scholarly journals Generation of Hematopoietic-Like Stem Cells from Adult Human Peripheral Blood Following the Treatment with Platelet-Derived Mitochondria

2020 ◽  
Author(s):  
Haibo Yu ◽  
Wei Hu ◽  
Xiang Song ◽  
Dante Descalzi-Montoya ◽  
Zheng Yang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Adult Human

scholarly journals Primitive Stem Cells in Adult Human Peripheral Blood

2017 ◽  
Vol 1 (1) ◽  
pp. 1-8
Author(s):  
Henry E. Young ◽  
Frank Lochner ◽  
Deborah Lochner ◽  
Douglas Lochner ◽  
Gypsy F. Black ◽  
...  
Keyword(s):  
Stem Cells ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Adult Human

scholarly journals Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Angela Duong ◽  
Alesya Evstratova ◽  
Adam Sivitilli ◽  
J. Javier Hernandez ◽  
Jessica Gosio ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Peripheral Blood Mononuclear Cells ◽  
Pluripotent Stem Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Human Peripheral Blood ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells ◽  
Induced Pluripotent

AbstractMitochondrial health plays a crucial role in human brain development and diseases. However, the evaluation of mitochondrial health in the brain is not incorporated into clinical practice due to ethical and logistical concerns. As a result, the development of targeted mitochondrial therapeutics remains a significant challenge due to the lack of appropriate patient-derived brain tissues. To address these unmet needs, we developed cerebral organoids (COs) from induced pluripotent stem cells (iPSCs) derived from human peripheral blood mononuclear cells (PBMCs) and monitored mitochondrial health from the primary, reprogrammed and differentiated stages. Our results show preserved mitochondrial genetics, function and treatment responses across PBMCs to iPSCs to COs, and measurable neuronal activity in the COs. We expect our approach will serve as a model for more widespread evaluation of mitochondrial health relevant to a wide range of human diseases using readily accessible patient peripheral (PBMCs) and stem-cell derived brain tissue samples.

Effects of glucocorticoids and mineralocorticoids on proliferation and maturation of human peripheral blood stem cells

1999 ◽  
Vol 62 (2) ◽  
pp. 65-73 ◽  
Author(s):  
St�phanie Grafte-Faure ◽  
Catherine Leveque ◽  
Marc Vasse ◽  
Claudine Soria ◽  
Vic Norris ◽  
...  
Keyword(s):  
Stem Cells ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Peripheral Blood Stem Cells ◽  
Blood Stem Cells

scholarly journals Derivation of Induced Pluripotent Stem Cells from Human Peripheral Blood T Lymphocytes

PLoS ONE ◽  
2010 ◽  
Vol 5 (6) ◽  
pp. e11373 ◽  
Author(s):  
Matthew E. Brown ◽  
Elizabeth Rondon ◽  
Deepika Rajesh ◽  
Amanda Mack ◽  
Rachel Lewis ◽  
...  
Keyword(s):  
Stem Cells ◽  
T Lymphocytes ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Induced Pluripotent

Optimal cooling and warming conditions for preservation of human peripheral blood stem cells

Cryobiology ◽  
1980 ◽  
Vol 17 (6) ◽  
pp. 594-595
Author(s):  
L.E. Mcgann ◽  
A.R. Turner ◽  
M.J. Allalunis ◽  
J.M. Turc
Keyword(s):  
Stem Cells ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Peripheral Blood Stem Cells ◽  
Blood Stem Cells

scholarly journals Isolation of mesenchymal stem cells from G-CSF-mobilized human peripheral blood using fibrin microbeads

2006 ◽  
Vol 37 (10) ◽  
pp. 967-976 ◽  
Author(s):  
I Kassis ◽  
L Zangi ◽  
R Rivkin ◽  
L Levdansky ◽  
S Samuel ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Peripheral Blood ◽  
Human Peripheral Blood
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