scholarly journals Predictive factors for restoration of heart beat in cardiopulmomonary arrest cases-Blood gas parameters, potassium and lactate in the central venous blood.

1996 ◽  
Vol 7 (6) ◽  
pp. 281-291
Author(s):  
Tomomi Ohishi
2019 ◽  
Author(s):  
Shaopeng Gang ◽  
Ling Jiang ◽  
Kaiyun Fang ◽  
Xiulun Liu ◽  
Daokang Xiang ◽  
...  

Abstract Background: The associations of the different blood gas parameters from different blood samples harvested at different stages during adult cardiac surgery with the postoperative outcomes are inadequately studied. Methods: Adult patients undergoing elective cardiac surgery with cardiopulmonary bypass (CPB) participated in this prospective observational study. Blood gas parameters from arterial, central venous, and jugular bulb venous blood samples harvested simultaneously at pre-determined time points (baseline with the patient awake, post-anesthesia induction but before CPB, during CPB at 30°C, during CPB at 37°C (rewarming), and at the end of surgery) were correlated with postoperative outcomes including the length of mechanical ventilation (LMV), intensive care unit stay (LICU), hospital stay (LOH), and major organ morbidity and mortality. Results: Data from 193 patients were analyzed. Multiple parameters of different blood harvested at different stages significantly correlated with one or more outcome measures based on univariate analysis (p < 0.05). However, only the jugular bulb venous blood pH and carbon dioxide tension and the central venous blood pH at the end of surgery (pHcv-end) were significantly correlated with LMV, LICU, and LOH (p < 0.05). A more alkaline blood correlated with more favorable outcomes. After adjusting for age, surgical time, and total intravenous volume administered, multivariate analysis showed that only pHcv-end remained independently associated with LMV and LICU (p < 0.05). Conclusion: More alkaline blood, especially the central venous blood at the end of surgery, is associated with more favorable outcomes after adult cardiac surgery. Trial registration ChiCTR-POC-17013942, Date of registration December 15, 2017.


2019 ◽  
Author(s):  
Shaopeng Gang ◽  
Ling Jiang ◽  
Kaiyun Fang ◽  
Xiulun Liu ◽  
Daokang Xiang ◽  
...  

Abstract Background: The associations of the different blood gas parameters from different blood samples harvested at different stages during adult cardiac surgery with the postoperative outcomes are inadequately studied. Methods: Adult patients undergoing elective cardiac surgery with cardiopulmonary bypass (CPB) participated in this prospective observational study. Blood gas parameters from arterial, central venous, and jugular venous blood samples harvested simultaneously at pre-determined time points (baseline with the patient awake, post-anesthesia induction but before CPB, during CPB at 30°C, during CPB at 37°C (rewarming), and at the end of surgery) were correlated with postoperative outcomes including the length of mechanical ventilation (LMV), intensive care unit stay (LICU), hospital stay (LOH), and major organ morbidity and mortality. Results: Data from 193 patients were analyzed. Multiple parameters of different blood harvested at different stages significantly correlated with one or more outcome measures based on univariate analysis (p < 0.05). However, only the jugular venous blood pH and carbon dioxide tension and the central venous blood pH at the end of surgery (pHcv-end) were significantly correlated with LMV, LICU, and LOH (p < 0.05). A more alkaline blood correlated with more favorable outcomes. After adjusting for age, surgical time, and total intravenous volume administered, multivariate analysis showed that only pHcv-end remained independently associated with LMV and LICU (p < 0.05). Conclusion: More alkaline blood, especially the central venous blood at the end of surgery, is associated with more favorable outcomes after adult cardiac surgery. Trial registration ChiCTR-POC-17013942, Date of registration December 15, 2017.


2009 ◽  
Vol 25 (2) ◽  
pp. 104-110 ◽  
Author(s):  
Allan J. Walkey ◽  
Harrison W. Farber ◽  
Charles O'Donnell ◽  
Howard Cabral ◽  
Janet S. Eagan ◽  
...  

2015 ◽  
Vol 77 (7) ◽  
pp. 865-869 ◽  
Author(s):  
Jun TAMURA ◽  
Takaharu ITAMI ◽  
Tomohito ISHIZUKA ◽  
Sho FUKUI ◽  
Kenjirou MIYOSHI ◽  
...  

Nephron ◽  
2018 ◽  
Vol 139 (4) ◽  
pp. 293-298 ◽  
Author(s):  
Sarah J. Schrauben ◽  
Dan Negoianu ◽  
Cristiana Costa ◽  
Raphael M. Cohen ◽  
Stanley Goldfarb ◽  
...  

2010 ◽  
Vol 27 (10) ◽  
pp. 890-896 ◽  
Author(s):  
Oliver M Theusinger ◽  
Caroline Thyes ◽  
Philippe Frascarolo ◽  
Sebastian Schramm ◽  
Burkhardt Seifert ◽  
...  

2020 ◽  
Vol 17 (3) ◽  
pp. 6-16
Author(s):  
A. B. Naumov ◽  
Yu. S. Polushin ◽  
G. G. Khubulava ◽  
Yu. S. Аleksandrovich ◽  
S. P. Marchenko ◽  
...  

The objective: to identify laboratory markers of systemic perfusion in newborns with functional single ventricle on mechanical ventilation after surgical correction. Subjects and methods. Blood gas parameters were retrospectively analyzed in 52 newborns with congenital heart defects with univentricular hemodynamic after surgical correction. All samples were divided into three groups based on arterial blood saturation (SaO2): Group 1 – hypoxia (SaO2 ≤ 65%); Group 2 – normoxemia (SaO2 = 65-85%); Group 3 – hyperoxemia (SaO2 > 85%). Stroke volume and cardiac index were evaluated with echocardiography. The oxygen consumption and carbon metabolism were evaluated by arterial and venous blood gases. Results. The mixed central venous pO2 (PvO2) > 29.5 mm Hg, mixed central venous O2 (SvO2) > 54.5%, arteriovenous difference in saturation (Sa-vO2) < 15.8%, total oxygen content in venous blood (CvO2) > 119 ml/l, oxygen extraction ratio (O2ER) < 19% and the arteriovenous difference in partial pressure of carbon dioxide (dPCO2) < 5.4 mm Hg are cut off criteria for adequate systemic perfusion. PvO2 < 26 mm Hg, SvO2 < 44.5%, Sa-vO 2 > 27%, CvO2 < 88 ml/l, O2ER > 27.7%, dPCO2> 7.9 mm Hg have been associated with decreased systemic perfusion. The logistic regression model including combination of O2ER and dPCO2 predicts adequate systemic flow accuracy of 94.3% (sensitivity 87.5%, specificity 94.7%, p = 0.001). Graphics allow to adapt the mathematical model to clinical practice to verify systemic hypoperfusion in newborns with functional single ventricle. Conclusion: The following cut off parameters allow to assess systemic perfusion in newborns with functional single ventricle: PvO2, SvO2, CvO2, Sa-vO 2, O2ER, and dPCO2. The model for predicting the adequacy of systemic perfusion can be used as an effective tool to monitor hemodynamic status in newborns with functional single ventricle.


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