scholarly journals CHOLELITHIASIS IN PEOPLE WITH NORMAL SERUM CHOLESTEROL: ROLE OF SERUM IRON

2021 ◽  
pp. 1-4
Author(s):  
Janaki R P Kumar P ◽  
Sreenivasa Rao Ch ◽  
Lakshmana Kumar N ◽  
Usha Kiran P
Keyword(s):  
Iron Deficiency ◽  
Serum Cholesterol ◽  
Serum Iron ◽  
Normal Serum ◽  
Cholesterol Concentration ◽  
Cholesterol Gallstones ◽  
Cholesterol Levels ◽  
Bile Cholesterol ◽  
Low Serum

INTRODUCTION: The old axiom that a typical gallstone patient is a fat, fertile female of forty is only partially true, as the disease has been found in women soon after their first delivery and also in underweight and thin people. So while searching the literature for different factors, the Iron deficiency was found to be a new and interesting etiological factor in the formation of gall stones. Although the cause is still unclear, cholesterol Gallstones develop most commonly in multiparous women. This patient population is also prone to chronic iron deficiency anemia (IDA). Previous studies claimed a cause-effect relationship between iron deficiency and cholesterol gallstones. AIM - To assess the association between Serum Iron and Bile Cholesterol levels in people with normal serum cholesterol levels, which reflects the effect of Serum Iron levels in the formation of Gallstones. MATERIALS AND METHODS – The study was conducted in the Department of General Surgery, G.S.L Medical College, and General Hospital over 18 months. A total of 49 patients with cholelithiasis and normal Serum Cholesterol levels were included in the study. Serum iron and Bile cholesterol contents were analyzed. RESULTS – It is observed that there is a significant association between increased incidence of Cholelithiasis and Low Serum Iron levels among people with normal levels of serum cholesterol. CONCLUSION – Low Serum Iron was associated with increased Bile Cholesterol concentration, indicating a possible role of Serum iron in forming gallstones.

THE EFFECT OF DIET, AGE, AND SEX ON CHOLESTEROL METABOLISM IN WHITE LEGHORN CHICKENS

1961 ◽  
Vol 39 (11) ◽  
pp. 1705-1715 ◽  
Author(s):  
J. D. Wood ◽  
J. Biely ◽  
J. E. Topliff
Keyword(s):  
Serum Cholesterol ◽  
Corn Oil ◽  
Cholesterol Metabolism ◽  
Control Diet ◽  
Dietary Cholesterol ◽  
Normal Serum ◽  
Cholesterol Concentration ◽  
Cholesterol Levels ◽  
Yolk Cholesterol ◽  
Age And Sex

The cholesterol metabolism of chickens differed in birds of different age and sex. The normal serum cholesterol levels were higher in females than in males and higher in 1-week-old chicks than in mature birds of the same sex. Laying hens were less susceptible to hypercholesterolemia induced by dietary cholesterol than were mature cockerels or young chicks of either sex. Corn oil tended to increase the degree of hypercholesterolemia in all cholesterol-fed birds except young cockerels. A vitamin-A-rich oil, dogfish liver oil, decreased the rise in serum cholesterol level in cholesterol-fed chicks of both sexes, but in mature birds it produced the opposite effect. The addition of 1% cholesterol to the control diet of hens increased the yolk cholesterol concentration of eggs laid by the birds and this increase in concentration was greatly enhanced if 10% corn oil was also present in the diet.

scholarly journals Influence of serum iron test results on the diagnosis of iron deficiency in children: a retrospective observational study

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e046865
Author(s):  
Gorkem Sezgin ◽  
Ling Li ◽  
Johanna Westbrook ◽  
Elisabeth Wearne ◽  
Denise Azar ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Observational Study ◽  
General Practitioners ◽  
Serum Ferritin ◽  
Serum Iron ◽  
Estimating Equation ◽  
Normal Serum ◽  
Retrospective Observational Study ◽  
Test Results ◽  
General Practices

Background and objectiveSerum iron results are not indicative of iron deficiency yet may be incorrectly used to diagnose iron deficiency instead of serum ferritin results. Our objective was to determine the association between serum iron test results and iron-deficiency diagnosis in children by general practitioners.Design, setting, patients and main outcome measuresA retrospective observational study of 14 187 children aged 1–18 years with serum ferritin and serum iron test results from 137 general practices in Victoria, Australia, between 2008 and 2018. Generalised estimating equation models calculating ORs were used to determine the association between serum iron test results (main exposure measure) and iron-deficiency diagnosis (outcome measure) in the following two population groups: (1) iron-deplete population, defined as having a serum ferritin <12 µg/L if aged <5 years and <15 µg/L if aged ≥5 years and (2) iron-replete population, defined as having a serum ferritin >30 µg/L.Results3484 tests were iron deplete and 15 528 were iron replete. Iron-deplete children were less likely to be diagnosed with iron deficiency if they had normal serum iron levels (adjusted OR (AOR): 0.73; 95% CI 0.57 to 0.96). Iron-replete children had greater odds of an iron-deficiency diagnosis if they had low serum iron results (AOR: 2.59; 95% CI 1.72 to 3.89). Other contributors to an iron-deficiency diagnosis were female sex and having anaemia.ConclusionSerum ferritin alone remains the best means of diagnosing iron deficiency. Reliance on serum iron test results by general practitioners is leading to significant overdiagnosis and underdiagnosis of iron deficiency in children.

scholarly journals Low serum cholesterol concentration and serotonin metabolism in men

