scholarly journals Influence of complex physical rehabilitation on the dynamics of recovery of cognitive functions in patients who have been cerebral ischemic stroke

Author(s):  
Valeriia Mishchenko

The article presents the results of a study of the effect of a complex physical rehabilitation on the dynamics of restoration of cognitive impairments in patients in the early recovery period of the cerebral ischemic stroke. The study included 83 patients. All patients under study were distributed to the main group and the comparison group. The average age of the patients was 66,0 ± 2,3 years. Patients of two groups received standard drug therapy aimed at secondary prophylaxis. The patients under study from the main group additionally undertook a course of physical rehabilitation treatment within 21 days. Assessment of the condition of cognitive functions was carried out with the help of psychodiagnostic scales before the onset and after completion of treatment. The study showed that the use of a complex rehabilitation treatment, which includes drug therapy within the framework of secondary prophylaxis and course of physical rehabilitation can significantly affect the improvement of the state of moderately impaired cognitive functions in patients with a hemispheric ischemic stroke.

The article consideres the issue of restoring lost motor function through comprehensive physical rehabilitation. The results of a study of 84 patients with cerebral ischemic stroke (CIS) are presented. The study of patients was conducted in the recovery period (from 3 to 6 months after the vascular accident). The average age of patients was 64.2±1.7 years. During the study all patients were divided into two groups depending on the type of rehabilitation treatment. The main group consisted of 43 patients who received standard medicines therapy aimed at secondary prevention (antihypertensive, hypocholesterolemic, hypoglycemic and other medicines), as well as therapy aimed at the correction and prevention of neurocognitive and dyscirculatory disorders (medicines with metabolic and vasoactive action) during the entire period of supervision. All patients of the main group underwent a course of comprehensive physical rehabilitation treatment. The latter included classes in kinesiotherapy, occupational therapy, speech therapy classes and, if necessary, patients received psycho-correctional and psychotherapeutic methods of treatment. The second (comparison) group consisted of 41 patients who received only drug treatment: standard basic therapy in the framework of secondary prevention of CIS and therapy aimed at the correction and prevention of neurocognitive, dyscirculatory disorders. The results of our study showed that the use of a comprehensive rehabilitation treatment program consisting of physical and medical methods are signifi cantly more eff ective for patients with motor disorders who have suff ered an ischemic stroke compared with the use of only drug therapy in these patients.


Pathologia ◽  
2019 ◽  
Vol 0 (2) ◽  
Author(s):  
O. A. Koziolkin ◽  
S. O. Miedviedkova ◽  
L. O. Shevchenko ◽  
І. М. Liakhova ◽  
S. M. Malakhovа ◽  
...  

Author(s):  
Anna A. Mikhailova ◽  
Natalya B. Korchazhkina ◽  
Elizaveta S. Koneva ◽  
Konstantin V. Kotenko

BACKGROUND: Currently, the development and implementation of new effective comprehensive programs for medical rehabilitation of patients who have undergone acute cerebrovascular accident is an important and urgent medical problem. AIMS: To study the effect of combined methods of medical rehabilitation in patients with post-stroke spasticity on cognitive functions and psychoemotional status. MATERIAL AND METHODS: The study involved 60 patients who underwent ischemic stroke with movement disorders in the form of hemiparesis with increased muscle tone in the form of spasticity in the long-term period. Patients of the control group (30 people) underwent standard drug therapy and medical rehabilitation, patients of the main group (30 people), against the background of standard drug therapy and medical rehabilitation, used combined physiotherapy methods from the Alpha LED Oxy Light Spa apparatus. Subjective indicators of cognitive impairment (Montreal Cognitive Assessment Scale) and psychoemotional defects (Hospital Anxiety and Depression Scale) were assessed. RESULTS: Immediately after treatment on day 14, cognitive functions significantly improved and the degree of psychoemotional defect decreased, which was confirmed by the MOCA and HADS scales. CONCLUSION: The inclusion of combined physiotherapy methods in the standard complex of medical rehabilitation and treatment of patients after ischemic stroke with movement disorders in the form of hemiparesis contributes to a significant improvement in cognitive functions and a decrease in the degree of psychoemotional impairment.


