scholarly journals In-vitro evaluation of the antifungal activities of eel skin mucus from Asian swamp eel (Monopterus albus)

2019 ◽  
Vol 2 (1) ◽  
pp. 1-2
Author(s):  
Ayah Rebhi Hilles ◽  
Syed Mahmood ◽  
Mohd Arifin Kaderi ◽  
Ridzwan Hashim ◽  
Tara Jalal ◽  
...  
Keyword(s):  
Aspergillus Niger ◽  
Methanol Extract ◽  
Inhibition Zone ◽  
Diffusion Method ◽  
Microsporum Gypseum ◽  
Skin Mucus ◽  
Monopterus Albus ◽  
Antifungal Activities ◽  
Asian Swamp Eel ◽  
Swamp Eel

Discovery and development of new drugs from marine and freshwater animal remain one of the most challenging areas in recent marine sciences field. Thus, the object of current study to examine the antifungal activity of Asian swamp eel (Monopterus albus) skin mucus. Eel skin mucus aqueous and methanol extracts were prepared with different extract concentrations from 0.49 to 1000 μg/mL against fungus pathogens i.e. Aspergillus niger and Microsporum gypseum. The antifungal assay conducted using well diffusion method. The results showed a dose dependent decrease the fungal growth, at 100µl/well, the inhibition zone of methanol extract against M. gypseum (25.7±0.75) mm, while the aqueous one was (23.3±0.16) mm Whereas eel skin mucus methanol and aqueous extracts showed lower inhibition zone against Aspergillus niger at the same concentration which was (11.1±0.59) mm and (9.0±0.15) mm respectively. The methanol extract showed the highest inhibitory activity against M. gypseum because M. gypseum infect the upper layers of the skin and eel skin mucus protect eels from infections. The results were statistically significant with p < 0.001. In conclusion, the present study carried out to reveal the antifungal activities of eel skin mucus which might be use as a source of antifungal agent.

scholarly journals Activation of apoptotic cell death by skin mucus from Asian swamp eel (Monopterus albus) against human lung cancer cell line

2020 ◽  
Vol 24 ◽  
pp. 39
Author(s):  
Ayah Rebhi Hilles ◽  
Syed Mahmood ◽  
Mohd Arifin Kaderi ◽  
Ridzwan Hashim
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Apoptotic Cell ◽  
Thick Layer ◽  
Human Lung Cancer ◽  
Skin Mucus ◽  
Cell Lung Carcinoma ◽  
Monopterus Albus ◽  
Asian Swamp Eel ◽  
Swamp Eel

Asian swamp eel (Monopterus albus) is a freshwater fish which distributed widely in the East of India mainly across Malay Peninsula and Indochinese Peninsula, it is also broadly distributed in the Southern areas of East Asia including, southeastern China, Western Japanese Archipelago, and Korean Peninsula. It lives in muddy places, rice paddies, and slow-flowing currents areas. It has a unique morphological elongated body which is similar to snake and covered with a thick layer of the mucus. The objective of this study is to screen the cytotoxic activity of eel skin mucus extracts and to evaluate the mechanism of cell death whether it is apoptosis or necrosis based on caspases activity assays. For this purpose; eel skin mucus was collected from healthy fresh eels to prepare aqueous and methanol extracts. Preliminary cytotoxicity study was demonstrated against Non-small-cell lung carcinoma cell line (A549) using cell viability assay which revealed that methanol extract is more potent than aqueous extract; the revealed data was based on the response of ESM methanol and aqueous extracts to the relevant IC50 concentrations as IC50 values were 621±0.09 µg/mL and 845 ± 0.25 µg/mL respectively. Subsequently, the mechanism of cell death induced cell death through triggering apoptosis by the activation of caspase-3/7, 8 and 9. In conclusion, the present study has revealed the cytotoxic potentials of eel skin mucus which may lead to the development of new anticancer agents. 

Cloning and expression of Asian swamp eel (Monopterus albus) cxcr4 paralogues, and their modulation by pathogen infection

Aquaculture ◽  
2016 ◽  
Vol 457 ◽  
pp. 50-60 ◽  
Author(s):  
Weihua Gao ◽  
Liu Fang ◽  
Daiqin Yang ◽  
Kete Ai ◽  
Kai Luo ◽  
...  
Keyword(s):  
Cloning And Expression ◽  
Pathogen Infection ◽  
Monopterus Albus ◽  
Asian Swamp Eel ◽  
Swamp Eel

An Assessment of the Asian Swamp Eel (Monopterus albus) in Florida

2009 ◽  
Vol 18 (1) ◽  
pp. 25-39 ◽  
Author(s):  
Paul L. Shafland ◽  
Kelly B. Gestring ◽  
Murray S. Stanford
Keyword(s):  
Monopterus Albus ◽  
Asian Swamp Eel ◽  
Swamp Eel

scholarly journals Uji Aktivitas Antibakteri Ekstrak Metanol dan Fraksi Daun Kenikir (Cosmos caudatus Kunth) terhadap Salmonella typhi

2020 ◽  
Vol 8 (3) ◽  
pp. 177
Author(s):  
Achmad Syarifudin Noor ◽  
Bawon Triatmoko ◽  
Nuri Nuri
Keyword(s):  
Antibacterial Activity ◽  
Typhoid Fever ◽  
Ethyl Acetate ◽  
Methanol Extract ◽  
Inhibition Zone ◽  
Salmonella Typhi ◽  
Diffusion Method ◽  
Disk Diffusion Method ◽  
Water Fraction ◽  
Zone Diameter

The leaves of kenikir are known to have many benefits, one of which can be used as medicine. Kenikir leaves are reported to have antibacterial activity against the bacteria Salmonella typhi (S.typhi). S. typhi is a bacterium that causes typhoid fever. Typhoid fever is still an endemic disease in Asian countries, especially Indonesia. Typhoid fever became the third largest disease in Indonesia in 2010. The study related to the antibacterial activity of kenikir leaf fraction to S. typhi has never been reported. Therefore, it is necessary to conduct research related to the antibacterial activity of extracts and leaf fractions of kenikir to compare their potential against S. typhi. The study was conducted using the disk diffusion method using 5 series of concentrations namely 5%, 10%, 15%, 20%, and 30%. Tests were carried out on methanol extract, hexane, ethyl acetate, and methanol-water fraction. The results showed that highest inhibition zone diameter is 7,75 mm which is reached by methanol extract. The order of the highest inhibiting zone diameter are extract, hexane, ethyl acetate, and methanol-water fraction.

Effects of salinity on osmoregulation, growth and survival in Asian swamp eel (Monopterus albus)(Zuiew 1793)

2012 ◽  
Vol 45 (3) ◽  
pp. 427-438 ◽  
Author(s):  
Pil Birkefeldt Møller Pedersen ◽  
Kasper Hansen ◽  
Do Thi Thanh Houng ◽  
Mark Bayley ◽  
Tobias Wang
Keyword(s):  
Monopterus Albus ◽  
Growth And Survival ◽  
Asian Swamp Eel ◽  
Swamp Eel
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