scholarly journals Prevalence and Clinical Significance of Anti-DFS70 in Antinuclear Antibody (ANA)–positive Patients Undergoing Routine ANA Testing in a New Zealand Public Hospital

2018 ◽  
Vol 45 (2) ◽  
pp. 289-291 ◽  
Author(s):  
STACEY LUCAS ◽  
WEE LEONG CHANG ◽  
FABRICE MERIEN
2015 ◽  
Vol 43 ◽  
pp. 118-127 ◽  
Author(s):  
Paul Brown ◽  
Laura Panattoni ◽  
Linda Cameron ◽  
Stephanie Knox ◽  
Toni Ashton ◽  
...  

1971 ◽  
Vol 134 (3) ◽  
pp. 65-71 ◽  
Author(s):  
Frank J. Dixon ◽  
Michael B. A. Oldstone ◽  
Giorgio Tonietti

Observations based on elution of IgG from nephritic kidneys of NZ mice and absorption of the eluted IgG with selected antigens indicate that their immune complex nephritis involves at least two kinds of antigen-antibody complexes. Antibodies reactive with nuclear antigens account for nearly half of the IgG eluted from the kidneys while antibodies reactive with Gross viral antigens make up a significant but lesser amount. Superimposed chronic viral infections affect the nephritis of NZ mice in different ways. LCM and polyoma infections hasten and intensify the antinuclear antibody responses and glomerulonephritis of these mice while LDV infection appears to protect against both antinuclear antibody formation and development of nephritis.


1980 ◽  
Vol 25 (4) ◽  
pp. 293-298 ◽  
Author(s):  
A. E. El-Ghobarey ◽  
D. J. P. Sloane ◽  
K. Whaley

During the two-year period (1st October 1974–30th September 1976), 2979 sera were tested for DNA antibodies by the Farr test. One thousand six hundred and ninety-five of these were tested because they had high ANA titres (1/256 or greater). In this group 285 sera were found to have raised DNA binding capacities (DNA-bc), 86 of which were found in patients having diagnoses other than SLE. When the diagnoses were reviewed following the finding of a raised DNA-bc, 55 of these patients were found to be suffering from SLE. Of the 1284 sera tested for DNA antibodies without the prior ANA screening procedures, 288 were positive, 36 of which came from patients not considered to have SLE; 30 of these patients were subsequently shown to have SLE. Thus the DNA-bc test is an important tool in the diagnos is of SLE, and the ANA test appears to be a valuable screening procedure. The level of DNA-bc was not of any diagnostic value.


2013 ◽  
Vol 12 (10) ◽  
pp. 998-1003 ◽  
Author(s):  
Pieter Vermeersch ◽  
Xavier Bossuyt

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