scholarly journals The Efficacy and Safety of Uractiv Control in Overactive Bladder Treatment

2020 ◽  
Vol 71 (1) ◽  
pp. 390-394
Author(s):  
Calin Bogdan Chibelean ◽  
Veronica Ghirca ◽  
Razvan-Cosmin Petca ◽  
Daniel Porav-Hodade ◽  
Ioan Alin Nechifor-Boila ◽  
...  
Keyword(s):  
Placebo Group ◽  
Side Effects ◽  
Overactive Bladder ◽  
Prospective Study ◽  
Treatment Option ◽  
Alternative Treatment ◽  
Control Group ◽  
Efficacy And Safety ◽  
A Prospective Study ◽  
Safe Treatment Option

The aim of this study is to evaluate the efficacy and safety of Uractiv Control as an alternative treatment with no side effects in Overactive Bladder (OAB). We performed a prospective study over a period of 15 months (May 2018- September 2019) in Department of Urology from Targu-Mureș. We included 165 patients diagnosed with OAB wet (129 patients) and dry form (36 patients) which were fully evaluated over a 3-month period of treatment. 48 patients were treated with placebo 1 month and were evaluated by the same parameters like Uractiv Control group. The frequency of micturition during the day and night after the treatment with Uractiv Control was improved compared to placebo group (p=0.0001) and also the loss of urine episodes (p=0.03). Patients did not report any significant side effects of the treatment. Uractiv Control represents a safe treatment option with no side effects and improvement of the storage in OAB.

scholarly journals Solifenacin in Multiple Sclerosis Patients with Overactive Bladder: A Prospective Study

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Farida van Rey ◽  
John Heesakkers
Keyword(s):  
Multiple Sclerosis ◽  
Side Effects ◽  
Overactive Bladder ◽  
Prospective Study ◽  
Outcome Measure ◽  
Dose Increase ◽  
Neurogenic Disease ◽  
Multiple Sclerosis Patients ◽  
A Prospective Study ◽  
Disease Specific

Objective. To assess the efficacy and the effect on Qol of solifenacin for the treatment of OAB in MS patients.Patients and Methods. Thirty MS patients suffering from OAB were treated with solifenacin 5/10 mg for 8 weeks. The first 4 weeks patients received solifenacin 5 mg. At week 4 patients could request a dose increase to 10 mg. The efficacy was evaluated at 8 weeks.Results. After 4 weeks of treatment, 28 patients reported acceptable or no side effects. 17 continued the study with the 10 mg dosage, and 11 stayed on 5 mg solifenacin. Two patients withdrew from the study due to side effects. Solifenacin 5/10 mg for 8 weeks resulted in a significant decrease in number of micturitions and number of pads used per day compared to baseline. Also the severity of urgency prior to voiding decreased significantly, and an increase was seen in the volume per void. Twenty out of 30 patients chose to continue solifenacin therapy after termination of the study. The majority of patients reported global QoL improvement.Conclusions. Solifenacin is effective in the treatment of MS patients with OAB symptoms. This is the first study with solifenacin in a specific neurogenic patient group with a neurogenic disease-specific QoL outcome measure (MS-QoL 54).

Thermal ablation of saphenous veins is feasible and safe in patients older than 75 years: A prospective study (EVTA study)

2014 ◽  
Vol 30 (8) ◽  
pp. 525-532 ◽  
Author(s):  
C Hamel-Desnos ◽  
P Desnos ◽  
F-A Allaert ◽  
P Kern ◽  
Keyword(s):  
Side Effects ◽  
Prospective Study ◽  
Thermal Ablation ◽  
Cardiac Insufficiency ◽  
Control Group ◽  
Saphenous Veins ◽  
Group 2 ◽  
Multicenter Prospective Study ◽  
A Prospective Study ◽  
Group 1

Objectives To investigate the tolerance and safety of thermal ablation (TA), consisting of radiofrequency or endovenous laser (EVLA) of saphenous veins (SV) in elderly (group 1 ≥75 years), compared with a control group (group 2 <75 years). Method An Observational multicenter-prospective study was conducted, under the aegis of the French and Swiss Societies of Phlebology (18 centers). Ninety patients were included in group 1, 617 in group 2 (mean age 80 years and 53 years; 69% women in both groups), representing 863 SV. Mean trunk diameters were similar in both groups (small SV: 6 mm; great SV: 7 mm). In group 1, comorbidities were more frequent, particularly cardiac insufficiency, diabetes, history of thrombosis, and CEAP clinical class was significantly higher. Results EVLA was used in 86% of cases. Settings used were similar in both groups for each technique. Only 6% of TA was performed in an operating room for group 1 (14% group 2). Tumescent local anaesthesia (TLA) alone was used in 91% of cases in group 1 (85% group 2). The mean pain score was only 1.6 for the procedure itself (VASP 0–10; 10 max.) and 1.4 for the 10 days following the procedure. Side effects were few, but rate of paraesthesia was higher when general anaesthesia was used (11.8%) compared with TLA alone (2.2%). At three months, 100% of SV was occluded in group 1 (99.5% group 2), with high satisfaction score (9.3/10). Conclusion TA is safe and effective in elderly; it should be performed strictly under TLA to minimize side effects.

