Impact of Cervical Infection with Bacteria Ureaplasma Urealyticum to Interleukin-1α-Expression in Pregnant Women

2020 ◽  
Vol 11 (2) ◽  
pp. 1006
Author(s):  
Aimen A. Ahmed ◽  
Sabah M. Salih ◽  
Ayoub A. Bazzaz
Keyword(s):  
Pregnant Women ◽  
Ureaplasma Urealyticum ◽  
Cervical Infection ◽  
Interleukin 1Α

Cost-Effectiveness of with Rapid-Test Etiological vs. Syndromic Diagnosis in Non-Pregnant Women with Symptoms of Cervical Infection

2012 ◽  
Author(s):  
Javier Díaz Rojas ◽  
Mario García Molina ◽  
Liliana Chicaíza ◽  
Alexander Moreno Calderón ◽  
Víctor Prieto Martínez ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Pregnant Women ◽  
Rapid Test ◽  
Cervical Infection ◽  
Syndromic Diagnosis

scholarly journals Prevalence and Antibiotic Susceptibility of Mycoplasma hominis and Ureaplasma urealyticum in Pregnant Women

2016 ◽  
Vol 57 (5) ◽  
pp. 1271 ◽  
Author(s):  
Min Young Lee ◽  
Myeong Hee Kim ◽  
Woo In Lee ◽  
So Young Kang ◽  
You La Jeon
Keyword(s):  
Pregnant Women ◽  
Antibiotic Susceptibility ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis

SEROTYPE DISTRIBUTION OF UREAPLASMA UREALYTICUM IN INFERTILE AND PREGNANT WOMEN

1986 ◽  
Vol 5 (Supplement) ◽  
pp. S348
Author(s):  
J. Lefebvre ◽  
L. Granger ◽  
P. St.-Michel ◽  
G. Faucher ◽  
P. Miron
Keyword(s):  
Pregnant Women ◽  
Ureaplasma Urealyticum ◽  
Serotype Distribution

scholarly journals Interleukin-1 Receptor Antagonist Gene Polymorphism, Vaginal Interleukin-1 Receptor Antagonist Concentrations, and Vaginal Ureaplasma urealyticum Colonization in Pregnant Women

2003 ◽  
Vol 71 (1) ◽  
pp. 271-274 ◽  
Author(s):  
Parrin T. Barton ◽  
Stefan Gerber ◽  
Daniel W. Skupski ◽  
Steven S. Witkin
Keyword(s):  
Pregnant Women ◽  
Receptor Antagonist ◽  
Ureaplasma Urealyticum ◽  
Interleukin 1 ◽  
First Trimester ◽  
Enzyme Linked Immunosorbent Assay ◽  
Interleukin 1 Receptor Antagonist ◽  
First Trimester Of Pregnancy ◽  
The Relationship ◽  
Uneventful Pregnancy

ABSTRACT Ureaplasma urealyticum is the microorganism most frequently isolated from amniotic fluids of women in preterm labor. The relationship between vaginal colonization with U. urealyticum, vaginal interleukin-1 receptor antagonist (IL-1ra) levels, and the IL-1ra genotype in pregnant women was examined. Vaginal specimens, obtained with a cotton swab from 207 women in their first trimester of pregnancy, were tested for IL-1ra concentrations by enzyme-linked immunosorbent assay and for U. urealyticum and IL-1ra genotypes by PCR. U. urealyticum was detected in 85 (41.1%) women. The median IL-1ra level was 450 ng/ml in women positive for U. urealyticum, as opposed to 225 ng/ml in women negative for this microorganism (P < 0.0001). Sixty-two percent of the 16 women who were homozygous for allele 2 of the IL-1ra gene (IL-1RN*2) were colonized with U. urealyticum, as opposed to 47% of the 49 women who were IL-1RN*1/IL-1RN*2 heterozygotes and 34% of the 133 women who were IL-1RN*1 homozygotes (P < 0.05). Median IL-1ra levels were 750 ng/ml in IL-1RN*2 homozygotes, 300 ng/ml in IL-1RN*1/IL-1RN*2 heterozygotes, and 250 ng/ml in IL-1RN*1 homozygotes (P = 0.02). The vast majority of subjects had an uneventful pregnancy and delivered a healthy infant at term. The IL-1ra genotype or U. urealyticum colonization was unrelated to birth weight. Pregnant women who are colonized with U. urealyticum during the first trimester have elevated vaginal IL-1ra concentrations and a higher prevalence of the IL-1RN*2 homozygote genotype than do noncolonized women.

