AUTOLOGOUS SUCTION BLISTER EPIDERMAL GRAFTING FOR CHRONIC LEG ULCERS

2021 ◽  
pp. 41-42
Author(s):  
Nishant Lal ◽  
Aiswarya R Pillai ◽  
Shafy Ali Khan
Keyword(s):  
Donor Site ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Venous Ulcer ◽  
Wound Area ◽  
Compression Bandaging ◽  
Suction Blister ◽  
Chronic Leg Ulcers

Non healing ulcers are a burden to the patient as they are difcult to treat. They also affect patient's quality of life. A series of 2 patients – one with chronic venous ulcer and other with diabetic foot ulcer were included. Epidermal grafts were harvested and applied using Cellutome epidermal harvesting system (KCI) with no anesthesia. After transferring the harvest of epidermal blisters, 4 layer compression bandaging was given. Both the patients tolerated the procedure with no complications involving donor as well as recipient sites. Photographs were taken during various phases of healing. 1 week follow up showed 63% reduction in wound area. Donor site was completely healed by this time. Reduction in ulcer size of upto 99% was seen in 8 weeks.

scholarly journals Characteristics Predicting the Outcome in Individuals with Diabetic Foot Ulcerations

2017 ◽  
Vol 107 (3) ◽  
pp. 180-191 ◽  
Author(s):  
Lourdes Vella ◽  
Cynthia Formosa
Keyword(s):  
Ulcer Healing ◽  
Diabetic Foot ◽  
Health Care Professionals ◽  
Hemoglobin A1c ◽  
Foot Ulcer ◽  
Patient Characteristics ◽  
Outpatient Setting ◽  
Foot Complications

Background: We sought to determine patient and ulcer characteristics that predict wound healing in patients living with diabetes. Methods: A prospective observational study was conducted on 99 patients presenting with diabetic foot ulceration. Patient and ulcer characteristics were recorded. Patients were followed up for a maximum of 1 year. Results: After 1 year of follow-up, ulcer characteristics were more predictive of ulcer healing than were patient characteristics. Seventy-seven percent of ulcers had healed and 23% had not healed. Independent predictors of nonhealing were ulcer stage (P = .003), presence of biofilm (P = .020), and ulcer depth (P = .028). Although this study demonstrated that the baseline hemoglobin A1c reading at the start of the study was not a significant predictor of foot ulcer outcome (P = .603, resolved versus amputated), on further statistical analyses, when hemoglobin A1c was compared with the time taken for complete ulcer healing (n = 77), it proved to be significant (P = .009). Conclusions: The factors influencing healing are ulcer stage, presence of biofilm, and ulcer depth. These findings have important implications for clinical practice, especially in an outpatient setting. Prediction of outcome may be helpful for health-care professionals in individualizing and optimizing clinical assessment and management of patients. Identification of determinants of outcome could result in improved health outcomes, improved quality of life, and fewer diabetes-related foot complications.

scholarly journals Five-year follow-up of a cohort of people with their first diabetic foot ulcer: the persistent effect of depression on mortality

Diabetologia ◽  
2011 ◽  
Vol 55 (2) ◽  
pp. 303-310 ◽  
Author(s):  
K. Winkley ◽  
H. Sallis ◽  
D. Kariyawasam ◽  
L. H. Leelarathna ◽  
T. Chalder ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Persistent Effect

scholarly journals Temporoparietal Fascia Free Flap for a Large Nasal Septal Perforation

2019 ◽  
Vol 04 (01) ◽  
pp. e42-e46
Author(s):  
Nicholas G. Cuccolo ◽  
Ryan P. Cauley ◽  
Brady A. Sieber ◽  
Syed M.D. Hussain ◽  
Laurel K. Chandler ◽  
...  
Keyword(s):  
Medical Condition ◽  
Donor Site ◽  
Free Tissue Transfer ◽  
Donor Site Morbidity ◽  
Nasal Septal Perforation ◽  
Temporoparietal Fascia ◽  
Versatile Tool ◽  
Underlying Medical Condition

AbstractReconstruction of large nasal septal perforations can be a considerable challenge for surgeons. Reconstructive modalities are often determined by the size of the defect and the quality of local tissue and vasculature. Local and regional flaps may not provide enough tissue to achieve successful closure in patients with large perforations and those with baseline compromise of the nasal mucosa and blood supply from prior intervention or underlying medical condition. Microvascular free tissue transfer is a possible approach to reconstruction in these patients. We report a case of a 30-year-old man who presented with a large, symptomatic, 4 × 3.5 cm perforation as a result of prior functional septoplasty at an outside hospital. Reconstruction of the defect was accomplished in this setting with a free temporoparietal fascia (TPF) flap anastomosed to the columellar branch of the labial artery and the angular vein. Postoperative follow-up visits showed successful closure of the perforation without complications. As illustrated by this case, TPF flap is a versatile tool for complex nasal reconstructions. With minimal donor-site morbidity and rich vascularity capable of promoting remucosalization without the need for prelamination, the TPF flap may be suited for the repair of large nasoseptal perforations.

