scholarly journals Correlação entre a porcentagem de glóbulos vermelhos, teor de hemoglobina e saturação de oxigênio tecidual em cães anêmicos / Correlation between the percentage of red bood cells, hemoglobina contente and tissue oxygen saturation in anemic dogs

2021 ◽  
Vol 4 (4) ◽  
pp. 6309-6319
Author(s):  
Guilherme Costa Paião ◽  
Thainá Pires dos Santos Sauniti ◽  
Bianca Fonseca dos Santos ◽  
Laís Orsi Vieira ◽  
Rômulo Francis Estangari Lot

As células vermelhas também chamadas (hemácias, eritrócitos, glóbulos vermelhos), são as células mais numerosas nos mamíferos, possuem um formato bicôncavo, e tem como função o transportam oxigênio (O₂), dióxido de carbono (CO₂), assim como, transporte e tamponamento de íons hidrogênio (Hᶧ). A hemoglobina é uma proteína globular responsável por carrear o oxigênio pelo organismo, isto só é possível devido a sua estrutura ser capaz de fazer a ligação com a molécula de oxigênio e carrear ela até aos tecidos, sabendo se que a quantidade diminuída de glóbulos vermelhos no sangue, consequentemente diminui  quantidade de hemoglobina e por um efeito coordenado se diminui a oferta de oxigênio para os tecidos (hipóxia), a diminuição de oferta de oxigênio para os tecidos pode causar danos celulares que podem se tornar irreversíveis. O presente estudo tem como objetivo avaliar os caninos com eritrócitos baixo, analisando a concentração de hemoglobina e através de uma correlação indicar o nível para indicar uma transfusão sanguínea, afim de minimizar os danos causados pela hipóxia no organismo.

2020 ◽  
Vol 8 (2) ◽  
pp. e001815
Author(s):  
Grant A Murphy ◽  
Rajinder P Singh-Moon ◽  
Amaan Mazhar ◽  
David J Cuccia ◽  
Vincent L Rowe ◽  
...  

IntroductionThe use of non-invasive vascular and perfusion diagnostics are an important part of assessing lower extremity ulceration and amputation risk in patients with diabetes mellitus. Methods for detecting impaired microvascular vasodilatory function in patients with diabetes may have the potential to identify sites at risk of ulceration prior to clinically identifiable signs. Spatial frequency domain imaging (SFDI) uses patterned near-infrared and visible light spectroscopy to determine tissue oxygen saturation and hemoglobin distribution within the superficial and deep dermis, showing distinct microcirculatory and oxygenation changes that occur prior to neuropathic and neuroischemic ulceration.Research designs and methods35 patients with diabetes mellitus and a history of diabetic foot ulceration were recruited for monthly imaging with SFDI. Two patients who ulcerated during the year-long longitudinal study were selected for presentation of their clinical course alongside the dermal microcirculation biomarkers from SFDI.ResultsPatient 1 developed a neuropathic ulcer portended by a focal increase in tissue oxygen saturation and decrease in superficial papillary hemoglobin concentration 3 months prior. Patient 2 developed bilateral neuroischemic ulcers showing decreased tissue oxygen saturation and increased superficial papillary and deep dermal reticular hemoglobin concentrations.ConclusionsWounds of different etiology show unique dermal microcirculatory changes prior to gross ulceration. Before predictive models can be developed from SFDI, biomarker data must be correlated with the clinical course of patients who ulcerate while being followed longitudinally.Trial registration numberNCT03341559.


Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 1) ◽  
pp. P239
Author(s):  
R Kopp ◽  
S Rex ◽  
K Dommann ◽  
G Schälte ◽  
G Dohmen ◽  
...  

2016 ◽  
Vol 36 (3) ◽  
pp. 12-70 ◽  
Author(s):  
Cathy Mitchell

Hypoperfusion is the most common event preceding the onset of multiple organ dysfunction syndrome during trauma resuscitation. Detecting subtle changes in perfusion is crucial to ensure adequate tissue oxygenation and perfusion. Traditional methods of detecting physiological changes include measurements of blood pressure, heart rate, urine output, serum levels of lactate, mixed venous oxygen saturation, and central venous oxygen saturation. Continuous noninvasive monitoring of tissue oxygen saturation in muscle has the potential to indicate severity of shock, detect occult hypoperfusion, guide resuscitation, and be predictive of the need for interventions to prevent multiple organ dysfunction syndrome. Tissue oxygen saturation is being used in emergency departments, trauma rooms, operating rooms, and emergency medical services. Tissue oxygen saturation technology is just as effective as mixed venous oxygen saturation, central venous oxygen saturation, serum lactate, and Stewart approach with strong ion gap, yet tissue oxygen saturation assessment is also a direct, noninvasive microcirculatory measurement of oxygen saturation.


2019 ◽  
Vol 2019 ◽  
pp. 1-16 ◽  
Author(s):  
Min Hao ◽  
Guangyuan Liu ◽  
Anu Gokhale ◽  
Ya Xu ◽  
Rui Chen

Hyperspectral imaging (HSI) technology can be used to detect human emotions based on the power of material discrimination from their faces. In this paper, HSI is used to remotely sense and distinguish blood chromophores in facial tissues and acquire an evaluation indicator (tissue oxygen saturation, StO2) using an optical absorption model. This study explored facial analysis while people were showing spontaneous expressions of happiness during social interaction. Happiness, as a psychological emotion, has been shown to be strongly linked to other activities such as physiological reaction and facial expression. Moreover, facial expression as a communicative motor behavior likely arises from musculoskeletal anatomy, neuromuscular activity, and individual personality. This paper quantified the neuromotor movements of tissues surrounding some regions of interest (ROIs) on smiling happily. Next, we selected six regions—the forehead, eye, nose, cheek, mouth, and chin—according to a facial action coding system (FACS). Nineteen segments were subsequently partitioned from the above ROIs. The affective data (StO2) of 23 young adults were acquired by HSI while the participants expressed emotions (calm or happy), and these were used to compare the significant differences in the variations of StO2 between the different ROIs through repeated measures analysis of variance. Results demonstrate that happiness causes different distributions in the variations of StO2 for the above ROIs; these are explained in depth in the article. This study establishes that facial tissue oxygen saturation is a valid and reliable physiological indicator of happiness and merits further research.


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