Clinical diagnostic value of digestive endoscopic narrow-band imaging in early esophageal cancer

ABSTRACT BACKGROUND The diagnosis of corrosion cancer should be suspected in patients with corrosive ingestion if after a latent period of negligible symptoms there is development of dysphagia, or poor response to dilatation, or if respiratory symptoms develop in an otherwise stable patient of esophageal stenosis. Narrow Band Imaging detects superficial squamous cell carcinoma more frequently than white-light imaging, and has significantly higher sensitivity and accuracy compared with white-light. OBJECTIVE To determinate the clinical applicability of Narrow Band Imaging versus Lugol´s solution chromendoscopy for detection of early esophageal cancer in patients with caustic/corrosive agent stenosis. METHODS Thirty-eight patients, aged between 28-84 were enrolled and examined by both Narrow Band Imaging and Lugol´s solution chromendoscopy. A 4.9mm diameter endoscope was used facilitating examination of a stenotic area without dilation. Narrow Band Imaging was performed and any lesion detected was marked for later biopsy. Then, Lugol´s solution chromoendoscopy was performed and biopsies were taken at suspicious areas. Patients who had abnormal findings at the routine, Narrow Band Imaging or Lugol´s solution chromoscopy exam had their stenotic ring biopsied. RESULTS We detected nine suspicious lesions with Narrow Band Imaging and 14 with Lugol´s solution chromendoscopy. The sensitivity and specificity of the Narrow Band Imaging was 100% and 80.6%, and with Lugol´s chromoscopy 100% and 66.67%, respectively. Five (13%) suspicious lesions were detected both with Narrow Band Imaging and Lugol’s chromoscopy, two (40%) of these lesions were confirmed carcinoma on histopathological examination. CONCLUSION Narrow Band Imaging is an applicable option to detect and evaluate cancer in patients with caustic /corrosive stenosis compared to the Lugol´s solution chromoscopy.

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Narrow-band imaging with magnifying endoscopy for the screening of esophageal cancer in patients with primary head and neck cancers

Endoscopy ◽

10.1055/s-0030-1255514 ◽

2010 ◽

Vol 42 (08) ◽

pp. 613-619 ◽

Cited By ~ 69

Author(s):

C. Lee ◽

C. Chang ◽

Y. Lee ◽

C. Tai ◽

W. Wang ◽

...

Keyword(s):

Esophageal Cancer ◽

Head And Neck ◽

Narrow Band ◽

Narrow Band Imaging ◽

Magnifying Endoscopy ◽

Head And Neck Cancers

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AB066. The diagnostic value of narrow-band imaging for flat bladder lesions

Translational Andrology and Urology ◽

10.21037/tau.2018.ab066 ◽

2018 ◽

Vol 7 (S5) ◽

pp. AB066-AB066

Author(s):

Yifan Chang ◽

Yinghao Sun ◽

Zhensheng Zhang ◽

Weidong Xu ◽

Meimian Hua ◽

...

Keyword(s):

Narrow Band ◽

Narrow Band Imaging ◽

Diagnostic Value

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A new exploration of white globe appearance (WGA) in ulcerative lesions

Zeitschrift für Gastroenterologie ◽

10.1055/a-1200-2287 ◽

2020 ◽

Vol 58 (08) ◽

pp. 754-760

Author(s):

Jinnian Cheng ◽

Jie Xia ◽

Qian Zhuang ◽

Xianjun Xu ◽

Xiaowan Wu ◽

...

Keyword(s):

