The Pattern of Musculoskeletal Complaints in Patients with Suspected Psoriatic Arthritis and Their Correlation with Physical Examination and Ultrasound

2020 ◽  
pp. jrheum.190857
Author(s):  
Samantha Sarabia ◽  
Chandra Farrer ◽  
Jensen Yeung ◽  
Dana Jerome ◽  
Ker-Ai Lee ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Chronic Illness ◽  
Physical Examination ◽  
Functional Assessment ◽  
Patient Reported Outcomes ◽  
Advanced Practice ◽  
Musculoskeletal Complaints ◽  
Chronic Illness Therapy ◽  
Patient Reported

Objective To describe the pattern of musculoskeletal (MSK) symptoms and their correlation with clinical and sonographic findings among psoriasis patients with suspected psoriatic arthritis (PsA). Methods Patients with psoriasis and no prior diagnosis of PsA were referred for assessment of their MSK complaints. The study included the following steps: (1) assessment by an advanced practice physiotherapist, (2) targeted MSK ultrasound, and (3) assessment by a rheumatologist. In addition, patients were asked to complete questionnaires about the nature and duration of their MSK symptoms and to mark the location of their painful joints on a homunculus. Each patient was classified by a rheumatologist as “Not PsA,” “Possible PsA,” or “PsA”. MSK symptoms and patient-reported outcomes (PRO) were compared between patients with PsA and Possible/Not PsA. Agreement between modalities was assessed using κ statistics. Results Two hundred three patients with psoriasis and MK symptoms were enrolled (8.8% PsA, 23.6% Possible PsA). Patients classified as PsA had worse scores on the PsA Impact of Disease (P = 0.004) and Functional Assessment of Chronic Illness Therapy–Fatigue scale (P = 0.02). There was no difference between the 2 groups in the presence, distribution, and duration of MSK symptoms. Analysis of agreement in physical examination between modalities revealed the strongest agreement between the rheumatologist and physiotherapist (κ = 0.28). The lowest levels of agreement were found between ultrasound and patient (κ = 0.08) and physiotherapist and ultrasound (κ = 0.08). Conclusion The results of this study suggest that the intensity, rather than the type, duration, or distribution of MSK symptoms, is associated with PsA among patients with psoriasis.

scholarly journals Tradução e adaptação cultural para a língua portuguesa dos domínios Distúrbios do Sono e Distúrbios da Vigília do Patient-Reported-Outcomes Measurement Information System (PROMIS)

2014 ◽  
Vol 30 (7) ◽  
pp. 1391-1401 ◽  
Author(s):  
Zilma Maria Severino Silva e Costa ◽  
Rogério de Melo Costa Pinto ◽  
Tânia Maria da Silva Mendonça ◽  
Carlos Henrique Martins da Silva
Keyword(s):  
Information System ◽  
Chronic Illness ◽  
Functional Assessment ◽  
Patient Reported Outcomes ◽  
Measurement Information ◽  
Outcomes Measurement ◽  
Chronic Illness Therapy ◽  
Patient Reported ◽  
Measurement Information System

Alterações no sono e na vigília repercutem negativamente no estado de humor, na memória e no desempenho psicomotor do indivíduo, refletindo diretamente em sua qualidade de vida. Instrumentos de avaliação da qualidade desses fatores devem estar disponíveis para a avaliação clínica. O objetivo deste trabalho foi traduzir e adaptar culturalmente os domínios Distúrbios do Sono e Distúrbios da Vigília do instrumento de medida Patient-Reported Outcomes Measurement Information System (PROMIS) para a língua portuguesa. O processo de tradução e adaptação transcultural seguiu as orientações da organização Functional Assessment of Chronic Illness Therapy (FACIT). Essa metodologia compreende: tradução, reconciliação, retrotradução, revisão dos autores e dos revisores independentes, pré- teste e obtenção da versão final em português. A versão para a língua portuguesa dos domínios Distúrbios do Sono e Distúrbios da Vigília do PROMIS apresentou boa equivalência semântica, idiomática, cultural e conceitual dos itens.

scholarly journals Adaptação transcultural e validação da escala de Saúde Global do PROMIS para a língua portuguesa

2017 ◽  
Vol 33 (1) ◽  
Author(s):  
Camila Eugênia Zumpano ◽  
◽  
Tânia Maria da Silva Mendonça ◽  
Carlos Henrique Martins da Silva ◽  
Helena Correia ◽  
...  
Keyword(s):  
Information System ◽  
Chronic Illness ◽  
Functional Assessment ◽  
Patient Reported Outcomes ◽  
Measurement Information ◽  
Outcomes Measurement ◽  
Chronic Illness Therapy ◽  
Patient Reported ◽  
Measurement Information System

Resumo: O objetivo deste estudo foi realizar a adaptação transcultural da escala de Saúde Global do Patient-Reported Outcomes Measurement Information System (PROMIS) para a língua portuguesa. Os dez itens sobre Saúde Global foram adaptados transculturalmente por meio do método proposto pelo Functional Assessment of Chronic Illness Therapy (FACIT). A versão final do instrumento para a língua portuguesa foi autoadministrada em 1.010 participantes no Brasil. A precisão da escala foi verificada usando-se a análise dos efeitos piso e teto, confiabilidade da consistência interna e confiabilidade teste-reteste. Utilizou-se a análise fatorial exploratória e confirmatória para avaliação da validade de construto e dimensionalidade do instrumento. A calibração dos itens foi realizada por meio do Modelo de Resposta Gradual proposto por Samejima. Quatro itens globais necessitaram de ajustes após a realização do pré-teste. A análise das propriedades psicométricas demonstrou que a escala de Saúde Global tem boa confiabilidade, com coeficiente alfa de Cronbach de 0,83 e coeficiente de correlação intraclasse de 0,89. As análises fatorial exploratória e confirmatória revelaram um bom ajuste ao modelo previamente estabelecido de duas dimensões. As escalas de Saúde Física Global e Saúde Mental Global apresentaram uma boa cobertura do traço latente, de acordo com o Modelo de Resposta Gradual. Os itens Saúde Global do PROMIS para a língua portuguesa apresentaram equivalência em relação à versão original e propriedades psicométricas satisfatórias para a aplicação direcionada à população brasileira na prática clínica e em pesquisas.

