Анализ отдаленной эффективности противовирусных препаратов прямого действия в терапии хронического вирусного гепатита С

2020 ◽  
pp. 14-17
Keyword(s):  
Hepatitis C ◽  
Viral Hepatitis ◽  
High Efficiency ◽  
Chronic Viral Hepatitis ◽  
Direct Acting Antiviral ◽  
Treatment Regimens ◽  
Viral Hepatitis C ◽  
Direct Acting ◽  
And Control ◽  
Chronic Viral Hepatitis C

Long-term efficacy of direct-acting antiviral drugs (DAAD) was evaluated in 44 patients with chronic viral hepatitis C who had been receiving therapy at the Khabarovsk and Kamchatka centers for the prevention and control of AIDS and infectious diseases from 2015 to 2018. The data were evaluated through a retrospective analysis of ambulatory patient records and control in the form of a qualitative detection of viral RNA by a highly sensitive PCR method. According to the results of the analysis, 41 out of 44 patients (93,18 %) managed to achieve a stable virological response (SVR 24), which remains stable at present (p<0,05). Three of the studied patients had a relapse, probably associated with incorrect treatment regimens and the presence of cogenotypes. The data obtained indicate a high efficiency of DAAD in the treatment of chronic viral hepatitis C in the Khabarovsk and Kamchatka territories.

scholarly journals Treatment of chronic viral hepatitis C with direct acting antiviral agent: review

2019 ◽  
Vol 91 (11) ◽  
pp. 86-89
Author(s):  
V A Malov ◽  
E A Ubeeva ◽  
I P Ubeeva ◽  
S M Nikolaev ◽  
K T Umbetova
Keyword(s):  
Antiviral Agent ◽  
Chronic Viral Hepatitis ◽  
Hcv Treatment ◽  
Direct Acting Antiviral ◽  
Treatment Regimens ◽  
Infection Treatment ◽  
Viral Hepatitis C ◽  
Substantial Progress ◽  
Direct Acting ◽  
Chronic Viral Hepatitis C

HCV infection treatment regimens are viewed from positions of HCV life cycle and replication, effects of NS3/4A protease inhibitors and NS5A/NS5B inhibitors on HCV strain replication. Evolution of HCV treatment regimens from its discovery to modern DAA agents had led to substantial progress although drug resistance poses a new issue to be addressed.

scholarly journals Effectiveness of Treatment of Chronic Viral Hepatitis C by Direct-Acting Antivirals in Togo

2019 ◽  
Vol 09 (07) ◽  
pp. 125-133
Author(s):  
Laté Mawuli Lawson-Ananissoh ◽  
Aklesso Bagny ◽  
Oumboma Bouglouga ◽  
Laconi Kaaga ◽  
Rafiou El-Hadji Yakoubou ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Direct Acting Antivirals ◽  
Viral Hepatitis C ◽  
Direct Acting ◽  
Chronic Viral Hepatitis C

scholarly journals Assessment of adherence to chronic viral hepatitis C treatment in Romania: an open, single center, prospective study

2016 ◽  
Vol 2 (2) ◽  
pp. 59-68
Author(s):  
Anca Streinu-Cercel ◽  
Maria-Magdalena Moțoi ◽  
Alina Cristina Neguț ◽  
Luminița Bradu ◽  
Daniela Manolache ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Prospective Study ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Single Center ◽  
Hepatitis C Treatment ◽  
Viral Hepatitis C ◽  
Chronic Viral Hepatitis C

Epidemiological, demographic and clinical data on chronic viral hepatitis C in Tuscany

2018 ◽  
Vol 35 (4) ◽  
pp. 661-666 ◽  
Author(s):  
Cristina Stasi ◽  
Caterina Silvestri ◽  
Roberto Berni ◽  
Maurizia Rossana Brunetto ◽  
Anna Linda Zignego ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Viral Hepatitis ◽  
Clinical Data ◽  
Chronic Viral Hepatitis ◽  
Viral Hepatitis C ◽  
Chronic Viral Hepatitis C
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