Evidence of an Intra-Plate "Hot-Spot" Under the Ecuadorian Oriente Basin During the Cretaceous Tectonic Evolution

1997 ◽  
Author(s):  
R. Barragan ◽  
F. Ramirez ◽  
J. Rodas ◽  
P. Baby
Keyword(s):  
Tectonic Evolution ◽  
Hot Spot

Evolution of Nigeria's Benue Trough (Aulacogen): a tectonic model

1975 ◽  
Vol 112 (6) ◽  
pp. 575-583 ◽  
Author(s):  
M. A. Olade
Keyword(s):  
Atlantic Ocean ◽  
Tectonic Evolution ◽  
Hot Spot ◽  
Continental Drift ◽  
South Atlantic ◽  
South Atlantic Ocean ◽  
Plate Tectonic ◽  
Mantle Upwelling ◽  
Benue Trough ◽  
Tectonic Model

SummaryThe tectonic evolution of Nigeria's Benue Trough has recently been the focus of investigations, especially in relation to continental drift and opening of the South Atlantic Ocean during Cretaceous times. Most of the tectonic models presented for the Benue depression have placed undue emphasis on certain plate tectonic concepts which are inconsistent with the salient geologic features of the trough. A possible model, involving the rise and cessation of mantle upwelling beneath a Cretaceous hot spot, and attendant patterns of doming, rifting, sedimentation, magmatism and tectonism, is proposed for the Benue aulacogen.

Mutation Spectrum in Patients with Wiskott-Aldrich Syndrome and X-linked Thrombocytopenia: Identification of Twelve Different Mutations in the WASP Gene

1996 ◽  
Vol 75 (04) ◽  
pp. 546-550 ◽  
Author(s):  
Marianne Schwartz ◽  
Albert Békássy ◽  
Mikael Donnér ◽  
Thomas Hertel ◽  
Stefan Hreidarson ◽  
...  
Keyword(s):  
Base Pair ◽  
Hot Spot ◽  
Missense Mutations ◽  
Nucleotide Substitutions ◽  
Exon 2 ◽  
Wiskott Aldrich Syndrome ◽  
Base Pair Deletion ◽  
Reliable Diagnosis ◽  
Wasp Gene ◽  
Detection Of Mutations

SummaryTwelve different mutations in the WASP gene were found in twelve unrelated families with Wiskott-Aldrich syndrome (WAS) or X-linked thrombocytopenia (XLT). Four frameshift, one splice, one nonsense mutation, and one 18-base-pair deletion were detected in seven patients with WAS. Only missense mutations were found in five patients diagnosed as having XLT. One of the nucleotide substitutions in exon 2 (codon 86) results in an Arg to Cys replacement. Two other nucleotide substitutions in this codon, R86L and R86H, have been reported previously, both giving rise to typical WAS symptoms, indicating a mutational hot spot in this codon. The finding of mutations in the WASP gene in both WAS and XLT gives further evidence of these syndromes being allelic. The relatively small size of the WASP gene facilitates the detection of mutations and a reliable diagnosis of both carriers and affected fetuses in families with WAS or XLT.

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