A new exploration of white globe appearance (WGA) in ulcerative lesions

2020 ◽  
Vol 58 (08) ◽  
pp. 754-760
Author(s):  
Jinnian Cheng ◽  
Jie Xia ◽  
Qian Zhuang ◽  
Xianjun Xu ◽  
Xiaowan Wu ◽  
...  
Keyword(s):  
Narrow Band ◽  
Narrow Band Imaging ◽  
Diagnostic Value ◽  
Imaging Data ◽  
Clinical Value ◽  
Significant Difference ◽  
Cancerous Lesions ◽  
Ulcerative Lesions ◽  
Reliable Marker ◽  
Tree Branch

Abstract Aim White globe appearance (WGA), a small white lesion with a globular shape that can be clearly visualized by magnifying endoscopy with narrow-band imaging (ME-NBI), was reported to be a reliable marker of early gastric cancer (EGC). However, we found that this endoscopic presentation could also be seen in non-cancerous tissues, especially in ulcerative lesions. This study aimed to further investigate the diagnostic value of WGA in differentiating non-cancerous lesions from EGC in ulcer-type cases. Materials and Methods We retrospectively reviewed 54 cases of EGC and 155 cases of non-cancerous lesions in this study, all of which had endoscopic imaging data of ME-NBI scanning and pathological data of biopsy or resected specimens. The correlation of the prevalence of WGA and ulcerative lesions, as well as the characteristics of WGA between the 2 groups were analyzed in this study. Results WGA was more common in ulcerative lesions (27.6 %, 21/76) than in non-ulcerative lesions (3.8 %, 5/133) (p < 0.001) in our study. In the ulcerative cases, no significant difference in prevalence of WGA was observed between EGC and non-cancerous lesions (p = 0.532). Compared with WGA in EGC, WGA in non-cancerous lesions tended to show the characteristic of tree-branch-like vessels on globular shape (p < 0.001). Conclusions WGA is more likely to occur in ulcerative lesions, and the presence of WGA alone cannot distinguish EGC from non-cancerous lesions in ulcer-type cases. In WGA-positive tissue, tree-branch-like vessels of globular shape may provide a certain clinical value in diagnosis of non-cancerous lesions or EGC.

scholarly journals AB066. The diagnostic value of narrow-band imaging for flat bladder lesions

2018 ◽  
Vol 7 (S5) ◽  
pp. AB066-AB066
Author(s):  
Yifan Chang ◽  
Yinghao Sun ◽  
Zhensheng Zhang ◽  
Weidong Xu ◽  
Meimian Hua ◽  
...  
Keyword(s):  
Narrow Band ◽  
Narrow Band Imaging ◽  
Diagnostic Value

Clinical experience of narrow band imaging (NBI) usage in diagnosis of laryngeal lesions

2019 ◽  
Vol 73 (6) ◽  
pp. 18-23 ◽  
Author(s):  
Barbara Popek ◽  
Katarzyna Bojanowska-Poźniak ◽  
Bartłomiej Tomasik ◽  
Wojciech Fendler ◽  
Joanna Jeruzal-Świątecka ◽  
...  
Keyword(s):  
White Light ◽  
Narrow Band ◽  
Histopathological Examination ◽  
Narrow Band Imaging ◽  
Daily Practice ◽  
Diagnostic Value ◽  
Severe Dysplasia ◽  
White Light Endoscopy ◽  
Laryngeal Lesions ◽  
Sensitivity Specificity