Narrow Band ◽

Narrow Band Imaging ◽

Diagnostic Value ◽

Imaging Data ◽

Clinical Value ◽

Significant Difference ◽

Cancerous Lesions ◽

Ulcerative Lesions ◽

Reliable Marker ◽

Tree Branch

Abstract Aim White globe appearance (WGA), a small white lesion with a globular shape that can be clearly visualized by magnifying endoscopy with narrow-band imaging (ME-NBI), was reported to be a reliable marker of early gastric cancer (EGC). However, we found that this endoscopic presentation could also be seen in non-cancerous tissues, especially in ulcerative lesions. This study aimed to further investigate the diagnostic value of WGA in differentiating non-cancerous lesions from EGC in ulcer-type cases. Materials and Methods We retrospectively reviewed 54 cases of EGC and 155 cases of non-cancerous lesions in this study, all of which had endoscopic imaging data of ME-NBI scanning and pathological data of biopsy or resected specimens. The correlation of the prevalence of WGA and ulcerative lesions, as well as the characteristics of WGA between the 2 groups were analyzed in this study. Results WGA was more common in ulcerative lesions (27.6 %, 21/76) than in non-ulcerative lesions (3.8 %, 5/133) (p < 0.001) in our study. In the ulcerative cases, no significant difference in prevalence of WGA was observed between EGC and non-cancerous lesions (p = 0.532). Compared with WGA in EGC, WGA in non-cancerous lesions tended to show the characteristic of tree-branch-like vessels on globular shape (p < 0.001). Conclusions WGA is more likely to occur in ulcerative lesions, and the presence of WGA alone cannot distinguish EGC from non-cancerous lesions in ulcer-type cases. In WGA-positive tissue, tree-branch-like vessels of globular shape may provide a certain clinical value in diagnosis of non-cancerous lesions or EGC.

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Additional effect of magnifying narrow‐band imaging on estimating the invasion depth of superficial esophageal cancer

JGH Open ◽

10.1002/jgh3.12246 ◽

2020 ◽

Vol 4 (2) ◽

pp. 178-184 ◽

Cited By ~ 1

Author(s):

Minoru Kato ◽

Yoshito Hayashi ◽

Ryotaro Uema ◽

Keiichi Kimura ◽

Takanori Inoue ◽

...

Keyword(s):

Esophageal Cancer ◽

Narrow Band ◽

Narrow Band Imaging ◽

Invasion Depth ◽

Superficial Esophageal Cancer

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548 NARROW BAND IMAGING ENDOSCOPY VERSUS LUGOL CHROMOENDOSCOPY IN SCREENING FOR ESOPHAGEAL CANCER AMONG PATIENTS WITH HEAD AND NECK CANCERS: A RANDOMIZED TRIAL

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2019.04.085 ◽

2019 ◽

Vol 89 (6) ◽

pp. AB93-AB94

Author(s):

Anna Chaber-Ciopinska ◽

Michal F. Kaminski ◽

Paulina Wieszczy ◽

Andrzej Bielasik ◽

Marek Bugajski ◽

...

Keyword(s):

Esophageal Cancer ◽

Randomized Trial ◽

Head And Neck ◽

Narrow Band ◽

Narrow Band Imaging ◽

Head And Neck Cancers

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Clinical experience of narrow band imaging (NBI) usage in diagnosis of laryngeal lesions

Otolaryngologia Polska ◽

10.5604/01.3001.0013.3401 ◽

2019 ◽

Vol 73 (6) ◽

pp. 18-23 ◽

Cited By ~ 1

Author(s):

Barbara Popek ◽

Katarzyna Bojanowska-Poźniak ◽

Bartłomiej Tomasik ◽

Wojciech Fendler ◽

Joanna Jeruzal-Świątecka ◽

...

Keyword(s):

White Light ◽

Narrow Band ◽

Histopathological Examination ◽

Narrow Band Imaging ◽

Daily Practice ◽

Diagnostic Value ◽

Severe Dysplasia ◽

White Light Endoscopy ◽

Laryngeal Lesions ◽

Sensitivity Specificity

Introduction: One of the most recent methods used in imaging of the larynx is narrow band imaging (NBI). NBI enables us to detect specific patterns of pathological angiogenesis suggestive of premalignant or neoplastic lesions. The aim of the study was to compare imaging of laryngeal lesions in white light endoscopy (WLE) and NBI in relation to histopathological examination. Material and methods: 333 patients with laryngeal lesions underwent endoscopic evaluation in WLE and NBI. Sensitivity, specificity, positive and negative predictive value (PPV, NPV) for WLE and NBI were calculated. The diagnostic value for WLE and NBI was evaluated for two assumptions (positive result is:1. severe dysplasia and cancer 2. only cancer) Results: Sensitivity, specificity, PPV, NPV of first assumption were respectively for white light compared to NBI: 95.4% vs 98.5%; 84.2% vs 98.5%; 79.6% vs 97.7% and 96.6% vs 99.0%. The values of second assumption were: 97.4% vs 100%; 79.3% vs 93.5%; 72.6% vs. 89.4% and 98.2% vs. 100.0%. Higher sensitivity was observed for the second assumption, while higher specifity was recorded for the first assumption. Specificity was significantly higher for NBI than for WLE (p<0.001). Conclusions: NBI enables us to detect and differentiate laryngeal lesions, which are invisible in WLE. Endoscopic examination, especially in NBI-mode, is non-invasive, repeatable and remains a useful tool in the daily practice and diagnosis of patients with pathological lesions in the larynx.

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