scholarly journals A one-pot catalyst-free synthesis of functionalized pyrrolo[1,2-a]quinoxaline derivatives from benzene-1,2-diamine, acetylenedicarboxylates and ethyl bromopyruvate

2013 ◽  
Vol 9 ◽  
pp. 510-515 ◽  
Author(s):  
Mohammad Piltan ◽  
Loghman Moradi ◽  
Golaleh Abasi ◽  
Seyed Amir Zarei
Keyword(s):  
Multicomponent Reaction ◽  
One Pot ◽  
Dialkyl Acetylenedicarboxylates ◽  
Catalyst Free ◽  
Quinoxaline Derivatives ◽  
Ethyl Bromopyruvate

The catalyst-free multicomponent reaction of 1,2-diaminobenzene, dialkyl acetylenedicarboxylates, and ethyl bromopyruvate forms pyrrolo[1,2-a]quinoxaline derivatives in good yields. Ethylenediamine also reacts under similar conditions to produce new pyrrolo[1,2-a]pyrazine derivatives.

One-Pot Synthesis of Thiazolo[3,4-a]Quinoxalines from 1,2-Diamines, Aryl Isothiocyanates and Ethyl Bromopyruvate

2017 ◽  
Vol 41 (12) ◽  
pp. 712-714 ◽  
Author(s):  
Mohammad Piltan
Keyword(s):  
Chromatographic Separations ◽  
One Pot ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
Wide Range ◽  
Quinoxaline Derivatives ◽  
First Time ◽  
Aryl Isothiocyanates ◽  
Ethyl Bromopyruvate

Some hitherto unreported thiazolo[3,4- a]quinoxaline derivatives have been synthesised in excellent yields via a one-pot, three-component reaction of benzene-1,2-diamines, ethyl bromopyruvate and aryl isothiocyanates in MeCN, for the first time. The protocol avoids the use of any catalysts or chromatographic separations and provides a wide range of novel thiazolo[3,4- a]quinoxalines.

Catalyst free Synthesis of Highly Functionalized Indolizines from In Situ Generated Pyridinium Ylides via One‐Pot Multicomponent Reaction

2019 ◽  
Vol 4 (13) ◽  
pp. 3717-3721 ◽  
Author(s):  
Vediyappan Ramesh ◽  
Natarajan Savitha Devi ◽  
Marappan Velusamy ◽  
Sivakumar Shanmugam
Keyword(s):  
Multicomponent Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
Pyridinium Ylides

Three Component, One‐Pot Synthesis of Multifunctional Quinolinopyranpyrazoles via Catalyst‐Free Multicomponent Reaction

2019 ◽  
Vol 4 (27) ◽  
pp. 7996-7999 ◽  
Author(s):  
Manickam Bakthadoss ◽  
Varathan Vinayagam ◽  
Vishal Agarwal ◽  
Duddu S. Sharada
Keyword(s):  
Multicomponent Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis

An efficient catalyst-free chemoselective multicomponent reaction for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives

RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 24327-24335 ◽  
Author(s):  
Yuvaraj Dommaraju ◽  
Somadrita Borthakur ◽  
Nimmakuri Rajesh ◽  
Dipak Prajapati
Keyword(s):  
Multicomponent Reaction ◽  
Reaction Conditions ◽  
One Pot ◽  
Efficient Catalyst ◽  
Catalyst Free ◽  
High Yields

An efficient catalyst-free, one-pot multicomponent reaction has been developed for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives. The method offers easy and column free separation, mild reaction conditions and high yields.

Efficient assembly of quinoxaline derivatives from benzene-1,2-diamines, dialkyl acetylenedicarboxylates and ninhydrin

2016 ◽  
Vol 22 (1) ◽  
pp. 55-57 ◽  
Author(s):  
Zohreh Sharafi ◽  
Mohammad Piltan
Keyword(s):  
One Pot ◽  
Mild Conditions ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction ◽  
Quinoxaline Derivatives

AbstractThe hitherto unreported, highly functionalized alkyl 2-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)acetate derivatives 4 have been synthesized in excellent yields via a one-pot three-component reaction of benzene-1,2-diamines, dialkyl acetylenedicarboxylates, and ninhydrin under mild conditions.

