Case of BRAF mutant Erdheim-Chester disease presenting with multisystem involvement: A case report
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Objective: Erdheim-Chester disease is a rare form of non-Langerhans cell histiocytosis of unknown etiology. It is a multisystemic disease that can involve bones, skin, brain, retroperitoneum, cardiovascular system, endocrine system, and lungs. Diagnosis is made by clinical findings, imaging results, and histopathological examination. BRAFV600E (B-rapidly accelerated fibrosarcoma gene) mutation is found in more than half of the cases. When Erdheim-Chester disease is not considered the differential diagnosis, it is not possible to diagnose and treat. In this case report, an Erdheim-Chester case with symptomatic, multisystem involvement, BRAFV600E mutation, and initiated vemurafenib treatment is presented in the light of literature data.
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2018 ◽
Vol 58
(4)
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pp. 161-165
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1999 ◽
Vol 14
(3)
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pp. 323
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2020 ◽
Vol 83
(6)
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pp. AB30
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