Comparison of Collagen Granule Dressing Versus Conventional Dressing in Patients With Diabetic Foot Ulcer

2020 ◽  
pp. 153473462093898
Author(s):  
Bayram Colak ◽  
Serdar Yormaz ◽  
Ilhan Ece ◽  
Akin Çalişir ◽  
Kazım Körez ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Healing Process ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Duration Of Treatment ◽  
Collagen Group ◽  
Physiological Serum ◽  
Better Than

Background. Diabetic foot ulcer (DFU) is a difficult, chronic wound with a significant long-term influence on the morbidity, mortality, and quality of life of patients. There is much information about the biochemical features of collagen and its function in wound healing. The aim of this study was to compare the results of DFU patients treated with and without collagen. Methods. A retrospective evaluation was made of the data of patients with DFU who underwent collagen treatment and physiological serum (PS) treatment. The patients were followed-up for a minimum of 12 weeks, and all complications, healing process, and wound characteristics were recorded. Results. Of the total 64 DFU patients included in the study, 30 were treated with PS and 34 with collagen. Complete closure was achieved in 17 (56.6%) of the PS group patients after 12 weeks of treatment. The rate was 25 (73.5%) in the collagen group. The mean duration of treatment was 9.2 weeks (range = 6-12 weeks) in the PS group and 8.08 weeks (range = 5-12 weeks) in the collagen group. The recovery time and recovery rates were determined to be better in the collagen group than in the PS group. Conclusion. A significant reduction in wound size was seen in the collagen group compared with the PS group. The results of this study demonstrated that collagen dressings are better than conventional dressings with regard to early granulation tissue and shorter hospital stay.

scholarly journals The Diabetic Foot Ulcer Scale (DFS): a quality of life instrument for use in clinical trials

2002 ◽  
Vol 19 (6) ◽  
pp. 167-175 ◽  
Author(s):  
Linda Abetz ◽  
Monica Sutton ◽  
Lesley Brady ◽  
Pauline McNulty ◽  
Dennis D. Gagnon
Keyword(s):  
Quality Of Life ◽  
Clinical Trials ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Life Instrument

Failure of a trial evaluating the effect of venous surgery on healing and recurrence rates in venous ulcers? The USABLE trial: rationale, design and methodology, and reasons for failure

2004 ◽  
Vol 19 (3) ◽  
pp. 137-142 ◽  
Author(s):  
A H Davies ◽  
A J Hawdon ◽  
R M Greenhalgh ◽  
S Thompson
Keyword(s):  
Controlled Trial ◽  
Venous Ulcer ◽  
Recurrence Rates ◽  
Compression Bandaging ◽  
Venous Ulcers ◽  
Number Of Patients ◽  
Venous Surgery ◽  
Ulcer Surgery ◽  
Set Up

Objective: This Medical Research Council funded trial was set up to investigate whether venous surgery provided any additional benefit in the healing and recurrence rates of venous ulcers over compression bandaging alone. Methods: Ulcer surgery as adjuvant to compression bandaging for leg ulcers (USABLE) was a multicentre, randomized controlled trial, which planned to recruit 1000 venous ulcer patients to receive either compression bandaging alone or compression bandaging plus venous surgery. Follow up recorded ulcer healing, recurrence and patient quality of life. Results: Recruitment was slow, and involved screening a large number of patients (759) with only 75 randomized over an 18-month recruitment period. Conclusions: The results would infer that surgery is unlikely to be a management option for the majority of patients presenting to a hospital with a gaiter area leg ulcer.

Impact of diabetic foot ulcer on health-related quality of life: A cross-sectional study

2015 ◽  
Vol 28 (3-4) ◽  
pp. 165-171 ◽  
Author(s):  
M. Sonal Sekhar ◽  
Roy Raymol Thomas ◽  
M.K. Unnikrishnan ◽  
K. Vijayanarayana ◽  
Gabriel Sunil Rodrigues
Keyword(s):  
Quality Of Life ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Quality of life in patients with diabetic foot ulcer in Visegrad countries

2017 ◽  
Vol 26 (9-10) ◽  
pp. 1245-1256 ◽  
Author(s):  
Jana Nemcová ◽  
Edita Hlinková ◽  
Ivan Farský ◽  
Katarína Žiaková ◽  
Darja Jarošová ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Visegrád Countries
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