy ◽

Xiaofei Zhou ◽

Jay Mettetal ◽

Mengkun Zhang ◽

Arijit Chakravarty ◽

...

Keyword(s):

Ovarian Cancer ◽

Therapeutic Index ◽

Recurrent Ovarian Cancer ◽

Hematological Toxicity ◽

Investigational Agent ◽

Rational Dose ◽

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Biomarker exposure-response relationships as the basis for rational dose selection: Lessons from a simulation exercise using a selective COX-2 inhibitor

The Journal of Clinical Pharmacology ◽

10.1002/jcph.629 ◽

2015 ◽

Vol 56 (5) ◽

pp. 609-621 ◽

Author(s):

Amit Taneja ◽

Sean P. Oosterholt ◽

Meindert Danhof ◽

Oscar Della Pasqua

Keyword(s):

Dose Selection ◽

Simulation Exercise ◽

Exposure Response ◽

Rational Dose ◽

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Study of the rational dose of propofol in elderly patients under bispectral index monitoring during total intravenous anesthesia

Medicine ◽

10.1097/md.0000000000019043 ◽

2020 ◽

Vol 99 (5) ◽

pp. e19043

Author(s):

Lina Jia ◽

Jiachen Hou ◽

Haibo Zheng ◽

Lihua Sun ◽

Yingying Fan ◽

...

Keyword(s):

Elderly Patients ◽

Bispectral Index ◽

Total Intravenous Anesthesia ◽

Intravenous Anesthesia ◽

Bispectral Index Monitoring ◽

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Abstract 791: Rational dose optimization for multi-drug cocktails

10.1158/1538-7445.am2014-791 ◽

2014 ◽

Author(s):

Christopher J. Zopf ◽

Andrew Chen ◽

Santhosh Palani ◽

Rachael Brake ◽

Mark Manfredi ◽

...

Keyword(s):

Dose Optimization ◽

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Clinical Application of Pharmacokinetics: Basis for Rational Dose Selection in a Critically Ill Patient on Renal Replacement Therapy

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/s13318-018-0524-4 ◽

2018 ◽

Vol 44 (3) ◽

pp. 433-436

Author(s):

Slobodan M. Janković

Keyword(s):

Renal Replacement Therapy ◽

Replacement Therapy ◽

Critically Ill ◽

Clinical Application ◽

Critically Ill Patient ◽

Dose Selection ◽

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Pecularities of Composite Lacto- and Bifidoprobiotic Biotechnology: Determination of Rational Dose Influence upon Chicken Broilers’ Performance

Research Bulletin of the National Technical University of Ukraine Kyiv Politechnic Institute ◽

10.20535/1810-0546.2017.3.104550 ◽

2017 ◽

Vol 0 (3) ◽

pp. 12-18

Author(s):

Svitlana Garda ◽

Svitlana Danylenko ◽

Taisa Ryzhkova ◽

Grygorii Litvinov

Keyword(s):

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The pharmacokinetics and toxicity of the anthrapyrazole anti-cancer drug CI-941 in the mouse: a guide for rational dose escalation in patients

Cancer Chemotherapy and Pharmacology ◽

10.1007/bf00258450 ◽

1989 ◽

Vol 23 (1) ◽

Author(s):

MartinA. Graham ◽

DavidR. Newell ◽

BrendaJ. Foster ◽

A.Hilary Calvert

Keyword(s):

Dose Escalation ◽

Cancer Drug ◽

Anti Cancer ◽

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A Pilot/Phase II Study of Stereotactic Radiosurgery for Brain Metastases Using Rational Dose Selection

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2018.07.1113 ◽

2018 ◽

Vol 102 (3) ◽

pp. e372-e373

Author(s):

J.B. Yu ◽

C. Singh ◽

R.S. Bindra ◽

J.N. Contessa ◽

Z.A. Husain ◽

...

Keyword(s):

Brain Metastases ◽

Stereotactic Radiosurgery ◽

Phase Ii ◽

Phase Ii Study ◽

Pilot Phase ◽

Dose Selection ◽

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Reducing Palivizumab Dose Requirements Through Rational Dose Regimen Design

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12364 ◽

2018 ◽

Vol 8 (1) ◽

pp. 26-33

Author(s):

Stephanie E. Reuter ◽

Allan M. Evans ◽

Michael B. Ward

Keyword(s):

Dose Regimen ◽

Rational Dose ◽

Dose Regimen Design

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Integrated Quantitation of Biotherapeutic Drug-Target Binding, Biomarkers, and Clinical Response to Support Rational Dose Regimen Selection

Pharmaceutical Sciences Encyclopedia ◽

10.1002/9780470571224.pse548 ◽

2015 ◽

pp. 1-21 ◽

Author(s):

Philip J. Lowe ◽

Anne Kümmel ◽

Christina Vasalou ◽

Soichiro Matsushima ◽

Andrej Skerjanec

Keyword(s):

Clinical Response ◽

Dose Regimen ◽

Drug Target ◽

Rational Dose ◽

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