scholarly journals Discovering Rheumatoid Arthritis During Pregnancy

2021 ◽  
Vol 2 ◽  
pp. 18-19
Author(s):  
Fatoumata Diakité ◽  
Boureima Kodio ◽  
Seydou Diallo ◽  
Fanta Sangaré ◽  
MohomedineTouré Touré ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Visual Analogue Scale ◽  
Rheumatoid Factor ◽  
Analogue Scale ◽  
Morning Stiffness ◽  
Fetal Loss ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Inflammatory Syndrome ◽  
Peptide Antibodies

Rheumatoid arthritis is an autoimmune mechanism disease that preferentially affects women. Remission from rheumatoid arthritis has often been associated with pregnancy. A 29-year-old woman presented with symmetrical inflammatory polyarthralgias of the large and small joints with morning stiffness estimated at 5 hours, and the Visual Analogue Scale at 80/100 associated with the joint swelling onset 12th week of amenorrhea. She has no medical history, third pregnancy, and no fetal loss has been reported. The physical examination of the day objectified five painful joints and two swollen joints. Disease activity was moderate. There was a biological inflammatory syndrome with a C-Reactive Protein (CRP) at 37.9 mg. Rheumatoid factor was positive at 214 IU (Standard <14 IU), anti-citrullinated peptides antibodies at 99.6 IU (Standard <17 IU). The pregnancy revealed rheumatoid arthritis positive to rheumatoid factor and citrullinated cyclic anti-peptide antibodies.   

Multiple Intra-Articular Treatment of Rheumatoid Arthritis: A Randomized Prospective Study Comparing Rifamycin SV with Pefloxacin

1992 ◽  
Vol 20 (1) ◽  
pp. 27-39 ◽  
Author(s):  
J Caruso ◽  
L Boccassini ◽  
M Cazzola ◽  
S Santandrea ◽  
F Montrone ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Visual Analogue Scale ◽  
Prospective Study ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Analogue Scale ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Rifamycin Sv

In a randomized, prospective study the efficacy and tolerability of extensive multiple intra-articular administrations of two antibiotics, rifamycin SV and pefloxacin, were evaluated in 40 patients with classical or definite rheumatoid arthritis. Total weekly doses of 525 mg rifamycin or 560 mg pefloxacin were given for 10 weeks, and 12 months after treatment all clinical indices, erythrocyte sedimentation rate and C-reactive protein improved significantly in the rifamycin group. Some of the treatment indices (morning stiffness, severity of pain by visual analogue scale, grip strength and Ritchie's index) were already improved when the treatment ended, whereas others (erythrocyte sedimentation rate, C-reactive protein, number of painful and swollen joints) improved progressively during the follow-up. In the pefloxacin treatment group all indices except C-reactive protein and severity of pain determined using a visual analogue scale were significantly improved 12 months after treatment. Comparison of the two treatments showed a significant difference in erythrocyte sedimentation rate ( P < 0.047), Ritchie's index ( P < 0.036) and C-reactive protein ( P < 0.028) in favour of rifamycin.

scholarly journals The effect of limited versus no tourniquet use on rapid recovery in total knee replacement--a randomized controlled trial

2020 ◽  
Author(s):  
Jiandong Yin ◽  
XinLing Wang ◽  
Biao Zuo ◽  
Fei Chen ◽  
Yang Yu
Keyword(s):  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Enhanced Recovery ◽  
Controlled Trial ◽  
Venous Blood ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Hemoglobin C ◽  
Hss Score ◽  
No Tourniquet

Abstract Background: Tourniquets are widely used in TKA, but few articles state the difference in postoperative effects between restricting tourniquet use and not.Objective:We hoping that this experiment will look at the effect of limited tourniquet use on enhanced recovery in TKA. Methods: 150 patients who received TKA in the Affiliated Hospital of Chengdu University of TCM from June 2018 to December 2019 were randomly selected and randomly divided into 3 groups: ①limited use tourniquet group: after the completion of osteotomy, tourniquet was applied only when the prosthesis was installed, ②second half tourniquet group: Install prosthesis until suture is complete ③ no tourniquet group: no tourniquet was used throughout. The postoperative venous blood hemoglobin, C-reactive protein, visual analogue scale and HSS score were compared among the three groups. Results: Compared with the restricted use of tourniquet group, the visual analogue scale of knee joint pain and venous blood C-reactive protein level at 1 and 3 d after operation and hemoglobin level at 1 d after operation in the second half of tourniquet group increased and the HSS score at 3 and 7 d after operation decreased (P <0.05).No significant differences in visual analogue scale,HSS score,C-reactive,and hemoglobin between the restricted tourniquet and the no tourniquet. Conclusion: The results confirmed that the use of tourniquet in the second half of TKA would aggravate the early postoperative pain. In the effect of early rehabilitation, there is no significant between limited use of tourniquet or no use.