Introduction: One of the most recent methods used in imaging of the larynx is narrow band imaging (NBI). NBI enables us to detect specific patterns of pathological angiogenesis suggestive of premalignant or neoplastic lesions. The aim of the study was to compare imaging of laryngeal lesions in white light endoscopy (WLE) and NBI in relation to histopathological examination. Material and methods: 333 patients with laryngeal lesions underwent endoscopic evaluation in WLE and NBI. Sensitivity, specificity, positive and negative predictive value (PPV, NPV) for WLE and NBI were calculated. The diagnostic value for WLE and NBI was evaluated for two assumptions (positive result is:1. severe dysplasia and cancer 2. only cancer) Results: Sensitivity, specificity, PPV, NPV of first assumption were respectively for white light compared to NBI: 95.4% vs 98.5%; 84.2% vs 98.5%; 79.6% vs 97.7% and 96.6% vs 99.0%. The values of second assumption were: 97.4% vs 100%; 79.3% vs 93.5%; 72.6% vs. 89.4% and 98.2% vs. 100.0%. Higher sensitivity was observed for the second assumption, while higher specifity was recorded for the first assumption. Specificity was significantly higher for NBI than for WLE (p<0.001). Conclusions: NBI enables us to detect and differentiate laryngeal lesions, which are invisible in WLE. Endoscopic examination, especially in NBI-mode, is non-invasive, repeatable and remains a useful tool in the daily practice and diagnosis of patients with pathological lesions in the larynx.

The Diagnostic Value of Narrow-Band Imaging for the Detection of Nasopharyngeal Carcinoma

ORL ◽  
2012 ◽  
Vol 74 (5) ◽  
pp. 235-239 ◽  
Author(s):  
Haidi Yang ◽  
Yiqing Zheng ◽  
Qiujian Chen ◽  
Hao Xiong ◽  
Bin Chen ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Diagnostic Value

scholarly journals Diagnostic Value and Pathological Correlation of Narrow Band Imaging Classification in Laryngeal Lesions

2020 ◽  
pp. 014556132092532 ◽  
Author(s):  
Chuanyao Lin ◽  
Sisi Zhang ◽  
Ling Lu ◽  
Maohua Wang ◽  
Xiaoyun Qian
Keyword(s):  
Predictive Value ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Diagnostic Value ◽  
Pathological Correlation ◽  
Laryngeal Lesions ◽  
Loop Pattern ◽  
Malignant Lesions ◽  
High Consistency ◽  
Sensitivity Specificity

Objectives: To explore the diagnostic value and pathological correlation of narrow band imaging (NBI) classification in laryngeal lesions. Methods: A total of 112 patients (123 lesions) with laryngeal lesions from July 2018 to May 2019 were selected in this study. All patients were examined by NBI and white light imaging endoscopy. The NBI endoscopy was applied to classify the observed lesion sites according to intraepithelial papillary capillary loop pattern. The gold standard of diagnosis was pathological results. To evaluate the consistency of NBI classification and pathological results. Results: The sensitivity, specificity, positive predictive value, and negative predictive value of the diagnosis for benign, precancerous, and malignant lesions under the NBI endoscopy were 90.91%, 81.19%, 74.07%, 85.42%; 41.67%, 92.93%, 58.82%, 86.79%; and 93.51%, 65.22%, 91.14%, 68.18%, respectively. There was a high consistency between NBI classification and pathological results (κ = 0.679, P < .001). Conclusions: The NBI classification can improve the accuracy of the diagnosis of laryngeal lesions. It is important for early diagnosis and treatment of vocal cord leukoplakia and laryngeal cancer.

scholarly journals A meta-analysis of narrow-band imaging for the diagnosis of primary nasopharyngeal carcinoma

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 759 ◽  
Author(s):  
David CM Yeung ◽  
Alexander C Vlantis ◽  
Eddy WY Wong ◽  
Michael CF Tong ◽  
Jason YK Chan
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Likelihood Ratio ◽  
White Light ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Positive Likelihood Ratio ◽  
Negative Likelihood Ratio ◽  
Detection Rates ◽  
White Light Endoscopy ◽  
Significant Difference