BMJ ◽  
1996 ◽  
Vol 312 (7025) ◽  
pp. 221-221 ◽  
Author(s):  
P. H A Steegmans ◽  
D. Fekkes ◽  
A. W Hoes ◽  
A. A A Bak ◽  
E. van der Does ◽  
...  
Keyword(s):  
Serum Cholesterol ◽  
Cholesterol Concentration ◽  
Serotonin Metabolism ◽  
Serum Cholesterol Concentration ◽  
Low Serum

Association of personal and familial suicide risk with low serum cholesterol concentration in male lithium patients

2001 ◽  
Vol 104 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Alberto Bocchetta ◽  
Caterina Chillotti ◽  
Gianfranco Carboni ◽  
Antonio Oi ◽  
Marco Ponti ◽  
...  
Keyword(s):  
Serum Cholesterol ◽  
Suicide Risk ◽  
Cholesterol Concentration ◽  
Serum Cholesterol Concentration ◽  
Low Serum

scholarly journals Serum Iron Level as a Potential Predictor of Coronavirus Disease 2019 Severity and Mortality: A Retrospective Study

2020 ◽  
Vol 7 (7) ◽  
Author(s):  
Kang Zhao ◽  
Jucun Huang ◽  
Dan Dai ◽  
Yuwei Feng ◽  
Liming Liu ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Iron ◽  
Iron Status ◽  
Iron Concentration ◽  
Iron Level ◽  
Serum Iron Level ◽  
Amyloid A ◽  
Significant Difference ◽  
Before And After ◽  
Low Serum

Abstract Background Various types of pulmonary diseases are associated with iron deficiency. However, information on iron status in coronavirus disease 2019 (COVID-19) is scarce. Methods This study included 50 hospitalized patients with confirmed COVID-19. The role of serum iron in predicting severity and mortality of COVID-19 was evaluated. Results The most common symptoms of COVID-19 patients in this study were cough (82%), fever (64%), and chest distress (42%). Of the 50 patients, 45 (90%) patients had abnormally low serum iron levels (&lt;7.8 μmol/L). The severity of COVID-19 was negatively correlated with serum iron levels before and after treatment and was positively correlated with C-reactive protein, serum amyloid A, D-dimer, lactate dehydrogenase, urea nitrogen, and myoglobin levels. Decreased serum iron level could predict the transition of COVID-19 from mild to severe and critical illness. Seven (53.8%) patients with a lower serum iron level after treatment in the critical group had died. There was a significant difference in posttreatment serum iron levels between COVID-19 survivors and nonsurvivors. Conclusions Serum iron deficiency was detected in the patients with COVID-19. The severity and mortality of the disease was closely correlated with serum iron levels. Low serum iron concentration was an independent risk factor for death in COVID-19 patients.

THE EFFECT OF DIETARY MARINE FISH OILS ON THE SERUM CHOLESTEROL LEVELS IN HYPERCHOLESTEROLEMIC CHICKENS

1960 ◽  
Vol 38 (1) ◽  
pp. 19-24 ◽  
Author(s):  
J. D. Wood ◽  
Jacob Biely
Keyword(s):  
Marine Fish ◽  
Serum Cholesterol ◽  
Corn Oil ◽  
Cholesterol Concentration ◽  
Fish Oils ◽  
Shark Liver Oil ◽  
Serum Cholesterol Concentration ◽  
Cholesterol Levels ◽  
Clear Explanation ◽  
Basking Shark

An investigation was carried out into the effect of marine fish oils on the serum cholesterol levels in hypercholesterolemic chickens. The oils were fed at the 10% level in the diet. Lingcod liver oil and halibut liver oil prevented the hypercholesterolemic effect of supplementary cholesterol, whereas crude herring oil increased the hypercholesterolemia to the same extent as did corn oil and tallow. Ratfish liver oil, dogfish liver oil, and basking shark liver oil had less noticeable effects on the cholesterol levels. No clear explanation could be given for the observed behavior but there seemed to be a difference in the effects on serum cholesterol of liver oils from teleostei fish and from selachii fish, the former class of liver oils being much more potent in preventing the increase in serum cholesterol concentration in chickens caused by the addition of cholesterol to the diet.

THE EFFECT OF DIETARY MARINE FISH OILS ON THE SERUM CHOLESTEROL LEVELS IN HYPERCHOLESTEROLEMIC CHICKENS

1960 ◽  
Vol 38 (1) ◽  
pp. 19-24 ◽  
Author(s):  
J. D. Wood ◽  
Jacob Biely
Keyword(s):  
Marine Fish ◽  
Serum Cholesterol ◽  
Corn Oil ◽  
Cholesterol Concentration ◽  
Fish Oils ◽  
Shark Liver Oil ◽  
Serum Cholesterol Concentration ◽  
Cholesterol Levels ◽  
Clear Explanation ◽  
Basking Shark

An investigation was carried out into the effect of marine fish oils on the serum cholesterol levels in hypercholesterolemic chickens. The oils were fed at the 10% level in the diet. Lingcod liver oil and halibut liver oil prevented the hypercholesterolemic effect of supplementary cholesterol, whereas crude herring oil increased the hypercholesterolemia to the same extent as did corn oil and tallow. Ratfish liver oil, dogfish liver oil, and basking shark liver oil had less noticeable effects on the cholesterol levels. No clear explanation could be given for the observed behavior but there seemed to be a difference in the effects on serum cholesterol of liver oils from teleostei fish and from selachii fish, the former class of liver oils being much more potent in preventing the increase in serum cholesterol concentration in chickens caused by the addition of cholesterol to the diet.

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