scholarly journals Central nervous system depressant effect of hot water extract of Ocimum sanctum Linn. (Labiateae)

2002 ◽  
Vol 2 (2) ◽  
pp. 101-105
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Water Extract ◽  
Hot Water ◽  
Ocimum Sanctum ◽  
Depressant Effect ◽  
Hot Water Extract ◽  
Central Nervous System Depressant

scholarly journals Importance of Herba Passiflorae in Medicinal Applications: Review on Experimental and Clinical Pharmacology

2021 ◽  
Vol 11 (5) ◽  
pp. 12886-12900
Keyword(s):  
Central Nervous System ◽  
Clinical Pharmacology ◽  
Nervous System ◽  
Water Extract ◽  
Passion Fruit ◽  
Aerial Parts ◽  
Experimental Pharmacology ◽  
Sedative Effects ◽  
Central Nervous System Depressant ◽  
Anti Inflammatory

The dried aerial parts of Passiflora incarnate L. plant are called Herba Passiflorae. This plant belongs to the Passifloraceae family. This review aims to focus on the importance of Herba Passiflorae in medicinal applications with special reference to its experimental and clinical pharmacology. Herba Passiflorae possesses flavonoids and alkaloids ingredients. The major constituents of Herba Passiflorae are flavonoids such as vicenin-2, orientin, isoorientin, vitexin, and isovitexin. Herba Passiflorae is applied for the cure of dysmenorrhoea, neuralgia, and nervous tachycardia. It is a slight sedative for nervous restlessness, insomnia, and anxiety. The fruit of Herba Passiflorae is used for jams, jellies, and desserts. The juice is a favorite flavoring in drinks. The pharmacology effect of Herba Passiflorae includes experimental and clinical pharmacology. Experimental pharmacology includes analgesic, antipyretic, anti-inflammatory, antimicrobial, cardiovascular, central nervous system depressant, and uterine stimulant effects. Clinical pharmacology includes anxiolytic, analgesic, and sedative effects, as well as its effect on nausea, menopause, dysmenorrhea, and diabetes. Herba Passiflorae stimulates uterine contractions, so it is used during pregnancy. The water extract of Herba Passiflorae is not genotoxic. The passion fruit is more appropriate for children's use due to the incorporation of Lactobacillus casei in passion fruit. The daily oral intake of passion fruit at public doses is non-toxic and safe. The daily dose in adults as a sedative is 0.5-2 g of aerial parts 3-4 times. In conclusion, Herba Passiflorae has analgesic, antipyretic, anti-inflammatory, antimicrobial, cardiovascular, central nervous system depressant, uterine stimulant, anxiolytic, analgesic, and sedative effects, as well as, its effect on nausea, menopause, dysmenorrhea, and diabetes.

scholarly journals Preliminary study on the central nervous system depressant effect of Picrorhiza kurrooa Royle. (Scrophulariaceae) in mice models

2008 ◽  
Vol 8 (4) ◽  
pp. 448-451 ◽  
Author(s):  
Tasmina Rahman ◽  
Khandaker Ashfaqur Rahman ◽  
Sultana Rajia ◽  
Mahiuddin Alamgir ◽  
Mahmud Tareq Hassan Khan ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Depressant Effect ◽  
Picrorhiza Kurrooa ◽  
Central Nervous System Depressant ◽  
The Central Nervous System ◽  
Preliminary Study

scholarly journals Evaluation of Analgesic and Central Nervous System Depressant Effects of Holarrhena antidysenterica Stem on Swiss Albino Mice Model

2018 ◽  
Vol 20 (2) ◽  
pp. 205-212 ◽  
Author(s):  
Md Anamul Haque ◽  
Md Anwarul Haque ◽  
Md Anwar Ul Islam
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Open Field ◽  
Biological Activities ◽  
Pharmaceutical Journal ◽  
Depressant Effect ◽  
Mice Model ◽  
Cns Depressant ◽  
Holarrhena Antidysenterica ◽  
Central Nervous System Depressant

Plants are astonishing reservoir of bioactive natural compounds; many of these are able to exhibit outstanding biological activities in animals. Holarrhena antidysenterica is widely used as a traditional medicine. Aim of the present study was to investigate the possible analgesic and central nervous system (CNS) depressant effects of methanol (MHAS), petroleum ether (PHAS), chloroform (CHAS), dichloromethane (DHAS) and aqueous (AHAS) extracts of the H. antidysenterica stem. The analgesic effect was evaluated by acetic acid induced writhing and hot plate methods at 50 and 100 mg/kg dose. The CNS-depressant effect was assessed by using open field, hole cross and head deep tests at 100 and 200 mg/kg dose. All the extracts had exhibited significant (Pb < 0.01, Pa < 0.001) analgesic and CNS depressant effects at dose dependant manner. CHAL showed maximum analgesic and CNS-depressant effect. It had shown 71.34% inhibition of abdominal writhing and 70.39% elongation of paw licking time at 100mg/kg dose. In CNS-depressant study, it exhibited 88.51% inhibition in open field (locomotion), 83.20% inhibition in hole cross (locomotion) and 85.15% inhibition (head deeping) in head deep test at 200mg/kg dose. Among the five extracts CHAL is a potent analgesic and CNSdepressant agent.Bangladesh Pharmaceutical Journal 20(2): 205-212, 2017

Effects of a Hot-Water Extract of Trametes versicolor (L.: Fr.) Lloyd (Aphyllophoromycetideae) on the Recovery of Rat Liver Function

2000 ◽  
Vol 2 (1) ◽  
pp. 7
Author(s):  
Byong Kak Kim ◽  
Sang Eun Park ◽  
So Young Kim ◽  
Jin Won Hyun ◽  
Ha Won Kim ◽  
...  
Keyword(s):  
Liver Function ◽  
Rat Liver ◽  
Trametes Versicolor ◽  
Water Extract ◽  
Hot Water ◽  
Hot Water Extract
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