scholarly journals Synergistic growth inhibitory effects of Phyllanthus emblica and Terminalia bellerica extracts with conventional cytotoxic agents: Doxorubicin and cisplatin against human hepatocellular carcinoma and lung cancer cells

2008 ◽  
Vol 14 (10) ◽  
pp. 1491 ◽  
Author(s):  
Khosit Pinmai ◽  
Sriharut Chunlaratthanabhorn ◽  
Chatri Ngamkitidechakul ◽  
Noppamas Soonthornchareon ◽  
Chariya Hahnvajanawong
Keyword(s):  
Lung Cancer ◽  
Hepatocellular Carcinoma ◽  
Cancer Cells ◽  
Human Hepatocellular Carcinoma ◽  
Cytotoxic Agents ◽  
Lung Cancer Cells ◽  
Phyllanthus Emblica ◽  
Inhibitory Effects ◽  
Terminalia Bellerica ◽  
Growth Inhibitory

Discovery of a novel fluorescent HSP90 inhibitor and its anti-lung cancer effect

RSC Advances ◽  
2014 ◽  
Vol 4 (38) ◽  
pp. 19887-19890 ◽  
Author(s):  
Su-Yun Bai ◽  
Xi Dai ◽  
Bao-Xiang Zhao ◽  
Jun-Ying Miao
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Hsp90 Inhibitor ◽  
Lung Cancer Cells ◽  
Inhibitory Effects ◽  
Strong Growth ◽  
Growth Inhibitory

A novel fluorescent HSP90 inhibitor with strong growth inhibitory effects on lung cancer cells was developed.

scholarly journals Growth inhibitory effects of miR‐221 and miR‐222 in non‐small cell lung cancer cells

2015 ◽  
Vol 4 (4) ◽  
pp. 551-564 ◽  
Author(s):  
Ryo Yamashita ◽  
Mitsuo Sato ◽  
Tomohiko Kakumu ◽  
Tetsunari Hase ◽  
Naoyuki Yogo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
Inhibitory Effects ◽  
Small Cell Lung ◽  
Growth Inhibitory

Inhibitory effects of Actinidia Chinensis planch root extracts (acRoots) on human lung cancer cells through retinoic acid receptor beta

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Lingyan Wang ◽  
Jiayun Hou ◽  
Minghuan Zheng ◽  
Lin Shi
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Human Lung ◽  
Retinoic Acid Receptor ◽  
Lung Cancer Cells ◽  
Human Lung Cancer ◽  
Inhibitory Effects ◽  
The Core ◽  
Human Lung Cancer Cells ◽  
Receptor Beta

Actinidia Chinensis Planch roots (acRoots) are used to treat many cancers, although the anti-tumor mechanism by which acRoots inhibit cancer cell growth remains unclear. The present study aims at investigating inhibitory effects of acRoots on human lung cancer cells and potential mechanisms. Our data demonstrate that the inhibitory effects of acRoots on lung cancer cells depend on genetic backgrounds and phenotypes of cells. We furthermore found the expression of metabolism-associated gene profiles varied between acRoots-hypersensitive (H460) or hyposensitive lung cancer cells (H1299) after screening lung cancer cells with different genetic backgrounds. We selected retinoic acid receptor beta (RARB) as the core target within metabolism-associated core gene networks and evaluated RARB changes and roles in cells treated with acRoots at different concentrations and timeframes. Hypersensitive cancer cells with the deletion of RARB expression did not response to the treatment with acRoots, while RARB deletion did not change effects of acRoots on hyposensitive cells. Thus, it seems that RARB as the core target within metabolism-associated networks plays important roles in the regulation of lung cancer cell sensitivity to acRoots.

Apoptosis-inducing effects and growth inhibitory of a novel chalcone, in human hepatic cancer cells and lung cancer cells

2018 ◽  
Vol 105 ◽  
pp. 195-203 ◽  
Author(s):  
Naiwei Dong ◽  
Xin Liu ◽  
Tong Zhao ◽  
Lei Wang ◽  
Huimin Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Hepatic Cancer ◽  
Growth Inhibitory
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