scholarly journals Predictive value of tissue oxygen saturation upon mortality in Emergency Department patients with sepsis

Critical Care ◽  
2011 ◽  
Vol 15 (S1) ◽  
Author(s):  
C Vorwerk ◽  
T Coats
Keyword(s):  
Emergency Department ◽  
Oxygen Saturation ◽  
Predictive Value ◽  
Tissue Oxygen Saturation ◽  
Tissue Oxygen ◽  
Emergency Department Patients

Soft tissue oxygen saturation to predict admission from the emergency department: A prospective observational study

2017 ◽  
Vol 35 (8) ◽  
pp. 1111-1117 ◽  
Author(s):  
William T. Davis ◽  
Josh Lospinso ◽  
Robert M. Barnwell ◽  
John Hughes ◽  
Steven G. Schauer ◽  
...  
Keyword(s):  
Emergency Department ◽  
Soft Tissue ◽  
Observational Study ◽  
Oxygen Saturation ◽  
Prospective Observational Study ◽  
Tissue Oxygen Saturation ◽  
Tissue Oxygen

Tissue Oxygen Saturation Predicts the Need for Early Blood Transfusion in Trauma Patients

2008 ◽  
Vol 74 (10) ◽  
pp. 1006-1011 ◽  
Author(s):  
Jennifer Smith ◽  
Scott Bricker ◽  
Brant Putnam
Keyword(s):  
Blood Transfusion ◽  
Oxygen Saturation ◽  
Hemorrhagic Shock ◽  
Predictive Value ◽  
Near Infrared ◽  
Demographic Data ◽  
Tissue Oxygen Saturation ◽  
Trauma Patients ◽  
Tissue Oxygen ◽  
Convenience Sample

Near-infrared spectroscopy (NIRS) has been used to measure regional tissue oxygen saturation (StO2) in skeletal muscle as an indicator of perfusion in trauma patients. In an effort to prospectively examine the usefulness of StO2 in identifying trauma patients in hemorrhagic shock, we evaluated the need for blood transfusion within 24 hours of injury as a marker of significant hemorrhage. A 6-month prospective, observational study was conducted at a university-affiliated, urban Level I trauma center using a convenience sample of 26 trauma patients thought to be at high risk for hemorrhagic shock. Baseline demographic data, vital signs, laboratory values, and amounts of fluid and blood products administered were collected. NIRS-derived StO2 values were measured for 1 hour after arrival to the trauma bay and the minimum value noted. A minimum StO2 less than 70 per cent correlated with the need for blood transfusion with a sensitivity of 88 per cent and a specificity of 78 per cent. The positive predictive value was 64 per cent and the negative predictive value was 93 per cent. The need for blood transfusion within 24 hours of arrival was not predicted by hypotension, tachycardia, arterial lactate, base deficit, or hemoglobin. StO2 may represent an important screening tool for identifying trauma patients who require blood transfusion or other limited medical resources.

scholarly journals Quantifying dermal microcirculatory changes of neuropathic and neuroischemic diabetic foot ulcers using spatial frequency domain imaging: a shade of things to come?

2020 ◽  
Vol 8 (2) ◽  
pp. e001815
Author(s):  
Grant A Murphy ◽  
Rajinder P Singh-Moon ◽  
Amaan Mazhar ◽  
David J Cuccia ◽  
Vincent L Rowe ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Spatial Frequency ◽  
Oxygen Saturation ◽  
Diabetic Foot ◽  
Clinical Course ◽  
Tissue Oxygen Saturation ◽  
Tissue Oxygen ◽  
Spatial Frequency Domain Imaging ◽  
Patients With Diabetes ◽  
Spatial Frequency Domain

IntroductionThe use of non-invasive vascular and perfusion diagnostics are an important part of assessing lower extremity ulceration and amputation risk in patients with diabetes mellitus. Methods for detecting impaired microvascular vasodilatory function in patients with diabetes may have the potential to identify sites at risk of ulceration prior to clinically identifiable signs. Spatial frequency domain imaging (SFDI) uses patterned near-infrared and visible light spectroscopy to determine tissue oxygen saturation and hemoglobin distribution within the superficial and deep dermis, showing distinct microcirculatory and oxygenation changes that occur prior to neuropathic and neuroischemic ulceration.Research designs and methods35 patients with diabetes mellitus and a history of diabetic foot ulceration were recruited for monthly imaging with SFDI. Two patients who ulcerated during the year-long longitudinal study were selected for presentation of their clinical course alongside the dermal microcirculation biomarkers from SFDI.ResultsPatient 1 developed a neuropathic ulcer portended by a focal increase in tissue oxygen saturation and decrease in superficial papillary hemoglobin concentration 3 months prior. Patient 2 developed bilateral neuroischemic ulcers showing decreased tissue oxygen saturation and increased superficial papillary and deep dermal reticular hemoglobin concentrations.ConclusionsWounds of different etiology show unique dermal microcirculatory changes prior to gross ulceration. Before predictive models can be developed from SFDI, biomarker data must be correlated with the clinical course of patients who ulcerate while being followed longitudinally.Trial registration numberNCT03341559.

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