scholarly journals TO STUDY THE EFFICACY OF AUTOLOGOUS PLATELET RICH PLASMA OVER CONVENTIONAL MECHANICAL FIXATION METHODS IN SPLIT THICKNESS SKIN GRAFTING

2021 ◽  
pp. 1-4
Author(s):  
Ankur Deshwali ◽  
Peeyush Kesharwani ◽  
Rohan Gupta
Keyword(s):  
Skin Graft ◽  
Platelet Rich Plasma ◽  
Skin Grafting ◽  
Controlled Study ◽  
Study Group ◽  
Fixation Methods ◽  
Thickness Skin ◽  
Split Thickness Skin Grafting ◽  
Autologous Platelet Rich Plasma ◽  
Autologous Platelet

TITLE Efficacy of autologous platelet rich plasma over conventional mechanical fixation methods in split thickness skin grafting . AIMS AND OBJECTIVES to determine the efficacy of autologous platelet rich plasma over conventional mechanical fixation methods in split thickness skin grafting. METHODS  This a prospective randomized controlled study, conducted in the Department of surgery, SAIMS Medical College and P.G Institute, Indore for a period of two years from September 2016 to September 2018. A total of 20 patients were included in the study, and divided into two groups of 10 each randomly. The study was approved by the local ethical committee of our hospital. An informed written consent was obtained from all patients.  Total of 20 patients were studied; 10 cases were randomly chosen for study with autologous platelet rich plasma and 10 cases received conventional methods like staples/sutures used to anchor the skin grafts in a control group. RESULTS Autologous PRP showed faster and better healing rates. With PRP study group instant graft adherence was seen in all cases. Hematoma, graft edema, discharge from graft site, frequency of dressings and duration of stay in hospital were significantly less in the PRP. There were no adverse effects or reactions seen with the use of autologous PRP among the study group. CONCLUSION  The combination of PRP with Split Thickness Skin Graft (STSG) significantly improved clinical outcomes and shortened the wound healing time. Therefore, this treatment combination could provide a way to heal skin after skin graft reconstruction with minimal recovery time. It is found to be highly beneficial in many aspects both to the patient and surgeon based on our results.

scholarly journals Efficacy of autologous platelet rich plasma over conventional mechanical fixation methods in split thickness skin grafting

2018 ◽  
Vol 6 (1) ◽  
pp. 108 ◽  
Author(s):  
Girish Umashankar Thimmanahalli ◽  
Mahesh Kumar
Keyword(s):  
Skin Graft ◽  
Platelet Rich Plasma ◽  
Healing Process ◽  
Split Thickness Skin Graft ◽  
Skin Defect ◽  
Thickness Skin ◽  
Split Thickness Skin Grafting ◽  
Autologous Platelet Rich Plasma ◽  
Graft Reconstruction ◽  
Autologous Platelet

Background: Platelet-Rich Plasma (PRP) is an autologous product derived from whole blood through the process of gradient density centrifugation. After skin graft reconstruction, the healing process is longer and may be difficult, depending on the wound site, skin defect size, and patient comorbidities. The potential value of PRP lies in its ability to incorporate high concentrations of platelet-derived growth factors into the skin graft. Since not all patients afford commercially available recombinant platelet rich plasma for skin graft, platelet extract from patient’s own blood is being used in this study to test and demonstrate the therapeutic role of PRP in skin graft. The aim of this randomized, prospective study is to compare the effectiveness of PRP in skin graft with conventional method like sutures, staplers or glue.Methods: The source of data were the patients admitted as inpatients for the management of wounds to the department of general surgery, JSS Hospital, Mysore from September 2016 to September 2018. Total of 60 patients were studied; 30 cases were randomly chosen for study with autologous platelet rich plasma and 30 cases received conventional methods like staples/sutures used to anchor the skin grafts in a control group.Results: Autologous PRP showed faster and better healing rates. With PRP study group instant graft adherence was seen in all cases. Hematoma, graft edema, discharge from graft site, frequency of dressings and duration of stay in hospital were significantly less in the PRP. There were no adverse effects or reactions seen with the use of autologous PRP among the study group.Conclusions: The combination of PRP with Split Thickness Skin Graft (STSG) significantly improved clinical outcomes and shortened the wound healing time. Therefore, this treatment combination could provide a way to heal skin after skin graft reconstruction with minimal recovery time. It is found to be highly beneficial in many aspects both to the patient and surgeon based on our results.

Comparative analysis of the effectiveness of surgical techniques for the treatment of Miller Class I gingival recessions

2021 ◽  
Vol 26 (2) ◽  
pp. 150-157
Author(s):  
R. R. Farkhshatova ◽  
L. P. Gerasimova ◽  
I. T. Yunusov
Keyword(s):  
Connective Tissue ◽  
Soft Tissues ◽  
Platelet Rich Plasma ◽  
Class I ◽  
Study Group ◽  
Connective Tissue Graft ◽  
Group I ◽  
Autologous Platelet Rich Plasma ◽  
Group Ii ◽  
Autologous Platelet

