scholarly journals P53 Protein Expression in Epithelial Lining of Odontogenic Cysts: An Immunohistochemical Descriptive Case Study

2021 ◽  
Vol 8 (3) ◽  
pp. 29-34
Author(s):  
Aneela Amjad ◽  
Aqib Sohail ◽  
Nighat Zahid ◽  
Asad Chatta ◽  
Nauman Rauf Khan ◽  
...  
Keyword(s):  
Protein Expression ◽  
P53 Protein ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Odontogenic Cysts ◽  
Keratocystic Odontogenic Tumor ◽  
Epithelial Lining ◽  
Descriptive Case Study ◽  
P53 Protein Expression

OBJECTIVES: The current study was conducted to analyze immunohistochemical appearance of P53 protein in odontogenic cysts. METHODOLOGY: Thirty paraffin blocks of confirmed case were prepared to investigate the immunohistochemical appearance of P53 protein. RESULTS: Sixteen out of thirty odontogenic cysts (53.3%) showed P53, four out of ten dentigerous cyst (40%) had P53, twelve out of fifteen odontogenic keratocysts (80%) expressed P53 while none of the five radicular cysts (0%) showed P53 protein. CONCLUSION: Reclassification of OKC as keratocystic odontogenic tumor was supported by the present study and its findings.  

scholarly journals A Clinicopathological Report of Four Cases of Squamous Odontogenic Tumor-Like Proliferations in Odontogenic Cysts: Suggested Opinions regarding This Unusual Nature

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Massoumeh Zargaran ◽  
Setareh Shojaei
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Odontogenic Cysts ◽  
Epithelial Lining ◽  
Epithelial Cyst ◽  
Effective Role ◽  
Well Differentiated ◽  
Cyst Lining

Distinguishing squamous odontogenic tumor-like proliferations (SOTLPs) is important in odontogenic cysts to avoid misinterpretation such as a squamous odontogenic tumor, well-differentiated squamous cell carcinoma, and acanthomatous type of ameloblastoma. This study is aimed at reporting 4 cases of these clinicopathological proliferations in order to shed more light on the importance of distinguishing them from other similar types. 150 odontogenic cysts were studied in which four cases (2.66%) with SOTLPs were identified including 2 radicular cysts, 1 dentigerous cyst, and 1 odontogenic keratocyst. These proliferations were observed in the cysts’ wall particularly adjacent to the epithelial lining. All cysts had inflammation while 3 cases showed budding from the epithelial cyst lining. The findings suggested that lining of odontogenic cysts could be a source of SOTLPs, and inflammation probably played an effective role in their development. Its incidence was 2.66% in the present study. Although SOTLPs are not frequent in odontogenic cysts, their identification is important to prevent wrong histopathologic interpretation and treatment.

p53 Protein Expression in Odontogenic Cysts

2001 ◽  
Vol 27 (7) ◽  
pp. 459-461 ◽  
Author(s):  
A PIATTELLI ◽  
M FIORONI ◽  
A SANTINELLI ◽  
C RUBINI
Keyword(s):  
Protein Expression ◽  
P53 Protein ◽  
Odontogenic Cysts ◽  
P53 Protein Expression

scholarly journals 54 Prognostic value of p53 protein expression in breast cancer

2020 ◽  
Author(s):  
S Ben Slama ◽  
D Bacha ◽  
A Ben Amor ◽  
A Halouani ◽  
A Lahmar
Keyword(s):  
Breast Cancer ◽  
Protein Expression ◽  
Prognostic Value ◽  
P53 Protein ◽  
P53 Protein Expression

p53 protein expression in sequential biopsies of oral dysplasias and in situ carcinomas

1995 ◽  
Vol 24 (1) ◽  
pp. 18-22 ◽  
Author(s):  
J. A. Regezi ◽  
R. J. Zarbo ◽  
E. Regev ◽  
S. Pisanty ◽  
S. Silverman ◽  
...  
Keyword(s):  
Protein Expression ◽  
P53 Protein ◽  
P53 Protein Expression
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