scholarly journals Epidermal barrier disfunction correction in atopic dermatitis patients

2013 ◽  
Vol 10 (3) ◽  
pp. 57-60
Author(s):  
S M Shvets ◽  
O G Elisyutina

In the article data about epidermal barrier disfunction in atopic dermatitis patients and modern approaches to their correction with use of modern skin-care products are submitted.

2017 ◽  
Vol 14 (2) ◽  
pp. 76-81
Author(s):  
O G Elisyutina ◽  
A O Litovkina ◽  
E S Fedenko

Atopic dermatitis - chronic allergic skin inflammatory disease with genetic predisposition, dysbalance of immune response, dysfunction of an epidermal barrier and influence of various exogenous and endogenous factors. Epidermal barrier dysfunction leads to rising of permeability of a skin for allergens, microbs and nonspecific stimuli, as well as to sensitivity to various external influences. Clinically these implications are shown by skin xerosis symptoms therefore. According to modern clinical guidelines, the moisturizing agents, so called emollients, have to be used at all disease stages. Own data on use of modern skin care series Atopic® in complex therapy of atopic dermatitis patients are presented in the article.


2021 ◽  
pp. 40-42
Author(s):  
Jayakar Thomas

Atopic dermatitis is a chronic relapsing inammatory skin disorder with a complex pathogenesis involving genetic susceptibility, immunologic and epidermal barrier dysfunction, and environmental factors. Pruritus is a primary symptom; skin lesions range from mild erythema to severe lichenication to erythroderma. Diagnosis is by history and examination. Treatments include counseling on appropriate skin care, avoidance of triggers, and topical corticosteroids and immunosuppressants. Control of pruritus and superinfections is also important. Severe cases may require systemic immunosuppressive treatment. Childhood atopic dermatitis frequently resolves or lessens signicantly by adulthood.


2007 ◽  
Vol 82 (1) ◽  
pp. 79-85
Author(s):  
Jon M. Hanifin

This review summarizes the general approach and philosophy of managing difficult atopic dermatitis. There are as many regimens as there are physicians, but too many fail to provide patients with adequate relief. This leads to the wasteful alternative - an allergy-seeking behavior that makes caring for these patients even more complicated. If we, as dermatologists, provide rational counseling on prevention and skin care along with effective, stable, anti-inflammatory therapy, our patients may stop seeking irrational approaches. The new flood of information relating to epidermal barrier provides a basis for seeking and treating xerotic conditions earlier during infancy with the hope that the increasing problems with atopic dermatitis and asthma may be lessened with simple and safe measures.


2013 ◽  
Vol 75 (1) ◽  
pp. 65-71
Author(s):  
Katsuko KIKUCHI ◽  
Maki OZAWA ◽  
Setsuya AIBA ◽  
Eishin MORITA

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