scholarly journals Biochemical Measurement of Neonatal Hypoxia

10.3791/2948 ◽  
2011 ◽  
Author(s):  
Megan S. Plank ◽  
Teleka C. Calderon ◽  
Yayesh Asmerom ◽  
Danilo S. Boskovic ◽  
Danilyn M. Angeles
Keyword(s):  
Neonatal Hypoxia ◽  
Biochemical Measurement

Serum Vitamin B12 Concentrations among Mothers and Newborns and Follow-up Study to Assess Implication on the Growth Velocity and the Urinary Methylmalonic Acid Excretion

2009 ◽  
Vol 79 (56) ◽  
pp. 297-307 ◽  
Author(s):  
Laila Hussein ◽  
Sahar Abdel Aziz ◽  
Salwa Tapouzada ◽  
Boehles
Keyword(s):  
Early Diagnosis ◽  
Growth Velocity ◽  
Methylmalonic Acid ◽  
Post Partum ◽  
Serum Vitamin ◽  
Vitamin B ◽  
Postnatal Life ◽  
Negative Consequences ◽  
Metabolic Marker ◽  
Biochemical Measurement

Objective:Cobalamin (B12) deficiency has been reported in infants born to mothers with low cobalamin intake. Early diagnosis of vitamin B12 deficiency in infants is critical for the prevention of neurobehavioral disorders. We investigated the relationship between serum vitamin B12 level in newborns and in their healthy mothers who consumed an omnivorous diet. Anthropometry was studied longitudinally to assess the growth velocity of the infants. Urinary methylmalonic acid (MMA) excretion of 6-month old infants was compared retrospectively as the biomarker correlated with the initial serum vitamin B12 concentrations. Methods: Serum cobalamin and blood hemoglobin were determined in 84 pairs of newborns and their mothers. Urinary MMA excretion was measured in the same subjects during the first 6 months of the post partum period. Results: At birth, median serum cobalamin levels were 152.0 pmol/L in the mothers and 296.6 pmol/L in the newborns. Maternal and neonatal serum cobalamin levels had no effect on growth velocity during the first six months of postnatal life. Serum maternal and neonatal cobalamin levels were inversely associated with urinary MMA excretion. Conclusion: Early diagnosis of vitamin B12 status in neonates and infants is crucial, particularly in nutritionally deprived areas. Biochemical measurement of plasma cobalamin or its metabolic marker MMA is highly recommended. Urinary MMA measurement in cobalamin diagnostics provides an advantage in that blood sampling is not required. A vitamin B12 taskforce should be created to alleviate vitamin deficiency and its negative consequences.

Doublecortin in the Cerebrospinal Fluid Is a Candidate Biomarker of Neurogenesis after Neonatal Hypoxia Ischemia Brain Injury in Rats

2015 ◽  
Vol 76 (S 01) ◽  
Author(s):  
C. Bregere ◽  
U. Fisch ◽  
S. Lieb ◽  
M. Sailer ◽  
L. Chicha ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Brain Injury ◽  
Neonatal Hypoxia ◽  
Hypoxia Ischemia

Quantitative Radioisotope Measurement of Duodenogastric Reflux in Patients with Ulcer or Gastrectomized for Ulcer

1985 ◽  
Vol 24 (03) ◽  
pp. 107-110
Author(s):  
M. Pääkkönen ◽  
S. Aukee ◽  
K. Korhonen ◽  
A. Pääkkönen ◽  
E. Länsimies ◽  
...  
Keyword(s):  
Gamma Camera ◽  
Background Activity ◽  
Bile Reflux ◽  
Duodenogastric Reflux ◽  
Upper Limit ◽  
Visual Evidence ◽  
Biochemical Measurement

SummaryIn this work the duodenogastric reflux was quantified as the amount of radioactivity entering the stomach after an i.v. administration of 99mmTc-HIDA in ulcer patients and in patients who had undergone BI gastrectomy. The results were compared with visual evidence of gastric activity in the gamma camera images and biochemical determination of gastric bile reflux. The method is useful in quantifying the reflux if the activity is above the background activity. It allows the determination of an upper limit for the reflux when the reflux is evident visually. Only two or three images are needed for the quantitation. No correlation was found between biochemical measurement of fasting bile reflux in the stomach and radioisotopic quantification.

Brain damage caused by neonatal hypoxia-ischemia and the effects of hypothermia in severe combined immunodeficient (SCID) mice

2021 ◽  
Vol 337 ◽  
pp. 113577
Author(s):  
Yuko Ogawa ◽  
Emi Tanaka ◽  
Yoshiaki Sato ◽  
Masahiro Tsuji
Keyword(s):  
Brain Damage ◽  
Scid Mice ◽  
Neonatal Hypoxia ◽  
Hypoxia Ischemia

scholarly journals PS-159 Beta-amyloid And S100b Could Be Valuable Biomarkers After Neonatal Hypoxia-reoxygenation. A Study In Newborn Pigs

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A168.2-A168
Author(s):  
T Benterud ◽  
L Pankratov ◽  
R Solberg ◽  
OD Saugstad ◽  
A Skinningsrud ◽  
...  
Keyword(s):  
Beta Amyloid ◽  
Neonatal Hypoxia ◽  
Newborn Pigs ◽  
Hypoxia Reoxygenation

scholarly journals Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

Autophagy ◽  
2010 ◽  
Vol 6 (3) ◽  
pp. 366-377 ◽  
Author(s):  
Silvia Carloni ◽  
Silvia Girelli ◽  
Claudia Scopa ◽  
Giuseppe Buonocore ◽  
Mariangela Longini ◽  
...  
Keyword(s):  
Neuroprotective Effect ◽  
Neonatal Hypoxia ◽  
Hypoxia Ischemia

scholarly journals The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia-ischemia as potently as erythropoietin

2004 ◽  
Vol 91 (4) ◽  
pp. 900-910 ◽  
Author(s):  
Xiaoyang Wang ◽  
Changlian Zhu ◽  
Xinhua Wang ◽  
Jens Gammeltoft Gerwien ◽  
Andre Schrattenholz ◽  
...  
Keyword(s):  
Neonatal Hypoxia ◽  
Hypoxia Ischemia

scholarly journals Splenic Immune Cells in Experimental Neonatal Hypoxia–Ischemia

2012 ◽  
Vol 4 (2) ◽  
pp. 208-219 ◽  
Author(s):  
Nancy Fathali ◽  
Robert P. Ostrowski ◽  
Yu Hasegawa ◽  
Tim Lekic ◽  
Jiping Tang ◽  
...  
Keyword(s):  
Immune Cells ◽  
Neonatal Hypoxia ◽  
Hypoxia Ischemia

Erythrocyte ATP (iATP) as an Indicator of Neonatal Hypoxia

1989 ◽  
pp. 345-352 ◽  
Author(s):  
Felícitas A. Mateos ◽  
Juan G. Puig ◽  
Teresa H. Ramos ◽  
Ramón H. Carranza ◽  
María E. Miranda ◽  
...  
Keyword(s):  
Neonatal Hypoxia
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