scholarly journals Graft Tulang Alveolar dan Pemberian Terapi Oksigen Hiperbarik pada Gnatoschizis: Laporan Kasus

e-CliniC ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 550
Author(s):  
Nidia Limarga ◽  
Mendy Hatibie ◽  
Maximillian Ch. Oley

Abstract: Gnatoschizis is a congenital disorder due to complex causes involving many genetic and environmental factors. The shape and complexity of the cleft varies greatly, which will determine the final outcome of the reconstruction. The management involves a multidisciplinary approach including orthodontics, prosthodontics, as well as speech and psychological therapist. Bone grafting materials such as iliac crest (corticocancellous autogenous), bone morphogenetic proteins and recombinant human proteins have shown good long-term results. An additional method that is considered effective in accelerating bone growth is the administration of hyperbaric oxygen therapy (HBOT) which has been reported to increase the accumulation of minerals needed for osteogenesis, such as calcium, magnesium, and phosphorous. We reported a case of a 14-year-old girl with gnatoschizis who underwent an alveolar bone graft surgery and one day after the operation was immediately followed by administration of (HBOT) to improve the bone healing process. cleft location. Autogenous iliac bone graft was used for closure of the bony defect at the site of the cleft. Follow up at day-14 showed a satisfying result. In conclusion, in this patient continuity of upper dental arch was achieved as well as optimal alar basis, no fistula, stabile upper dental arch for orthodontic treatment, and ideal alveolar morphology that supported the ultimate goal of cleft palate treatment - improvement of quality of life.Keywords: gnatoschizis; alveolar bone graft; hyperbaric oxygen therapy  Abstrak: Gnatoschizis merupakan kelainan kongenital dengan penyebab kompleks yang meli-batkan banyak faktor genetik dan lingkungan. Bentuk dan kompleksitas sumbing sangat bervariasi, yang akan menentukan hasil akhir rekonstruksi. Tatalaksananya melibatkan pendekatan multi-disiplin termasuk ortodontik, prostodontik, serta terapi wicara dan psikologis. Bahan pencang-kokan tulang seperti krista iliaka (corticocancellous autogenous), protein morfogenetik tulang dan protein manusia rekombinan telah menunjukkan hasil jangka panjang yang baik. Salah satu metode tambahan yang dianggap efektif mempercepat pertumbuhan tulang ialah pemberian terapi oksigen hiperbarik (TOHB) yang telah dilaporkan meningkatkan akumulasi mineral yang dibutuh-kan untuk osteogenesis, seperti kalsium, magnesium, dan fosfor. Kami melaporkan kasus seorang anak perempuan berusia 14 tahun dengan gnatoschizis yang menjalani operasi cangkok tulang alveolar dan satu hari setelah operasi langsung dilanjutkan pemberian TOHB untuk meningkatkan proses penyembuhan tulang. Cangkok tulang iliaka autogenous digunakan untuk penutupan defek tulang di lokasi sumbing. Follow up pada hari ke 14 di poliklinik dengan pemeriksaan fisik pada defek lokasi sumbing mendapatkan hasil yang memuaskan. Simpulan laporan kasus ialah pada pasien ini diperoleh kontinuitas lengkung rahang atas, basis alar yang optimal, fistula dihilangkan, segmen rahang atas yang stabil untuk perawatan ortodontik, dan morfologi alveolar yang ideal yang menyokong tujuan akhir tatalaksana sumbing yaitu perbaikan kualitas hidup.Kata kunci: gnatoschizis; cangkok tulang alveolar; terapi oksigen hiperbarik

2016 ◽  
Vol 23 (10) ◽  
pp. 1252-1257
Author(s):  
Imran Sadiq ◽  
Muhammad Ramzan ◽  
Naseer Bashir Al Sharari ◽  
Yousaf al Oufi ◽  
Omar Khan