Relevance. It is currently relevant to study and compare the effectiveness of the autologous connective tissue grafts and the combination of collagen-based and autologous platelet-rich plasma in the surgical treatment of Miller Class I gingival recessions.Materials and methods. We examined and treated 48 (20 male (41.67%) and 28 female (58.33%)) patients aged from 25 to 40 years with Miller Class I gingival recessions. All gingival recessions were treated surgically using a modified twolayer tunnel technique. The patients were divided into two groups according to the graft type. Group I (24 patients (50%) had a connective tissue graft from the hard palate. Group II (24 patients (50%) used the combination of the autologous platelet-rich plasma and 3D collagen matrix Fibromatrix for the regeneration of oral soft tissues. We removed the sutures on the 14th day. The patients were followed up on the 7th and 14th days and in 1.3 months.Results. 48 Miller Class I gingival recessions were treated between 2018 and 2020. The depth of gingival recessions averaged 3.5 ± 1.13 mm before treatment. The level of the attached keratinized gingiva regarding the cementoenamel junction significantly (p < 0.001) improved in both groups after the surgery. The width and thickness of the keratinized gingiva best increased in group II. The mean effectiveness of gingival recession treatment was 84% in study group I and 96% – in study group II. Pain syndrome, fibrinous plaque and soft tissue edema were insignificant in group II.Conclusion. The combination of the autologous platelet-rich plasma and Fibromatrix, collagen 3D matrix, for the regeneration of the oral soft tissues is a more effective technique for the treatment of Miller Class I gingival recessions. This technique has several advantages. It is minimally invasive, less painful, soft tissue postoperative swelling is less and the received volume of the attached keratinized gums is larger than with a connective tissue graft. 

scholarly journals Hyperpigmentation after surgery for a deep dermal burn of the dorsum of the hand: partial-thickness debridement followed by medium split-thickness skin grafting vs full-thickness debridement followed by thick split-thickness skin grafting

2016 ◽  
Vol 4 ◽  
pp. 1-11 ◽  
Author(s):  
Yoshitaka Kubota ◽  
Nobuyuki Mitsukawa ◽  
Kumiko Chuma ◽  
Shinsuke Akita ◽  
Yoshitaro Sasahara ◽  
...  
Keyword(s):  
Skin Graft ◽  
Skin Grafting ◽  
Japanese Patients ◽  
Interquartile Range ◽  
Split Thickness Skin Graft ◽  
Full Thickness ◽  
Color Spaces ◽  
Partial Thickness ◽  
Thickness Skin ◽  
Split Thickness Skin Grafting

Abstract Background Early excision and skin grafting are commonly used to treat deep dermal burns (DDBs) of the dorsum of the hand. Partial-thickness debridement (PTD) is one of the most commonly used procedures for the excision of burned tissue of the dorsum of the hand. In contrast, full-thickness debridement (FTD) has also been reported. However, it is unclear whether PTD or FTD is better. Methods In this hospital-based retrospective study, we compared the outcomes of PTD followed by a medium split-thickness skin graft (STSG) with FTD followed by a thick STSG to treat a DDB of the dorsum of the hand in Japanese patients. To evaluate postoperative pigmentation of the skin graft, quantitative analyses were performed using the red, green, and blue (RGB) and the hue, saturation, and brightness (HSB) color spaces. We have organized the manuscript in a manner compliant with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement. Results Data from 11 patients were analyzed. Six hands (five patients) received grafts in the PTD group and eight hands (six patients) received grafts in the FTD group. Graft take was significantly better in the FTD group (median 98 %, interquartile range 95–99) than in the PTD group (median 90 %, interquartile range 85–90) (P &lt; 0.01). Quantitative skin color analyses in both the RGB and HSB color spaces showed that postoperative grafted skin was significantly darker than the adjacent control area in the PTD group, but not in the FTD group. Conclusions There is a possibility that FTD followed by a thick STSG is an option that can reduce the risk of hyperpigmentation after surgery for DDB of the dorsum of the hand in Japanese patients. Further investigation is needed to clarify whether the FTD or the thick STSG or both are the factor for the control of hyperpigmentation.

scholarly journals Treatment of a Refractory Skin Ulcer Using Punch Graft and Autologous Platelet-Rich Plasma

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Mauro Carducci ◽  
Marcella Bozzetti ◽  
Marco Spezia ◽  
Giorgio Ripamonti ◽  
Giuseppe Saglietti
Keyword(s):  
Platelet Rich Plasma ◽  
Skin Grafting ◽  
Lower Limbs ◽  
Alternative Approach ◽  
Speed Up ◽  
Autologous Platelet Rich Plasma ◽  
Dermal Regeneration ◽  
Diabetic Wounds ◽  
Autologous Platelet ◽  
Chronic Ulceration

Background. Chronic ulceration of the lower legs is a relatively common condition amongst adults: one that causes pain and social distress and results in considerable healthcare and personal costs. The technique of punch grafting offers an alternative approach to the treatment of ulcers of the lower limbs.Objective. Combining platelet-rich plasma and skin graft enhances the efficacy of treating chronic diabetic wounds by enhancing healing rate and decreasing recurrence rate. Platelet-rich plasma could, by stimulating dermal regeneration, increase the take rate after skin grafting or speed up reepithelialization.Methods and Materials. The ulcer was prepared by removing fibrin with a curette and the edges of the ulcer were freshened. The platelet-rich plasma has been infiltrated on the bottom and edges of the ulcer. The punch grafts were placed in 5 mm holes arranged. The ulcer was medicated with hydrogel and a pressure dressing was removed after 8 days.Results. After a few days the patient did not report more pain. Granulation tissue appeared quickly between implants. Most of the grafts were viable in 2-3 weeks. The grafts gradually came together to close the ulcer and were completed in four months.

Sign in / Sign up

Export Citation Format

Share Document