Synergistic effects of histone deacetylase inhibitor in combination with mTOR inhibitor in the treatment of prostate carcinoma

Mtor Inhibitor ◽

Synergistic Effects ◽

Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma

Journal of Hematology & Oncology ◽

10.1186/1756-8722-6-53 ◽

2013 ◽

Vol 6 (1) ◽

pp. 53 ◽

Cited By ~ 38

Author(s):

Li Dong ◽

Shu Cheng ◽

Zhong Zheng ◽

Li Wang ◽

Yang Shen ◽

...

Keyword(s):

Cell Death ◽

Histone Deacetylase ◽

Mtor Inhibitor ◽

Autophagic Cell Death ◽

Synergistic Effects of Sodium Butyrate, a Histone Deacetylase Inhibitor, on Increase of Neurogenesis Induced by Pyridoxine and Increase of Neural Proliferation in the Mouse Dentate Gyrus

Neurochemical Research ◽

10.1007/s11064-011-0503-5 ◽

2011 ◽

Vol 36 (10) ◽

pp. 1850-1857 ◽

Cited By ~ 21

Author(s):

Dae Young Yoo ◽

Woosuk Kim ◽

Sung Min Nam ◽

Dae Won Kim ◽

Jin Young Chung ◽

...

Keyword(s):

Dentate Gyrus ◽

Histone Deacetylase ◽

Sodium Butyrate ◽

Synergistic Effects ◽

Superior efficacy of co-treatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC

Oncotarget ◽

10.18632/oncotarget.11109 ◽

2016 ◽

Vol 7 (37) ◽

pp. 60169-60180 ◽

Cited By ~ 16

Author(s):

Junjie Piao ◽

Liyan Chen ◽

Taihao Quan ◽

Longshan Li ◽

Chunji Quan ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor Trichostatin

Mtor Inhibitor ◽

Trichostatin A ◽

Superior Efficacy ◽

Deacetylase Inhibitor ◽

The anti-tumor effects of dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A on inducing autophagy in esophageal squamous cell carcinoma

Journal of Cancer ◽

10.7150/jca.22861 ◽

2018 ◽

Vol 9 (6) ◽

pp. 987-997 ◽

Cited By ~ 9

Author(s):

Ning Wu ◽

Yingfeng Zhu ◽

Xiao Xu ◽

Yongjun Zhu ◽

Yang Song ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Histone Deacetylase ◽

Squamous Cell ◽

Histone Deacetylase Inhibitor Trichostatin

Mtor Inhibitor ◽

Trichostatin A ◽

Deacetylase Inhibitor ◽

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer

Oncotarget ◽

10.18632/oncotarget.724 ◽

2012 ◽

Vol 3 (11) ◽

pp. 1416-1427 ◽

Cited By ~ 34

Author(s):

Sreedhar Venkannagari ◽

Warren Fiskus ◽

Karissa Peth ◽

Peter Atadja ◽

Manuel Hidalgo ◽

...

Keyword(s):

Pancreatic Cancer ◽

Histone Deacetylase ◽

Mtor Inhibitor ◽

Human Pancreatic Cancer ◽

Superior Efficacy ◽

Phase I study of the mTOR inhibitor everolimus in combination with the histone deacetylase inhibitor panobinostat in patients with advanced clear cell renal cell carcinoma

Investigational New Drugs ◽

10.1007/s10637-019-00864-7 ◽

2019 ◽

Vol 38 (4) ◽

pp. 1108-1116 ◽

Cited By ~ 1

Author(s):

Anthony Wood ◽

Saby George ◽

Nabil Adra ◽

Sreenivasulu Chintala ◽

Nur Damayanti ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Phase I ◽

Histone Deacetylase ◽

Renal Cell ◽

Phase I Study ◽

Mtor Inhibitor ◽

Clear Cell ◽

Cell Renal Cell Carcinoma ◽

DIPG-61. HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT SYNERGIZES WITH DUAL MTOR INHIBITOR TAK228 TO POTENTIATE KILLING OF DIPG CELLS

Neuro-Oncology ◽

10.1093/neuonc/noy059.154 ◽

2018 ◽

Vol 20 (suppl_2) ◽

pp. i61-i61

Author(s):

Smit Shah ◽

Jeffrey Rubens ◽

Charles Eberhart ◽

Eric Raabe

Keyword(s):

Histone Deacetylase ◽

Mtor Inhibitor ◽

Heat shock protein 90 inhibition results in altered downstream signaling of mutant KIT and exerts synergistic effects on Kasumi-1 cells when combining with histone deacetylase inhibitor

Leukemia Research ◽

10.1016/j.leukres.2011.05.014 ◽

2011 ◽

Vol 35 (9) ◽

pp. 1212-1218 ◽

Cited By ~ 11

Author(s):

Wenjuan Yu ◽

Jianxiang Wang ◽

Jie Jin ◽

Wenbin Qian ◽

Jiejing Qian ◽

...

Keyword(s):

Heat Shock ◽

Heat Shock Protein ◽

Histone Deacetylase ◽

Synergistic Effects ◽

Heat Shock Protein 90 ◽

Downstream Signaling ◽

The mTOR inhibitor everolimus overcomes CXCR4-mediated resistance to histone deacetylase inhibitor panobinostat through inhibition of p21 and mitotic regulators

Biochemical Pharmacology ◽

10.1016/j.bcp.2019.07.016 ◽

2019 ◽

Vol 168 ◽

pp. 412-428

Author(s):

Katia Beider ◽

Hanna Bitner ◽

Valeria Voevoda-Dimenshtein ◽

Evgenia Rosenberg ◽

Yaarit Sirovsky ◽

...

Keyword(s):

Histone Deacetylase ◽

Mtor Inhibitor ◽

The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells

International Journal of Oncology ◽

10.3892/ijo.2015.2996 ◽

2015 ◽

Vol 47 (1) ◽

pp. 343-352 ◽

Cited By ~ 25

Author(s):

TOMAS GROH ◽

JAN HRABETA ◽

MOHAMMED ASHRAF KHALIL ◽

HELENA DOKTOROVA ◽

TOMAS ECKSCHLAGER ◽

...

Keyword(s):

High Risk ◽

Histone Deacetylase ◽

Synergistic Effects ◽

Neuroblastoma Cells ◽