Background: Narrow band imaging (NBI), an endoscopic technique featuring an augmented definition of microvasculature and mucosal patterns. NBI is increasingly advocated as a tool to characterize neoplasia and intestinal metaplasia in endoscopic standards, such as for colorectal polyps and tumors. Recently NBI has also been studied in the detection of Nasopharyngeal Carcinoma (NPC). Here we aimed to assess the diagnostic utility of NBI for the diagnosis of NPC. Methods: A meta-analysis of studies comparing narrow-band imaging and white light endoscopy in the diagnosis of primary nasopharyngeal carcinoma was performed. The review process involved two independent investigators. The databases used were MEDLINE, PubMed, the Cochrane library, Embase, and the Web of Science. Statistical analysis was performed with OpenMetaAnalyst, MetaDiSc version 1.4, and Medcalc version 17.9.7.  Results: Five studies including 2480 patients were included. The sensitivity and specificity for narrow-band imaging were 0.90 (0.73-0.97) and 0.95 (0.81-0.99) respectively. The positive likelihood ratio and negative likelihood ratio were 18.82 (0.31-82.1) and 0.08 (0.02-0.31). For white light endoscopy, the sensitivity and specificity were 0.77 (0.58-0.89) and 0.91 (0.79-0.96). The positive likelihood ratio was 7.61 (3.61-16.04), and the negative likelihood ratio was 0.21 (0.11-0.39). The odds ratio for detection rates between narrow-band imaging and white light endoscopy was 4.29 (0.56-33.03, p = 0.16). Area under the curve for narrow-band imaging was 0.98 (SE: 0.02), and for white light it was 0.93 (SE: 0.03). There was no significant difference in the receiver operating characteristic curves between the two modalities (p = 0.14). Conclusion: Narrow-band imaging showed a higher sensitivity and positive likelihood ratio for the diagnosis of nasopharyngeal carcinoma. However, there was no significant difference in detection rates compared to white light endoscopy. Further investigation with a uniform diagnostic criteria and terminology is needed for narrow-band imaging in the diagnosis of nasopharyngeal carcinoma.

The diagnostic value of endoscopic narrow band imaging in helicobacter pylori gastritis in children

2015 ◽  
Vol 26 (2) ◽  
pp. 112-116 ◽  
Author(s):  
Taner Ozgur ◽  
Tanju Basarir Ozkan ◽  
Gulin Erdemir ◽  
Cuneyt Ozakin ◽  
Omer Yerci
Keyword(s):  
Helicobacter Pylori ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Diagnostic Value ◽  
Helicobacter Pylori Gastritis

The diagnostic value of perpendicular vascular patterns of vocal cords defined by narrow-band imaging

2020 ◽  
Vol 277 (6) ◽  
pp. 1715-1723 ◽  
Author(s):  
Robert Šifrer ◽  
Maja Šereg-Bahar ◽  
Nina Gale ◽  
Irena Hočevar-Boltežar
Keyword(s):  
Narrow Band ◽  
Narrow Band Imaging ◽  
Diagnostic Value ◽  
Vocal Cords

scholarly journals Narrow-Band Imaging Magnifying Endoscopy versus Lugol Chromoendoscopy with Pink-Color Sign Assessment in the Diagnosis of Superficial Esophageal Squamous Neoplasms: A Randomised Noninferiority Trial

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Kenichi Goda ◽  
Akira Dobashi ◽  
Noboru Yoshimura ◽  
Masayuki Kato ◽  
Hiroyuki Aihara ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Diagnostic Accuracy ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Magnifying Endoscopy ◽  
Noninferiority Trial ◽  
Pink Color ◽  
Significant Difference

Previous studies have shown the high diagnostic accuracy of narrow-band imaging magnifying endoscopy (NBI-ME) and Lugol chromoendoscopy with pink-color sign assessment (LCE-PS) for superficial esophageal squamous cell carcinoma (SESCC). However, there has been no controlled trial comparing these two diagnostic techniques. We conducted a randomized noninferiority trial to compare the diagnostic accuracy of NBI-ME and LCE-PS. We recruited patients with, or with a history of, squamous cell carcinoma in the head and neck region or in the esophagus. They were randomly assigned to either NBI-ME or LCE-PS. When lesions > 5 mm in diameter were found as brownish areas on NBI or as Lugol-voiding lesions (LVL), they were evaluated to determine whether they are SESCC on the basis of the findings of NBI-ME or PS in the LVL. NBI-ME and LCE-PS were completed in 147 patients each. There was no significant difference in all diagnostic values between the two techniques. Compared with LCE-PS, NBI-ME showed a significantly shorter examination time but a larger number of misdiagnosed lesions especially in patients with many irregularly shaped multiform LVLs. Compared with LCE-PS, NBI-ME might be similarly accurate and less invasive, but less reliable in patients with many LVLs, in the diagnosis of SESCC.

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