scholarly journals FAMCICLOVIR IN THERAPY OF ATOPIC DERMATITIS PATIENTS WITH HERPES SIMPLEX INFECTION

2013 ◽  
Vol 10 (5) ◽  
pp. 61-69
Author(s):  
I N Zuikova ◽  
A E Shulzhenko ◽  
E S Fedenko ◽  
O G Elisutina
Keyword(s):  
Atopic Dermatitis ◽  
Herpes Simplex ◽  
High Frequency ◽  
Age Groups ◽  
Antiviral Drug ◽  
Patterns Of Use ◽  
Simplex Infection ◽  
Acyclic Nucleoside ◽  
Simplex Virus ◽  
Selection Of

The prevalence of herpes simplex virus in different age groups, the high frequency of relapsing forms of infection, torpid course, postherpetic complications are relevant medical and social problems. Often, practitioners create significant difficulties in establishing the diagnosis, choice of strategy in patients with herpes simplex. The paper presents the methods of diagnosis of herpes simplex and their application in atopic dermatitis patients, issues of acyclic nucleoside therapy (acyclovir, famciclovir) in different clinical forms of herpes simplex with individual approach to the selection of an antiviral drug and patterns of use.

scholarly journals Herpes simplex virus: selection of origins of DNA replication

1997 ◽  
Vol 25 (9) ◽  
pp. 1753-1760 ◽  
Author(s):  
O. Hammarsten ◽  
P. Elias
Keyword(s):  
Herpes Simplex Virus ◽  
Dna Replication ◽  
Herpes Simplex ◽  
Simplex Virus ◽  
Selection Of

Herpes simplex virus 1 proteins can induce skin inflammation in an atopic dermatitis‐like mouse model

2021 ◽  
Author(s):  
Natalija Novak ◽  
Heike Weighardt ◽  
Rafael Valdelvira ◽  
Elena Izquierdo ◽  
Irmgard Förster ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Mouse Model ◽  
Skin Inflammation ◽  
Herpes Simplex Virus 1 ◽  
Simplex Virus

Langerhans Cell—and T-Lymphocyte Functions in Patients With Atopic Dermatitis With Disseminated Cutaneous Herpes Simplex Virus Infection

1987 ◽  
Vol 89 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Liisa Räsänen ◽  
Maili Lehto ◽  
Timo Reunala ◽  
Christer Jansén ◽  
Matti Lehtinen ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Infection ◽  
T Lymphocyte ◽  
Herpes Simplex Virus Infection ◽  
Langerhans Cell ◽  
Simplex Virus

scholarly journals Diagnosis of Neonatal Herpes Simplex Infection from the Placenta

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Amanda E. Smith ◽  
Amy McKenney ◽  
Laura Rabinowitz ◽  
Anirudha Das
Keyword(s):  
Herpes Simplex ◽  
Intrauterine Infection ◽  
High Rate ◽  
Pathological Examination ◽  
Neonatal Herpes ◽  
Fetal Demise ◽  
First Case ◽  
Simplex Infection ◽  
Neonatal Herpes Simplex ◽  
Simplex Virus

Due to a high rate of fetal demise and premature birth in intrauterine HSV infection, the outcome in neonates is usually adverse. A female preterm infant with a gestational age of 25 1/7 weeks with expected early clinical course tested positive for neonatal herpes simplex virus (HSV) 2 after the neonatologist was informed of positive immunohistochemistry for the virus on the fifth day of life by the pathologist. Pathological examination of the placenta had revealed subacute necrotizing inflammation with stromal cell necrosis suggestive of intrauterine infection, possibly ascending due to prolonged rupture of membranes. To the best of our knowledge, this is the first case wherein placental pathology indicated exposure to HSV in utero before the infant presented with signs or symptoms of neonatal HSV resulting in a favorable outcome for the infant. Due to the variability of presentation of intrauterine HSV infection, pathological examination of the placenta in the first 2–5 days of life in premature infants can provide clues to the diagnosis of neonatal HSV which may significantly impact the outcome.

Herpes Simplex: A Possible Cause of Brain-Stem Encephalitis

PEDIATRICS ◽  
1977 ◽  
Vol 59 (2) ◽  
pp. 240-243
Author(s):  
Patricia H. Ellison ◽  
Peggy A. Hanson
Keyword(s):  
Herpes Simplex ◽  
Brain Stem ◽  
Central Nervous System Infection ◽  
Tracheal Aspirate ◽  
Acute Onset ◽  
Simplex Infection ◽  
Cranial Nerve Palsies ◽  
Criteria For Diagnosis ◽  
Simplex Virus ◽  
Brain Stem Encephalitis

Herpes simplex virus was isolated from the tracheal aspirate of a 10-year-old boy presenting with acute onset of multiple cranial nerve palsies and a mild right hemiparesis. There was also an elevated herpes complement-fixation titer with decrease in the following weeks. Although the criteria for diagnosis of central nervous system infection by herpes virus have been debated, we propose that this represents a case of brain-stem encephalitis due to herpes simplex infection. The importance of early diagnosis and evaluation of therapy are emphasized by this case in which the patient recovered completely.

High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion

1981 ◽  
Vol 1 (8) ◽  
pp. 743-752
Author(s):  
R M Sandri-Goldin ◽  
A L Goldin ◽  
M Levine ◽  
J C Glorioso
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Protoplast Fusion ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
High Frequency ◽  
Mammalian Cells ◽  
Frequency Transfer ◽  
Simplex Virus

The protoplast fusion technique of Schaffner (W. Schaffner, Proc. Natl. Acad. Sci. U.S.A. 77:2163-2167, 1980) has been adapted to introduce cloned herpes simplex virus genes into cultured mammalian cells. The technique involves digesting bacterial cell walls with lysozyme to produce protoplasts and then fusing the protoplasts to mammalian cells by treatment with polyethylene glycol. For monitoring transfer, protoplasts were labeled with the fluorescent dye fluorescein isothiocyanate before fusion. After fusion, greater than 50% of the mammalian cells were fluorescent, demonstrating that bacterial material was transferred with high frequency. Transfer of plasmid pBR325 occurred at frequencies of 1 to 2%, as measured by in situ hybridization. Fusion transfer of a chimeric plasmid consisting of the herpes simplex virus type 1 (strain KOS) EcoRI fragment F in pBR325 resulted in expression of some viral genomic sequences in about 5% of the mammalian cells, as detected by indirect immunofluorescence. One Ltk- cell in 300 to 500 was transformed to the TK+ phenotype after fusion with protoplasts carrying the chimeric plasmid pX1, which consists of pBR322 and the BamHI fragment coding for the herpes simplex virus type 1 thymidine kinase gene.

Sign in / Sign up

Export Citation Format

Share Document