The role of steroids in the treatment of Bell’s palsy is well known provided patientspresent within 72hrs of symptoms onset. If patients present late or with severe Bell’s palsythe effect of steroids or other treatment modalities is not yet clear. Aim of this study was toevaluate the effect of HBOT along with oral steroids in treatment of such patients. Setting:Diving department at Armed Forces Hospital King Abdul Aziz Naval Base Jubail, Kingdom ofSaudi Arabia (KSA). Period: January 2010 to Dec. 2015. Methods: Bell’s palsy patients ofage 13 years and above were treated with steroids & HBOT. Prednisolone 60mg was givenorally for one week to all patients & those patients who could tolerate HBOT were selected fortreatment with Hyperbaric Oxygen in a closed chamber at 2.5 ATA, 90 minutes a day and fivedays a week. HBOT was continued till complete recovery or up to 20 sessions before declaringpartial recovery or failure. Assessment was done by physician using House-Brackmanngrading system for Facial nerve dysfunction. Patients were followed up to 3 months beforedeclaring partial recovery or treatment failure. Results: Treatment was started on 125 patientsbut 15 patients could not tolerate HBOT due to ear pain (10 patients) or high blood pressure(5 patients) in the HBOT chamber whereas 10 patients did not show up for follow up so only100 patients completed the treatment. Out of 100, 22(22%) patients had mild (grade I to II), 40patients (40%) had moderate (grade III to IV) and 38 patients (38%) had severe (grade V to VI)Bell’s palsy. Majority of patients (85%) presented after 72hrs of symptoms onset. At 3 monthsof follow up 90% (n=90) patients had full recovery whereas 10% (n=10) patients had partialrecovery. Severity of disease (OR 0.125, CI 0.025---0.6255, p =0.00595) and time between onsetof symptoms and start of treatment >2weeks (OR 0.0966 CI 0.0187---0.4987, p=0.00280) werestatistically significant. Conclusion: Combination of Hyperbaric Oxygen therapy and steroids is


2019 ◽  
Author(s):  
Jocefabia Reika Alves Lopes ◽  
Mariza D’Agostino Dias ◽  
João Antonio Correa ◽  
Maria Alice Bragagnolo Batalha ◽  
Luanda Karla Dantas Guerra

Abstract Background: Diabetic limb ulcers are highly prevalent and contribute to a significant increase in cost for the treatment of these patients in health services. However, healing of these wounds is a major health problem and may even lead to amputation. The aim of the current study is to evaluate the efficacy of hyperbaric oxygen therapy (HBOT) in facilitating the healing of diabetic foot ulcers and reducing the number of amputations in these patients.Methods : The study will be conducted in the city of Imperatriz, Maranhão from 2019 to 2020, in diabetic patients with chronic foot ulcers (classified as Wagner grade 2, 3, and 4, persisting for more than one month). The outpatient follow-up for diabetic foot patients will be done at the SUS (Unified Health System), with a sample size of 120 patients (60 patients for each arm). Half of the patients will receive standard treatment, i.e. dressings, debridement, antibiotics, and load relief, along with HBOT (HBOT group), and the other half will receive only standard treatment (control group). The patients of the HBOT group will be evaluated upon admission, after 10, 20, 30 and 35 HBOT sessions, and after six months. The patients of the control group will also be evaluated at equivalent periods. The progression of the wounds and specific treatment, such as appropriate bandage, antibiotic therapy, or need of some surgical intervention will be evaluated on a weekly basis. The SF-36 quality of life questionnaire will be filled upon admission and after three months of follow-up in both groups. Upon admission, the patients of both groups will undergo arterial Doppler ultrasound, and laboratory tests–complete blood count, erythrocyte sedimentation rate, C-reactive protein, creatinine, fasting blood glucose, and glycosylated haemoglobin.Discussion : Diabetic foot ulcers are a highly prevalent complication of diabetes with serious consequences. A study to assess the efficacy of HBOT in healing the ulcers and reducing the rate of amputations in diabetic patients is justified, which will eventually aid in the development of guidelines for treating these ulcers.


