scholarly journals Intake of fruit, berries, and vegetables and risk of type 2 diabetes in Finnish men: the Kuopio Ischaemic Heart Disease Risk Factor Study

2013 ◽  
Vol 99 (2) ◽  
pp. 328-333 ◽  
Author(s):  
Jaakko Mursu ◽  
Jyrki K Virtanen ◽  
Tomi-Pekka Tuomainen ◽  
Tarja Nurmi ◽  
Sari Voutilainen
Keyword(s):  
Type 2 Diabetes ◽  
Risk Factor ◽  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Disease Risk ◽  
Disease Risk Factor ◽  
Risk Factor Study ◽  
Factor Study ◽  
Heart Disease Risk

scholarly journals Intake of different dietary proteins and risk of type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study

2017 ◽  
Vol 117 (6) ◽  
pp. 882-893 ◽  
Author(s):  
Heli E. K. Virtanen ◽  
Timo T. Koskinen ◽  
Sari Voutilainen ◽  
Jaakko Mursu ◽  
Tomi-Pekka Tuomainen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Risk Factor ◽  
Heart Disease ◽  
Disease Risk ◽  
Dietary Proteins ◽  
Disease Risk Factor ◽  
Risk Factor Study ◽  
Factor Study ◽  
Heart Disease Risk

AbstractThe roles of different dietary proteins in the aetiology of type 2 diabetes (T2D) remain unclear. We investigated the associations of dietary proteins with the risk of incident T2D in Finnish men from the prospective Kuopio Ischaemic Heart Disease Risk Factor Study. The study included 2332 men aged 42–60 years at the baseline examinations in 1984–1989. Protein intakes were calculated from 4-d dietary records. Incident T2D was determined by self-administered questionnaires, fasting blood glucose measurements, 2-h oral glucose tolerance tests, and with national registers. The multivariable-adjusted risk of T2D on the basis of protein intakes was compared by the Cox proportional hazard ratios (HR). During the mean follow-up of 19·3 years, 432 incident T2D cases were identified. Total, animal, meat or dairy product protein intakes were not associated with risk of T2D when the potential confounders were accounted for. Plant (multivariable-adjusted extreme-quartile HR 0·65; 95 % CI 0·42, 1·00; Ptrend 0·04) and egg (HR 0·67; 95 % CI 0·44, 1·00; Ptrend 0·03) protein intakes were associated with a decreased risk of T2D. Adjustments for BMI, plasma glucose and serum insulin slightly attenuated associations. Replacing 1 % energy from carbohydrates with energy from protein was associated with a 5 % (95 % CI 0, 11) increased risk of T2D, but adjustment for fibre intake attenuated the association. Replacing 1 % of energy from animal protein with energy from plant protein was associated with 18 % (95 % CI 0, 32) decreased risk of T2D. This association remained after adjusting for BMI. In conclusion, favouring plant and egg proteins appeared to be beneficial in preventing T2D.

Risk Factors for Carotid Atherosclerosis: The Kuopio Ischaemic Heart Disease Risk Factor Study

1989 ◽  
Vol 21 (3) ◽  
pp. 227-229 ◽  
Author(s):  
Jukka T. Salonen ◽  
Kari Seppänen ◽  
Rainer Rauramaa ◽  
Riitta Salonen
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Carotid Atherosclerosis ◽  
Disease Risk ◽  
Disease Risk Factor ◽  
Risk Factor Study ◽  
Factor Study ◽  
Heart Disease Risk

scholarly journals Arginine intake, blood pressure, and the incidence of acute coronary events in men: the Kuopio Ischaemic Heart Disease Risk Factor Study

2002 ◽  
Vol 76 (2) ◽  
pp. 359-364 ◽  
Author(s):  
Birgitta Venho ◽  
Sari Voutilainen ◽  
Veli-Pekka Valkonen ◽  
Jyrki Virtanen ◽  
Timo A Lakka ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Disease Risk ◽  
Disease Risk Factor ◽  
Risk Factor Study ◽  
Factor Study ◽  
Coronary Events ◽  
Heart Disease Risk

scholarly journals Intake of flavonoids and risk of cancer in Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study

2008 ◽  
Vol 123 (3) ◽  
pp. 660-663 ◽  
Author(s):  
Jaakko Mursu ◽  
Tarja Nurmi ◽  
Tomi-Pekka Tuomainen ◽  
Jukka T. Salonen ◽  
Eero Pukkala ◽  
...  
Keyword(s):  
Risk Factor ◽  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Disease Risk ◽  
Disease Risk Factor ◽  
Risk Factor Study ◽  
Factor Study ◽  
Risk Of Cancer ◽  
Heart Disease Risk

scholarly journals Dietary intake of choline and phosphatidylcholine and risk of type 2 diabetes in men: The Kuopio Ischaemic Heart Disease Risk Factor Study

2020 ◽  
Vol 59 (8) ◽  
pp. 3857-3861 ◽  
Author(s):  
Jyrki K. Virtanen ◽  
Tomi-Pekka Tuomainen ◽  
Sari Voutilainen
Keyword(s):  
Type 2 Diabetes ◽  
Risk Factor ◽  
Disease Risk ◽  
Diabetes Diagnosis ◽  
Disease Risk Factor ◽  
Risk Factor Study ◽  
Factor Study ◽  
Choline Intake ◽  
Heart Disease Risk

Abstract Purpose To investigate associations of total dietary choline intake and its major dietary form, phosphatidylcholine, with type 2 diabetes risk. Methods We included 2332 men aged 42–60 years at baseline in 1984–1989 from the Kuopio Ischaemic Heart Disease Risk Factor Study in eastern Finland. Dietary intakes were assessed with 4-d food recording at baseline. Type 2 diabetes diagnosis was based on self-administered questionnaires, fasting and 2-h oral glucose tolerance test blood glucose measurements, or by record linkage to national health registries. Multivariable-adjusted Cox proportional hazards regression models were used for statistical analysis. Results During the mean 19.3-year follow-up, 432 men had type 2 diabetes diagnosis. After multivariable adjustments, those in the highest vs. lowest choline intake quartile had 25% (95% CI 2–43%) lower relative risk (P trend across quartiles = 0.02) and those in the highest vs. lowest phosphatidylcholine quartile had 41% (95% CI 22–55%) lower relative risk (P trend < 0.001) of type 2 diabetes. Conclusions Higher choline intake, especially phosphatidylcholine, was associated with lower type 2 diabetes risk among men.

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