scholarly journals Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy

Author(s):  
Andreas Reif ◽  
Anass Chiki ◽  
Jonathan Ricci ◽  
Hilal A. Lashuel
Keyword(s):  
2019 ◽  
Vol 16 (11) ◽  
pp. 898-905
Author(s):  
Harun Patel ◽  
Rahul Pawara ◽  
Sanjay Surana

Quinazoline is the six-membered heterocyclic ring system reported for its versatile biological activities. This characteristic feature of quinazoline makes it a good template for a lead generation library. Ring opening is one of the major concerns in the synthesis of quinazolin-4(3H)-one that results in diamide formation. Here, alternative fusion strategy is reported, which is a time-saving and costeffective method to overcome the ring opening problem associated with the synthesis of benzo[ d][1,3]oxazin-4-one and quinazolin-4(3H)-one.


Author(s):  
Jihyeon Kim ◽  
Heechan Kim ◽  
Sechan Lee ◽  
Giyun Kwon ◽  
Taewon Kang ◽  
...  

A new bipolar-type redox-active organic material with a wide HOMO–LUMO energy gap is designed though the ‘p–n fusion’ strategy.


IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 18318-18325
Author(s):  
Xi Cai ◽  
Xinyue Liu ◽  
Mingyue An ◽  
Guang Han

2021 ◽  
Vol 13 (3) ◽  
pp. 433
Author(s):  
Junge Shen ◽  
Tong Zhang ◽  
Yichen Wang ◽  
Ruxin Wang ◽  
Qi Wang ◽  
...  

Remote sensing images contain complex backgrounds and multi-scale objects, which pose a challenging task for scene classification. The performance is highly dependent on the capacity of the scene representation as well as the discriminability of the classifier. Although multiple models possess better properties than a single model on these aspects, the fusion strategy for these models is a key component to maximize the final accuracy. In this paper, we construct a novel dual-model architecture with a grouping-attention-fusion strategy to improve the performance of scene classification. Specifically, the model employs two different convolutional neural networks (CNNs) for feature extraction, where the grouping-attention-fusion strategy is used to fuse the features of the CNNs in a fine and multi-scale manner. In this way, the resultant feature representation of the scene is enhanced. Moreover, to address the issue of similar appearances between different scenes, we develop a loss function which encourages small intra-class diversities and large inter-class distances. Extensive experiments are conducted on four scene classification datasets include the UCM land-use dataset, the WHU-RS19 dataset, the AID dataset, and the OPTIMAL-31 dataset. The experimental results demonstrate the superiority of the proposed method in comparison with the state-of-the-arts.


2021 ◽  
Vol 16 (4) ◽  
Author(s):  
Bo Wang ◽  
Li Hu ◽  
Bowen Wei ◽  
Zitong Kang ◽  
Chongyi Li

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