Antihyperglycemic and Antihyperlipidemic Effects of Aqueous and Ethanolic Leaf Extracts of Vitex doniana in Streptozotocin-induced Diabetic Rats

2014 ◽  
Vol 8 (4) ◽  
pp. 178-186
Author(s):  
Okpe Oche ◽  
Ibrahim Sani ◽  
Njoku Godwin Chiaka ◽  
Ndidi Uche Samuel
2018 ◽  
Vol 16 (12) ◽  
pp. 2919
Author(s):  
Uwakwe S Onoja ◽  
Innocent E Nweze ◽  
Nwachukwu Ekere ◽  
Philip F Uzor ◽  
Onyinyechi B Giginna

2018 ◽  
Vol 23 (4) ◽  
pp. 1-8
Author(s):  
Weleh, Ikechukwu Iyke ◽  
I. Green, Kinikanwo ◽  
Njoku, Bestman ◽  
Oriji, Vadunume Kingsley

2014 ◽  
Vol 05 (04) ◽  
pp. 340-348 ◽  
Author(s):  
I. A. Iwara ◽  
G. O. Igile ◽  
I. P. Ogar ◽  
O. E. Mboso ◽  
U. P. Ujong ◽  
...  

2015 ◽  
Vol 10 (2) ◽  
pp. 461
Author(s):  
Ponnusamy Revathi ◽  
Thangaraj Parimelazhagan

<p>Assessing the antidiabetic potential of <em>Acalypha alnifolia</em> is the main objective of the present study. Two doses of leaf extracts were treated with streptozotocin-induced diabetic rats for 21 days. The glucose level, insulin level, plasma lipids, total protein, electrolytes and plasma enzymes were monitored. The acetone extract of 400 mg/kg had potentiated to diminish the glucose and lipid level as well as other diabetic complications. Internal structures of pancreas were studied by histopathological sections and insulin expression was also observed by immunohistochemical study. Though the extracts having good antioxidant capability it might have to reduce the beta cell destruction or helps to repair it. The result of the toxicity analysis, histopathology and insulin expression supports the acetone extract. The present study attesting the antidiabetic properties of<em> A. alnifolia</em> hence this plant would be focused and taken for cultivation leads to add in human diet for getting therapeutic benefit.   </p><p> </p>


Sign in / Sign up

Export Citation Format

Share Document