scholarly journals UROGENITAL MYCOPLASMA ROLE IN REPRODUCTIVE PATHOLOGIES

2017 ◽  
Vol 1 (65) ◽  
pp. 71-76 ◽  
Author(s):  
Ольга Островская ◽  
Olga Ostrovskaya ◽  
Марина Власова ◽  
Marina Vlasova ◽  
Ольга Кожарская ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Preterm Delivery ◽  
Detection Rate ◽  
Ureaplasma Urealyticum ◽  
Recurrent Miscarriage ◽  
Mycoplasma Hominis ◽  
Mycoplasma Genitalium ◽  
Tissue Samples ◽  
Mycoplasma Detection ◽  
Genital Mycoplasmas

The objective of the research was to study genital mycoplasma contribution to the development of reproductive disorders. Mycoplasma detection rate in genital smears of pregnant women of Khabarovsk was studied by a polymerase chain reaction (PCR) method. Ureaplasma (urealyticum+parvum) was detected in 56.3% of cases; Mycoplasma hominis in 7.5% of cases, Mycoplasma genitalium in 0% of cases. Genital mycoplasmas were detected in chorionic and fetal tissue samples in early-term spontaneous miscarriage cases, suction biopsies in women with recurrent miscarriage, tissue samples in elective abortions, placental samples of women whose pregnancy ended in preterm delivery, and placental samples of women who gave birth to children at term. Ureaplasma (urealyticum+parvum) DNA was detected in 11.9%, 18.8%, 1.4%, 32.6%, and 25.0% of cases, respectively; Mycoplasma hominis DNA in 7.4%, 12.5%, 2.6%, 2.3%, and 0% of cases, respectively; Mycoplasma genitalium DNA in 5.2%, 6.3%, 1.4%, 2.3%, 0%, respectively. Genital mycoplasmas were detected in autopsy material of children who had died in neonatal and postnatal periods. Relationship between mycoplasma concentration in vaginal flora of pregnant women and preterm delivery was identified using real-time PCR. Mycoplasma detection rate in reproductive pathologies was found to be significantly higher than in control groups. The results of the study favor the view of etiopathogenetic role of mycoplasmas in development of complications and outcomes of pregnancy.

scholarly journals Microbiota of fetal membranes in intact amniotic sac and full-term pregnancy

2021 ◽  
pp. 4-11
Author(s):  
M.A. Kaganova ◽  
◽  
N.V Spiridonova ◽  
E.A. Makhlina ◽  
◽  
...  
Keyword(s):  
Pregnant Women ◽  
Ureaplasma Urealyticum ◽  
Bacterial Load ◽  
Full Term ◽  
Gardnerella Vaginalis ◽  
Elective Cesarean Section ◽  
Fetal Membrane ◽  
Fetal Membranes ◽  
Term Pregnancy ◽  
Candida Spp

Aim of research. To study the microbial landscape of intact fetal membranes in full-term pregnancy. Materials and methods. In 19 pregnant women (mean age — 31.0 ± 5.3 years, mean gestational age — 39.3 ± 0.65 weeks) with intact fetal membranes, the fetal membrane tissue was collected during elective cesarean section to detect by polymerase chain reaction the following microorganisms: Lactobacillus spp., Enterobacteriaceae, Streptococcus spp., Staphylococcus spp., Gardnerella vaginalis/Prevotella bivia/Porphyromonas spp., Eubacterium spp., Sneathia spp./Leptotrihia spp./ Fusobacterium spp., Megasphaera spp./Veillonella spp./ Dialister spp., Lachnobacterium spp./Clostridium spp., Mobiluncus spp./Corynebacterium spp., Peptostreptococcus spp., Atopobium vaginae, Mycoplasma hominis, Ureaplasma (urealyticum + parvum), Candida spp., Mycoplasma genitalium. Results. Sterile membranes were found in 5 pregnant women (26.3%), in the remaining cases, the total bacterial load (TBL) was 104.5 (103.5–105.8) genome equivalents (GE) per sample. Representatives of the Enterobacteriaceae family prevailed — 104.5 GE per sample on average, only in one case Candida spp. were detected. In 42.1% of cases, when determining TBL, specific types of microorganisms were not identified. Conclusion. On the fetal membranes in full-term pregnancy, the average TBL corresponding to 104.5 (103.5–105.8) GE per sample, in which Enterobacteriaceae prevail in the amount of 104.5 GE per sample on average, is acceptable.

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