Evaluation of vascular endothelial growth factor levels in rheumatoid arthritis patients, with and without joint swelling; a comparison with erythrocyte sedimentation rate, C-reactive protein, rheumatoid factor and anti-cyclic citruillnated protein

2017 ◽  
Vol 43 (1) ◽  
pp. 76-82
Author(s):  
Alper Gümüş ◽  
Cihan Coşkun ◽  
Hümeyra Öztürk Emre ◽  
Musa Temel ◽  
Berrin Berçik İnal ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Rheumatoid Factor ◽  
Sedimentation Rate ◽  
Vascular Endothelial ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Endothelial Growth Factor

AbstractIntroduction:The aim of our study was to investigate the vascular endothelial growth factor levels in joint swelling-positive and joint swelling-negative rheumatoid arthritis patients and to then examine the relationship between conventional parameters such as the erythrocyte sedimentation rate and the levels of C-reactive protein, rheumatoid factor, and anti-cyclic citrullinated protein.Methods:Fifty-nine (52 women and seven men) rheumatoid arthritis patients and 25 (20 women and five men) healthy individuals volunteered for this study. The patient group was divided into two sub-groups based on whether or not they exhibited joint swelling.Results:The levels of vascular endothelial growth factor in the joint swelling-negative group were significantly different from those in the joint swelling-positive group, but they were not different from those in the control group (p=0.001 and p=0.72, respectively). We investigated the correlation between vascular endothelial growth factor and C-reactive protein levels (r=0.37, p=0.001). We also evaluated the diagnostic adequacy of vascular endothelial growth factor and created a ROC curve. The area under the curve was calculated to be 0.767.Conclusion:Vascular endothelial growth factor is an adequate diagnostic biomarker and can successfully be used to predict the occurrence of rheumatoid synovitis based on local inflammation.

scholarly journals The effectiveness of combined pulse therapy in patients with rheumatoid arthritis

2020 ◽  
pp. 83-84
Author(s):  
S.M. Shukurova
Keyword(s):  
Rheumatoid Arthritis ◽  
Analogue Scale ◽  
Average Duration ◽  
Pulse Therapy ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
American College Of Rheumatology ◽  
Estimated Parameters ◽  
Systemic Manifestations ◽  
High Doses

Objective. To study the efficacy of the tolerance of combined regimens of the therapy with high doses of methylprednisolone and methotrexate of the patients with rheumatoid arthritis (RA). Materials and methods. The study included 85 patients with RA who underwent inpatient treatment in the Rheumatologic Department of the Clinical Hospital of Dushanbe city for the period 2018-2019. From them, women – 83.2 %, men – 26.8 %; the average duration of the disease is 7.4 years. Extra-articular manifestations of RA were determined in 74.3 % of patients. Against the background of the standard therapy, a regimen of bolus pulse therapy (methylprednisolone 500-1000 mg and methotrexate) was taken for 3 days, which has been followed for observation for a year. The effectiveness of the treatment was assessed according to the American College of Rheumatology (ACR) 20/50/70 criteria. The number of the swollen joints and painful joints (NPV), ESR, C-reactive protein level, and the overall disease activity were determined. Results and discussion. After 1 month of therapy, significant positive dynamics were recorded in the all estimated parameters of the RA activity. There was a significant decrease in NPV, as well as the intensity of pain according to the visual analogue scale. During 3 months of observation, 78 % of the observed patients showed improvement and only 11 % of patients had side effects and have not been required of the discontinuation of the treatment. Conclusions. The combined pulse therapy of methylprednisolone and methotrexate was an effective and well-tolerated for systemic manifestations of RA and contributed to a significant decrease in RA activity in the shortest time.

scholarly journals A comparison of the vancomycin calcium sulfate implantation versus fenestration decompression for the treatment of sclerosing osteomyelitis

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Haotian Hua ◽  
Xinwei Wang ◽  
Jiangang Guo ◽  
Lei Zhang ◽  
Zairan Guo ◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Sedimentation Rate ◽  
Analogue Scale ◽  
Calcium Sulfate ◽  
Postoperative Hospital Stay ◽  
Tube Placement ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Scale Scores

Abstract Objective To compare the clinical efficacy of vancomycin calcium sulfate implantation and fenestration decompression in the treatment of sclerosing osteomyelitis. Method A retrospective analysis for 46 cases of sclerosing osteomyelitis were admitted to our department between June 2010 to June 2020. Twenty-one patients were treated with fenestration decompression, twenty-five patients were treated with vancomycin calcium sulfate implantation. The postoperative hospital stay, days of drainage tube placement, visual analogue scale scores, C-reactive protein and erythrocyte sedimentation rate were compared between the two groups. Results The visual analogue scale scores of both groups were significantly lower than before treatment (p < 0.05), but the difference between them was not statistically significant. Patients treated by vancomycin calcium sulfate implantation had shorter postoperative hospital stay and days of drainage tube placement compared to those treated by fenestration decompression (p < 0.05). C-reactive protein and erythrocyte sedimentation rate in both groups were significantly lower than before treatment, but the improvement effect of vancomycin calcium sulfate implantation was better (p < 0.05). Conclusion Both treatment methods can relieve pain effectively. Compared with fenestration decompression, vancomycin calcium sulfate implantation can shorten the treatment time effectively, control the infection better.

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