Oral Diseases ◽  
2019 ◽  
Vol 25 (3) ◽  
pp. 822-830 ◽  
Author(s):  
Kyeong‐Mee Park ◽  
Kyung‐Seok Hu ◽  
Hyunmin Choi ◽  
Seo‐Eun Oh ◽  
Hyeong‐Il Kim ◽  
...  

2012 ◽  
Vol 89 (2) ◽  
pp. 208-214 ◽  
Author(s):  
Teruhiro Nakada ◽  
Hiroko Nakada ◽  
Yasuyuki Yoshida ◽  
Yasuyo Nakashima ◽  
Yoshiaki Banya ◽  
...  

2009 ◽  
Vol 10 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Raheel Ahmed ◽  
Meryl A. Severson ◽  
Vincent C. Traynelis

Object Hyperbaric oxygen therapy (HBO) is used as primary and/or adjunctive therapy in the treatment of various clinical conditions complicated by local hypoxia. It may have therapeutic potential in the treatment of neurosurgical infections such as spinal osteomyelitis that are associated with significant morbidity rates. The purpose of this study was to evaluate the efficacy of HBO therapy in the treatment of spinal osteomyelitis. Methods The clinical records of patients diagnosed with spinal osteomyelitis who received HBO therapy during their treatment at the authors' institution over the past 10 years were retrospectively reviewed. Six adult patients were identified. Four patients had recently undergone spinal surgery and secondary spinal osteomyelitis had developed. These patients received adjunctive HBO therapy due to significant comorbidities and risk factors for poor healing. Results All patients remained symptom and infection free over the subsequent follow-up period. Two patients had primary spinal osteomyelitis that had recurred despite a full course of appropriate antimicrobial therapy. Infection control was achieved after HBO therapy in 1 patient. The mean follow-up period for the study group was 2.9 years (range 5 months to 5 years). Conclusions Hyperbaric oxygen therapy enabled infection cure in 5 of 6 patients with spinal osteomyelitis complicated by medical comorbidities or the failure of primary therapy. These results show that HBO may be a useful adjunctive therapeutic modality in the treatment of spinal osteomyelitis, particularly when there are medical comorbidities that increase the risk of poor healing. Hyperbaric oxygen therapy may also be beneficial in patients with relapsing primary spinal osteomyelitis after standard therapy has failed.


2016 ◽  
Vol 10 (3) ◽  
pp. 409-417
Author(s):  
Gabriel Pires Pastore ◽  
Ivan Solani Martins ◽  
Douglas Rangel Goulart ◽  
Alexandre Javaroni Prati ◽  
Márcio de Moraes ◽  
...  

2018 ◽  
Vol 98 (2) ◽  
pp. 481-489 ◽  
Author(s):  
Alain Mina ◽  
Leyla Shune ◽  
Haitham Abdelhakim ◽  
Tara L. Lin ◽  
Sid Ganguly ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Kyeong-Mee Park ◽  
Changdae Kim ◽  
Wonse Park ◽  
Young-Bum Park ◽  
Moon-Kyu Chung ◽  
...  

Objective. In this study, we evaluated changes in bone remodeling in an irradiated rat calvarial defect model according to duration of hyperbaric oxygen therapy. Materials and Methods. The 28 rats were divided into four groups. Radiation of 12 Gy was applied to the skull, and 5-mm critical size defects were formed on both sides of the skull. Bone grafts were applied to one side of formed defects. From the day after surgery, HBO was applied for 0, 1, and 3 weeks. At 6 weeks after bone graft, experimental sites were removed and analyzed for radiography, histology, and histomorphometry. Results. Micro-CT analysis showed a significant increase in new bone volume in the HBO-3 group, with or without bone graft. When bone grafting was performed, BV, BS, and BS/TV all significantly increased. Histomorphometric analysis showed significant increases in %NBA and %BVN in the HBO-1 and HBO-3 groups, regardless of bone graft. Conclusion. Hyperbaric oxygen therapy was effective for bone regeneration with only 1 week of treatment.


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