RENAL FUNCTION AND CLINICAL PROFILE IN CHILDREN WITH CONGENITAL HEART DISEASE – AN OBSERVATIONAL STUDY FROM TERTIARY CARE HOSPITAL IN CENTRAL INDIA.

Purpose: To evaluate the renal function and clinical prole in children with congenital heart disease. Method: After taking informed consent from the parents of 118 children aged 1 month to 14 years were recruited in study. Anthropometry and vitals were noted. Complete physical examination and USG abdomen done to identify any other associated congenital anomaly. Laboratory evaluation of serum creatinine was done on day 1 and day 5. 24 hours urine output was strictly measured till day 5 of admission. Result: The maximum number of cases belonged to age group 1-6 month. Male children were affected more than females (1.5:1) and majority of the children belong to family of lower middle and lower socioeconomic status. Most of the children belong to rural area. Among syndromic features, microcephaly and cleft lip and cleft palate were most frequently observed. Most of the cases had weight /height <-3SD. There was no major signicant difference in mean value of urine output and serum creatinine level in different age groups and in between cyanotic and acyanotic group. Conclusion: Congenital heart disease forms a significant diagnosis in hospitalized children. Larger studies are needed to evaluate newer associations (like male gender and low socioeconomic status). Microcephaly and cleft lip/palate were most observed associated syndromic features. No signicant effect was observed on the mean urine output and serum creatinine level in children with congenital heart disease.

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Acute Kidney Injury

Pediatric Care Online ◽

10.1542/aap.ppcqr.396265 ◽

2020 ◽

Keyword(s):

Acute Kidney Injury ◽

Congenital Heart Disease ◽

Heart Disease ◽

Serum Creatinine ◽

Early Identification ◽

Urine Output ◽

Congenital Heart ◽

Kidney Injury ◽

Key Points

Key Points Awareness and early identification are important. Serum creatinine and urine output are key to assessing acute kidney injury. Congenital heart disease, sepsis, and nephrotoxic medications are major causes.

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Neighbourhood maternal socioeconomic status indicators and risk of congenital heart disease

BMC Pregnancy and Childbirth ◽

10.1186/s12884-020-03512-8 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Qun Miao ◽

Sandra Dunn ◽

Shi Wu Wen ◽

Jane Lougheed ◽

Jessica Reszel ◽

...

Keyword(s):

Socioeconomic Status ◽

Congenital Heart Disease ◽

Heart Disease ◽

Household Income ◽

Congenital Heart ◽

Population Based ◽

Income Poverty ◽

Lower Odds ◽

Logistic Regression Models ◽

Chd Risk

Abstract Background This study aimed to examine the relationships between various maternal socioeconomic status (SES) indicators and the risk of congenital heart disease (CHD). Methods This was a population-based retrospective cohort study, including all singleton stillbirths and live births in Ontario hospitals from April 1, 2012 to March 31, 2018. Multivariable logistic regression models were performed to examine the relationships between maternal neighbourhood household income, poverty, education level, employment and unemployment status, immigration and minority status, and population density and the risk of CHD. All SES variables were estimated at a dissemination area level and categorized into quintiles. Adjustments were made for maternal age at birth, assisted reproductive technology, obesity, pre-existing maternal health conditions, substance use during pregnancy, rural or urban residence, and infant’s sex. Results Of 804,292 singletons, 9731 (1.21%) infants with CHD were identified. Compared to infants whose mothers lived in the highest income neighbourhoods, infants whose mothers lived in the lowest income neighbourhoods had higher likelihood of developing CHD (adjusted OR: 1.29, 95% CI: 1.20–1.38). Compared to infants whose mothers lived in the neighbourhoods with the highest percentage of people with a university or higher degree, infants whose mothers lived in the neighbourhoods with the lowest percentage of people with university or higher degree had higher chance of CHD (adjusted OR: 1.34, 95% CI: 1.24–1.44). Compared to infants whose mothers lived in the neighbourhoods with the highest employment rate, the odds of infants whose mothers resided in areas with the lowest employment having CHD was 18% higher (adjusted OR: 1.18, 95% CI: 1.10–1.26). Compared to infants whose mothers lived in the neighbourhoods with the lowest proportion of immigrants or minorities, infants whose mothers resided in areas with the highest proportions of immigrants or minorities had 18% lower odds (adjusted OR: 0.82, 95% CI: 0.77–0.88) and 16% lower odds (adjusted OR: 0.84, 95% CI: 0.78–0.91) of CHD, respectively. Conclusion Lower maternal neighbourhood household income, poverty, lower educational level and unemployment status had positive associations with CHD, highlighting a significant social inequity in Ontario. The findings of lower CHD risk in immigrant and minority neighbourhoods require further investigation.

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Serum Creatinine Level and Renal Function in Children

Archives of Pediatrics and Adolescent Medicine ◽

10.1001/archpedi.1992.02160220118036 ◽

1992 ◽

Vol 146 (10) ◽

pp. 1232 ◽

Cited By ~ 1

Author(s):

James E. Springate

Keyword(s):

Renal Function ◽

Serum Creatinine ◽

Serum Creatinine Level ◽

Creatinine Level

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Ethnicity and socioeconomic status: Impact on the diagnosis of congenital heart disease

Journal of the American College of Cardiology ◽

10.1016/0735-1097(93)90393-f ◽

1993 ◽

Vol 21 (7) ◽

pp. 1722-1726 ◽

Cited By ~ 51

Author(s):

David E. Fixler ◽

Patricia Pastor ◽

Ellen Sigman ◽

Clayton W. Eifler

Keyword(s):

Socioeconomic Status ◽

Congenital Heart Disease ◽

Heart Disease ◽

Congenital Heart

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Classifying AKI by Urine Output versus Serum Creatinine Level

Journal of the American Society of Nephrology ◽

10.1681/asn.2014070724 ◽

2015 ◽

Vol 26 (9) ◽

pp. 2231-2238 ◽

Cited By ~ 206

Author(s):

John A. Kellum ◽

Florentina E. Sileanu ◽

Raghavan Murugan ◽

Nicole Lucko ◽

Andrew D. Shaw ◽

...

Keyword(s):

Serum Creatinine ◽

Serum Creatinine Level ◽

Creatinine Level ◽

Urine Output

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Asymmetric Crying Facies: Which Is the `Right-Wrong' Side?

PEDIATRICS ◽

10.1542/peds.71.1.144a ◽

1983 ◽

Vol 71 (1) ◽

pp. 144-145

Author(s):

KARL-GEORG EVERS ◽

PETER GRONECK

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Soft Palate ◽

Congenital Heart ◽

Cleft Lip ◽

Congenital Defects ◽

Wrong Side ◽

Organ Systems ◽

Depressor Muscle ◽

The Right

To the Editor.— Congenital asymmetric crying facies is generally considered to be due to unilateral agenesis or hypoplasia of the anguli oris depressor muscle (HAODM). Electromyographic (EMG) examinations of the affected sides have revealed absent spontaneous activity or diminished motor unit activity.1-3 Association of HAODM syndrome with congenital heart disease, the "cardiofacial syndrome," has been described.4 Major defects of other organ systems and minor congenital defects may be associated with asymmetric crying facies as well.5 Monreal6 reported five patients with asymmetric congenital crying facies syndroms who besides this anomaly displayed juxtaoral defects, egm atresia of one side of the jaw and soft palate, cleft lip, hypoplasis of mandible and ear.

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