Final results of a prospective study of scalp cooling in preventing chemotherapy-induced alopecia

2019 ◽  
Vol 15 (29) ◽  
pp. 3337-3344
Author(s):  
Laura Orlando ◽  
Dario Loparco ◽  
Palma Fedele ◽  
Paola Schiavone ◽  
Annamaria Quaranta ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Prospective Study ◽  
Cancer Patients ◽  
Early Breast Cancer ◽  
Scalp Cooling ◽  
Efficacy And Safety ◽  
Breast Cancer Patients ◽  
Cancer Treatments ◽  
A Prospective Study

Aim: Alopecia is a distressing effect of cancer treatments. Our study examined efficacy and safety of scalp cooling to prevent chemotherapy-induced alopecia. Materials & methods: Early breast cancer patients candidate to anthracycline and/or taxane were eligible. Dean's alopecia scale was used to classify alopecia. Results: From February 2016 to November 2018, 127 women were enrolled; 55 (43.3%) received epirubicin/cyclophosphamide (4 EC 3 weeks) followed by paclitaxel (12 P weeks); 50 (39.4%) received 4 EC 3 weeks; 20 (15.7%) received 12 P weeks/trastuzumab and 2 docetaxel/cyclophosphamide (4 TC 3 weeks). The success rate was 71.7% (G0 21.3%, G1 31.5%, G2 18.9%). Frequent side effects were: coldness, headache, scalp pain and head heaviness. Conclusion: In our study, scalp cooling can prevent alopecia thus supporting the wider use in early breast cancer.

Role of routine fluid replacement in children undergoing tonsillectomy

1990 ◽  
Vol 104 (10) ◽  
pp. 801-802 ◽  
Author(s):  
P. S. Wilson ◽  
D. G. Snow ◽  
J. O'Connel ◽  
D. W. Proops ◽  
M. Barrow
Keyword(s):  
Blood Loss ◽  
Prospective Study ◽  
Intravenous Infusion ◽  
Intravenous Fluid ◽  
Fluid Replacement ◽  
Control Group ◽  
A Prospective Study ◽  
To Receive

AbstractIt has been suggested that children undergoing tonsillectomy would benefit from an intravenous infusion, to counteract the period of pre-operativefasting combined with the blood loss at operation.A prospective study of 50 children undergoing tonsillectomy was undertaken. The children were randomly allocated into two groups, one to receive an infusion and a control group.There were no significant differences between the two groups, although the children with an infusion had a longer mean post-operative stay.There would seem to be no role for routine intravenous fluid replacement in children undergoing uncomplicated tonsillectomy.

A prospective study of elderly initiating mirabegron versus antimuscarinics: Patient reported outcomes from the Overactive Bladder Satisfaction Scales and other instruments

2017 ◽  
Vol 37 (1) ◽  
pp. 177-185 ◽  
Author(s):  
Suvapun Bunniran ◽  
Cralen Davis ◽  
Rita Kristy ◽  
Daniel Ng ◽  
Carol R. Schermer ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Prospective Study ◽  
Patient Reported Outcomes ◽  
Patient Reported ◽  
A Prospective Study

scholarly journals Treatment of Diabetic Foot Infections: A Prospective Study Highlighting the Efficacy and Safety of Moxifloxacin

2018 ◽  
Vol 8 (2-3) ◽  
pp. 32-36 ◽  
Author(s):  
Bikha Ram Devrajani ◽  
Samar Raza ◽  
Rubina Khushik ◽  
Syed Zulfiquar Ali Shah ◽  
Sanam Mari ◽  
...  
Keyword(s):  
Prospective Study ◽  
Diabetic Foot ◽  
Efficacy And Safety ◽  
Diabetic Foot Infections ◽  
A Prospective Study

A Prospective Study Evaluating the Role of Homemade Yogurt as a Treatment Option for Irritable Bowel Disease

2017 ◽  
Vol 112 ◽  
pp. S238-S239
Author(s):  
Manju Girish Chandran ◽  
Resmi Varghese ◽  
Anoop Jose Thoppil ◽  
Marina Joseph ◽  
Thomas Augustine ◽  
...  
Keyword(s):  
Prospective Study ◽  
Treatment Option ◽  
Bowel Disease ◽  
Irritable Bowel Disease ◽  
Irritable Bowel ◽  
A Prospective Study
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