ChemInform Abstract: A Catalyst Free, One Pot Approach for the Synthesis of Quinoxaline Derivatives via Oxidative Cyclization of 1,2-Diamines and Phenacyl Bromides.

ChemInform ◽  
2015 ◽  
Vol 46 (26) ◽  
pp. no-no
Author(s):  
Kapil Kumar ◽  
Sagar Ravso Mudshinge ◽  
Sandeep Goyal ◽  
Mukesh Gangar ◽  
Vipin A. Nair
Keyword(s):  
Oxidative Cyclization ◽  
One Pot ◽  
Catalyst Free ◽  
Phenacyl Bromides ◽  
Quinoxaline Derivatives

A catalyst free, one pot approach for the synthesis of quinoxaline derivatives via oxidative cyclisation of 1,2-diamines and phenacyl bromides

2015 ◽  
Vol 56 (10) ◽  
pp. 1266-1271 ◽  
Author(s):  
Kapil Kumar ◽  
Sagar Ravso Mudshinge ◽  
Sandeep Goyal ◽  
Mukesh Gangar ◽  
Vipin A. Nair
Keyword(s):  
One Pot ◽  
Catalyst Free ◽  
Phenacyl Bromides ◽  
Quinoxaline Derivatives ◽  
Oxidative Cyclisation

An efficient and catalyst-free synthesis of N-arylidene-2-arylimidazo[1,2-a]pyridine-3-ylamine derivatives via Strecker reaction under controlled microwave heating

2017 ◽  
Vol 6 (4) ◽  
Author(s):  
Afaf Mohamed Abdel Hameed ◽  
Moustafa Sherief Moustafa ◽  
Saleh Mohammed Al-Mousawi ◽  
Reham R. Awed ◽  
Kamal Usef Sadek
Keyword(s):  
Microwave Heating ◽  
Multicomponent Reaction ◽  
Aromatic Aldehydes ◽  
Atom Economy ◽  
One Pot ◽  
Strecker Reaction ◽  
Catalyst Free ◽  
Benzoyl Cyanide

AbstractAn efficient one-pot multicomponent reaction of 2-aminopyridine with aromatic aldehydes and either benzoyl cyanide or cyanamide in pyridine under controlled microwave heating afforded N-aryldene-2-arylimidazo[1,2-a]-pyridine-3-ylamine derivatives. The reaction is catalyst free and is of high atom economy.

Metal-Free Photoinduced Hydroalkylation Cascade Enabled by an Electron-Donor-Acceptor Complex

2020 ◽  
Author(s):  
José Tiago Menezes Correia ◽  
Gustavo Piva da Silva ◽  
Camila Menezes Kisukuri ◽  
Elias André ◽  
Bruno Pires ◽  
...  
Keyword(s):  
Electron Donor ◽  
Functional Group ◽  
Photoexcited Electron ◽  
One Pot ◽  
Quaternary Centers ◽  
Metal Free ◽  
Acceptor Complex ◽  
Catalyst Free ◽  
Donor Acceptor ◽  
Radical Cascade

A metal- and catalyst-free photoinduced radical cascade hydroalkylation of 1,7-enynes has been disclosed. The process is triggered by a SET event involving a photoexcited electron-donor-aceptor complex between NHPI ester and Hantzsch ester, which decomposes to afford a tertiary radical that is readily trapped by the enyne. <a>The method provides an operationally simple, robust and step-economical approach to the construction of diversely functionalized dihydroquinolinones bearing quaternary-centers. A sequential one-pot hydroalkylation-isomerization approach is also allowed giving access to a family of quinolinones. A wide substrate scope and high functional group tolerance was observed in both approaches</a>.

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