scholarly journals AB0732 FATIGUE ASSESSMENT IN EGYPTIAN PSORIATIC ARTHRITIS PATIENTS: RELATION TO SERUM INTERLEUKIN 23, DISEASE ACTIVITY AND QUALITY OF LIFE.

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1660-1660
Author(s):  
N. Aboeladl ◽  
N. Elsawy ◽  
M. Helal ◽  
M. Elshafei ◽  
N. Lewis
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis ◽  
Chronic Illness ◽  
Disease Activity ◽  
Physical Function ◽  
Functional Assessment ◽  
Fatigue Score ◽  
Chronic Illness Therapy ◽  
Sf 36

Background:Fatigue is a prevalent and fundamental phenomenon in psoriatic arthritis (PsA) patients. It often interferes with physical and social functions and may lead to social withdrawal, long-standing sick leave, disability and loss of work productivity. Fatigue is a prevalent symptom in patients with chronic rheumatic diseases. Cytokines as interleukin IL-23/17 play a pivotal role in the pathogenesis of PsA.Objectives:To assess fatigue in PsA patients and determine its relation to serum IL 23 levels, disease activity, Skin severity, physical function and quality of life (QoL).Methods:Fifty PsA patients and 46 matched healthy controls were included in this study. Skin severity based on the Psoriasis Area and Severity Index (PASI), the Disease Activity index for Psoriatic Arthritis (DAPSA) and the Functional Assessment of Chronic Illness Therapy (FACIT-F) were assessed. Physical function was assessed by the Health Assessment Questionnaire Disability Index (HAQ-DI) and health-related QoL was assessed using the Short Form Health Survey (SF-36), Psoriatic Arthritis QoL (PsAQoL) and the Dermatology Life Quality Index (DLQI). Serum IL-23 levels were measured in the studied groups.Results:The study included 23 (46%) females and 27 (54%) males with a mean age of 42.78±12.33 years. The mean serum IL-23 level was significantly higher in PsA patients (50.89 ±13.86 pg/ml) than in controls (43.88 ± 6.34 pg/ml) (p=0.006). The FACIT score ranged from 2-41. Severe fatigue (score <30) was reported in 27 (54%) PsA patients. There were significant correlations between FACIT-F and (DAPSA, PASI, HAQ-DI, PsAQoL, DLQI and SF-36). No significant correlations could be detected between FACIT-F and serum levels of IL-23 and CRP.Conclusion:Fatigue was a frequent complaint in PsA patients. There was a mutual negative impact between fatigue and each of PsA joint disease activity and physical function and it worsened the QoL. Fatigue was worsened with increased severity of skin PsO. Although serum level of IL-23 was significantly elevated in PsA patients than the controls, it wasn’t correlated with fatigue score. Hence IL-23 can’t be considered a biomarker for fatigue severity.References:[1]Chandran V, Bhella S, Schentag C, Gladman DD. Functional Assessment of Chronic Illness Therapy-Fatigue Scale is valid in patients with psoriatic arthritis. Ann Rheum Dis 2007; 66(7):936.[2]Mortada M, Abdul-Sattar A, Gossec L. Fatigue in Egyptian patients with rheumatic diseases: a qualitative study. Health Qual Life Outcomes 2015; 13:134.[3]Krajewska-Wlodarczyk M, Owczarczyk-Saczonek A, Placek W. Fatigue - an underestimated symptom in psoriatic arthritis. Reumatologia 2017; 55(3):125-30.[4]Strand V, Mease P, Gossec L, Elkayam O, van den Bosch F, Zuazo J, et al. Secukinumab improves patient-reported outcomes in subjects with active psoriatic arthritis: results from a randomised phase III trial (FUTURE 1). Ann Rheum Dis 2017; 76(1):203-7.[5]Reygaerts T, Mitrovic S, Fautrel B, Gossec L. Effect of biologics on fatigue in psoriatic arthritis: A systematic literature review with meta-analysis. Joint Bone Spine 2018; 85(4):405-10.Table.Correlation between FACIT-F score and different parameters in patients groupFACIT-FrspDAPSA-0.365*0.009*PASI-0.424*0.002*HAQ-DI-0.464*0.001*PsAQoL-0.633*<0.001*DLQI-0.492*<0.001*SF-360.600*<0.001*CRP-0.1670.247Serum IL-23 levels-0.1830.204rs: Spearman coefficient, *: Statistically significant at p ≤ 0.05Figure. Correlation between FACIT-F and DAPSA in the studied PsA patients.Acknowledgments:I am deeply indebted to my late Professor Abdelmoniem Helal for his expert guidance and keen interest throughout the work.Thanks to My parents and Husband.Disclosure of Interests:None declared

Functional Assessment of Chronic Illness Therapy--Spiritual Personal Well-being; Czech Version

2018 ◽  
Author(s):  
Gabriela Šarníková ◽  
Klára Maliňáková ◽  
Jana Fürstová ◽  
Eva Dubovská ◽  
Peter Tavel
Keyword(s):  
Chronic Illness ◽  
Functional Assessment ◽  
Well Being ◽  
Chronic Illness Therapy
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