scholarly journals Development and Characterization of Monoclonal Antibodies against Nucleoprotein for Diagnosis of Influenza A Virus

2018 ◽  
Vol 28 (5) ◽  
pp. 809-815 ◽  
Author(s):  
Nguyen Hong Phuong ◽  
Chaewon Kwak ◽  
Chang-Kyu Heo ◽  
Eun Wie Cho ◽  
Jihyun Yang ◽  
...  
2013 ◽  
Vol 87 (15) ◽  
pp. 8272-8281 ◽  
Author(s):  
N. S. Heaton ◽  
V. H. Leyva-Grado ◽  
G. S. Tan ◽  
D. Eggink ◽  
R. Hai ◽  
...  

2013 ◽  
Vol 288 (16) ◽  
pp. 11013-11023 ◽  
Author(s):  
Yong Liu ◽  
Kun Qin ◽  
Geng Meng ◽  
Jinfang Zhang ◽  
Jianfang Zhou ◽  
...  

2009 ◽  
Vol 90 (7) ◽  
pp. 1730-1733 ◽  
Author(s):  
Natalia L. Varich ◽  
Konstantin S. Kochergin-Nikitsky ◽  
Evgeny V. Usachev ◽  
Olga V. Usacheva ◽  
Alexei G. Prilipov ◽  
...  

The locations of amino acid positions relevant to antigenic variation in the nucleoprotein (NP) of influenza virus are not conclusively known. We analysed the antigenic structure of influenza A virus NP by introducing site-specific mutations at amino acid positions presumed to be relevant for the differentiation of strain differences by anti-NP monoclonal antibodies. Mutant proteins were expressed in a prokaryotic system and analysed by performing ELISA with monoclonal antibodies. Four amino acid residues were found to determine four different antibody-binding sites. When mapped in a 3D X-ray model of NP, the four antigenically relevant amino acid positions were found to be located in separate physical sites of the NP molecule.


2012 ◽  
Vol 155 (2-4) ◽  
pp. 409-416 ◽  
Author(s):  
Zhan Guang-jian ◽  
Ling Zong-shuai ◽  
Zhu Yan-li ◽  
Jiang Shi-jin ◽  
Xie Zhi-jing

2018 ◽  
Vol 9 (10) ◽  
pp. 5198-5208 ◽  
Author(s):  
Hanjie Yu ◽  
Yaogang Zhong ◽  
Zhiwei Zhang ◽  
Xiawei Liu ◽  
Kun Zhang ◽  
...  

The bovine milk proteins have a wide range of functions, but the role of the attached glycans in their biological functions has not been fully understood yet.


2011 ◽  
Vol 85 (24) ◽  
pp. 13463-13467 ◽  
Author(s):  
M. Terajima ◽  
J. Cruz ◽  
M. D. T. Co ◽  
J.-H. Lee ◽  
K. Kaur ◽  
...  

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