scholarly journals Efficacy of lapatinib monotherapy on occult breast cancer presenting with cutaneous metastases: A case report

2014 ◽  
Vol 8 (6) ◽  
pp. 2448-2452 ◽  
Author(s):  
EIICHIRO NOGUCHI ◽  
TAKAKO KAMIO ◽  
HIDENORI KAMIO ◽  
HIROKO MIURA ◽  
MASAKO TAMAKI ◽  
...  
Author(s):  
Mehmet Zahid Kocak ◽  
Murat Araz ◽  
Mustafa Karaagac ◽  
Dilek Caglayan ◽  
Mustafa Korkmaz ◽  
...  

Author(s):  
Inês Morais Rodrigues ◽  
Fernando Igreja ◽  
Isabel Riscado ◽  
Rosa Madureira ◽  
Ana Nobre Pinto

The Breast ◽  
2011 ◽  
Vol 20 ◽  
pp. S36-S37
Author(s):  
Riccardo Bussone ◽  
Sara Bustreo ◽  
Ada Ala ◽  
Roberto Cianci ◽  
Simona Bevilacqua ◽  
...  

2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
David Guillermo Gómez Garnica ◽  
Catalina Barco-Castillo ◽  
Diego Vanegas ◽  
Mónica Sofía Benavides ◽  
María Helena Astorquiza

ABOUTOPEN ◽  
2017 ◽  
Vol 3 (1) ◽  
pp. 95-99
Author(s):  
Giovanni Ceccon ◽  
Stefano Andreani ◽  
Maria Luisa Bergamini ◽  
Cristina Dell’Anna ◽  
Francesca Ghetti ◽  
...  

Breast cancer is the most frequent tumour in women around the world and it accounts for 25% of all cases of cancer. It may spread through the body in various districts, and as a consequence pulmonary, bone, liver, cerebral, lymph node and skin metastases are commonly seen. Skin metastases can be both locoregional (near the tumor) and distant. The skin appearance should not be underestimated in multi-metastatic patients, as tumorous progression in the skin inevitably causes ulceration, extreme difficulty in cicatrization and consequent pain. In this study, we describe the case of a multiple treated patient for destructive cutaneous metastases (Oncology).


2002 ◽  
Vol 88 (6) ◽  
pp. 532-534 ◽  
Author(s):  
Fabrizio Maria Frattaroli ◽  
Alessandro Carrara ◽  
Anna Maria Conte ◽  
Giuseppe Pappalardo

Axillary lymph node metastasis from an occult breast carcinoma is a rare occurrence. We report this condition in a 59-year-old woman who presented with a swelling in the right axilla. No breast mass was clinically evident. Mammography, ultrasonography and multiple random fine-needle breast biopsies yielded no pathological findings. No extramammary primary lesions were present. Axillary sampling was performed and histological examination revealed the presence of metastatic adenocarcinoma in three of the 12 dissected lymph nodes. Estrogen receptors were positive and immunohistochemistry pointed to a breast origin. All these data were suggestive of occult breast cancer. The patient refused any further treatment but accepted clinical and radiological follow-up. Eight years later mammography revealed in the same breast a 10-mm nodule containing microcalcifications, which was not evident at physical examination. The patient underwent a lumpectomy. Intraoperative histology was positive for breast carcinoma and complete axillary clearance was performed. Histological examination revealed a lobular invasive breast carcinoma and the presence of micrometastasis in one of the 23 removed lymph nodes. The patient was given radiotherapy to the breast and axilla and tamoxifen. At present, one year after the appearance of the primary tumor, she is free of disease. Based on this case report we suggest an eclectic approach in the management of patients with axillary metastasis from occult breast cancer, depending on the clinical, pathological and biological findings.


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