Author(s):  
Yu. O. Novikov ◽  
I. E. Salakhov

Introduction. According to the defi nition of the World Health Organization (WHO), tension-type headache (TTH) is the most common type of primary headache. Rehabilitation of patients with chronic tension-type headache continues to be an important socio-medical problem. Its main goal is the most complete restoration of the functions of the musculoskeletal system of the neck, the correction of vascular and psychoemotional problems, and the patient′s return to his everyday life and work. As a rule, the main emphasis in the treatment of such patients is placed primarily on drug therapy. At the same time, practitioners are faced with a number of problems — the low effectiveness of the treatment, the nonpersistency of the results, allergic reactions, polypharmacy and others. All this suggests that there is a need for differentiated rehabilitation treatment of patients with tension-type headache with the use of various non-pharaceutical methods. The goal of research — to evaluate the clinical effi cacy of complex non-drug therapy in patients with tension-type headache.Materials and methods. The prospective controlled randomized study, which was conducted from October 2017 to March 2019 at the Department of Medical Rehabilitation of the Bashkir State Medical University, included 110 patients with TTH from the age of 20 to 45 years. All patients, depending on the treatment methodology used, were randomly divided into two groups of 55 people. Patients of the main group received complex rehabilitation treatment with the use of non-drug methods: osteopathic correction, acupuncture and exercise therapy. Patients in the control group received treatment in accordance with the standard of medical care for TTH (analgesics, non-steroidal antiinfl ammatory drugs, antidepressants, vasoactive and nootropic drugs). The study of the clinical effectiveness of the therapy included: an assessment of the severity of pain with the use of a visual analogue scale and a tensoalgimeter, a goniometric study with an assessment of the volume of active movements in the cervical spine, transcranial ultrasound dopplerography with an assessment of quantitative indicators in the system of the middle cerebral artery.Results. The use of complex non-drug therapy in patients with TTH compared with standard drug therapy leads to a signifi cantly more important decrease in the severity of pain, an increase in pain threshold, an increase in the volume of active movements in the cervical spine. The effect of non-drug treatment methods on blood fl ow in the system of the middle cerebral artery is comparable in its effectiveness with the use of pharmaceutical drugs.Conclusion. The proposed complex rehabilitation treatment of patients with TTH with the use of non-drug methods has shown clinical effi cacy which is comparable, and in a number of indicators, superior to the effectiveness of conventional medical treatment. All this determines the necessity of wider implementation of multidisciplinary non-drug treatment of patients with this pathology.


2019 ◽  
Vol 17 (3) ◽  
pp. 329-336
Author(s):  
Wang Jinli ◽  
Xu Fenfen ◽  
Zheng Yuan ◽  
Cheng Xu ◽  
Zhang Piaopiao ◽  
...  

Cardiovascular disease including cerebral ischemic stroke is the major complication that increases the morbidity and mortality in patients with diabetes mellitus as much as four times. It has been well established that irisin, with its ability to regulate glucose and lipid homeostasis as well as anti-inflammatory and anti-apoptotic properties, has been widely examined for its therapeutic potentials in managing metabolic disorders. However, the mechanism of irisin in the regulation of cerebral ischemic stroke remains unclear. Using PC12 cells as a model, we have shown that hypoxia/reoxygenation inhibits cell viability and increases lactic dehydrogenase. Irisin, in a dose-dependent manner, reversed these changes. The increase in inflammatory mediators (IL-1β, IL-6, and TNF-α) by hypoxia/reoxygenation was reversed by irisin. Furthermore, the cell apoptosis promoted by hypoxia/reoxygenation was also inhibited by irisin. Irisin suppressed TLR4/MyD88 signaling pathway leading to amelioration of inflammation and apoptosis in PC12 cells. Thus, inhibition of TLR4/MyD88 signaling pathway via irisin could be an important mechanism in the regulation of hypoxia/reoxygenation-induced inflammation and apoptosis in PC12 cells.


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