scholarly journals The family of apoptosis-stimulating proteins of p53 is dysregulated in colorectal cancer patients

2018 ◽  
Author(s):  
Libin Yin ◽  
Yuyang Lin ◽  
Xu Wang ◽  
Yanzhuo Su ◽  
Han Hu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
The Family ◽  
Colorectal Cancer Patients

scholarly journals Family’s Experience: Nursing Care for Colorectal Cancer Patients with Colostomy

2020 ◽  
Vol 10 (1) ◽  
pp. 96-106
Author(s):  
Untung Sujianto ◽  
Roland Billy ◽  
Ani Margawati
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Nursing Care ◽  
Nursing Practice ◽  
Inclusion Criteria ◽  
Family Experience ◽  
Descriptive Phenomenology ◽  
The Family ◽  
Colorectal Cancer Patients ◽  
Depth Interviews

Background: Colorectal cancer patients with colostomy have various complaints about changes in their life including the need for comprehensive and personal care. Ostomy nurses are responsible for managing people with a colostomy, and this particular nursing practice continues to develop globally. Also, previous literature highlights the importance of caregiver’s support, particularly family in colostomy patient care.Purpose: This study aimed to explore the family experience of colorectal cancer patients toward colostomy nursing careMethods: The study design used was descriptive phenomenology to explore the experience of ten participants through in-depth interviews. The participants were selected using purposive sampling with the inclusion criteria: family members of colorectal cancer patients with colostomy, over 21 years old, and able to communicate verbally. The data were analyzed using Colaizzi's method.Results: The results revealed three themes related to the family’s experience: (1) positive and negative behavior in nursing care, (2) living with a colostomy, (3) expectations for nursing care. The findings showed that the families were happy with the ostomy nursing care though some aspects needed to be improved. However, colorectal cancer patients experienced some difficulties in living with a colostomy.Conclusion: The study concluded that the colostomy nursing care still needs to be improved. This study recommends the ostomy nurses to improve their nursing care, especially in terms of skills, responsiveness, and awareness.

Associations of daily partner responses with fatigue interference and relationship satisfaction in colorectal cancer patients.

2018 ◽  
Vol 37 (11) ◽  
pp. 1015-1024
Author(s):  
Fabiola Müller ◽  
Marrit A. Tuinman ◽  
Ellen Stephenson ◽  
Ans Smink ◽  
Anita DeLongis ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Relationship Satisfaction ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

Safety and Quality of Life in the Treatment of Non-metastasic Colorectal Cancer Patients: 5-fluorouracil Versus Capecitabine

2019 ◽  
Author(s):  
Julia Sánchez-Gundín ◽  
Cristina Martín-Sabroso ◽  
Ana M. Fernández-Carballido ◽  
D. Barreda-Hernández ◽  
Ana I. Torres-Suárez
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

Neutrophil/lymphocyte Ratio after Flow Citometry Periferic Blood Cell Detection - Predictive Marker of Anastomotic Fistula in Colorectal Cancer Surgery

2020 ◽  
Vol 71 (6) ◽  
pp. 295-306
Author(s):  
Dumitru Radulescu ◽  
Vlad Dumitru Baleanu ◽  
Andrei Nicolaescu ◽  
Marius Lazar ◽  
Marius Bica ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Rectal Surgery ◽  
Predictive Marker ◽  
Fistula Formation ◽  
Cell Detection ◽  
Colon And Rectal Surgery ◽  
Optimal Value ◽  
Anastomotic Fistula ◽  
Colorectal Cancer Patients

Anastomotic fistula is a dreadful complication of colon and rectal surgery that can put life into danger, being common after colorectal surgery. The preoperative lymphocyte neutrophil ratio (NLR) is known as a prognostic marker for colorectal cancer patients. The existence of a predictive marker of anastomotic fistula in colorectal cancer patients is not fully undestood, so we proposed to investigate the utility of preoperative NLR as a predictor of anastomotic fistula formation. This study the Neutrophils and lymphocytes were detected from periferic blood using flow citometry. We retrospectively evaluated 161 patients with colorectal cancer, who were treated curatively, in which at least one anastomosis was performed, comparing NLR values between patients who had fistula and those with normal healing, then comparing the group with low NLR, with the group with increased NLR, after finding the optimal value of NLR using the ROC curve.The optimal value of the NLR after establishing the cutoff value was 3.07. Between the low NLR group (n=134) and the high NLR group (n=27), were observed statistically significant differences in fistula (p [0.001) and death (p=0.001). The odds ratio for failure in the group with increased NLR was 10.37, which means that patients with NLR]3.54 have a chance of developing anastomotic fistula greater than 10.37 comparable to patients with lower NLR. We suggest the preoperative use of NLR can be used as a predictive marker of anastomotic fistula than can increase the quality of preoperative preparation and therefore the establishment of the optimal surgical technique that can lead to anastomotic fistula risk decrease.

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