scholarly journals GENECFE-ANFIS: A NEURO-FUZZY INFERENCE SYSTEM TO INFER GENE-GENE INTERACTIONS BASED ON RECOGNITION OF MICROARRAY GENE EXPRESSION PATTERNS

2007 ◽  
Vol 19 (02) ◽  
pp. 71-78 ◽  
Author(s):  
Cheng-Long Chuang ◽  
Chung-Ming Chen ◽  
Grace S. Shieh ◽  
Joe-Air Jiang

A neuro-fuzzy inference system that recognizes the expression patterns of genes in microarray gene expression (MGE) data, called GeneCFE-ANFIS, is proposed to infer gene interactions. In this study, three primary features are utilized to extract genes' expression patterns and used as inputs to the neuro-fuzzy inference system. The proposed algorithm learns expression patterns from the known genetic interactions, such as the interactions confirmed by qRT-PCR experiments or collected through text-mining technique by surveying previously published literatures, and then predicts other gene interactions according to the learned patterns. The proposed neuro-fuzzy inference system was applied to a public yeast MGE dataset. Two simulations were conducted and checked against 112 pairs of qRT-PCR confirmed gene interactions and 77 TFs (Transcriptional Factors) pairs collected from literature respectively to evaluate the performance of the proposed algorithm.

2018 ◽  
Vol 2018 (1) ◽  

Microarray is a technology that enables simultaneously analysis of thousands of genes in DNA structure depending on the advances in biochemistry. With this technology, it has become possible to diagnose and treat heredity diseases by analyzing thousands of gene expression levels. This study proposes an artificial intelligence method, Adaptive neuro-fuzzy inference system (ANFIS), to classify cancer gene expression profiles. The findings obtained with the proposed ANFIS approach are compared with the results of statistical methods such as Naive Bayes and Support Vector Machines. In conclusion, although the highest average classification performance achieved with ANFIS is 95.56%, the highest performance achieved with statistical methods are found to be 87.65%.


2013 ◽  
Vol 8 (4) ◽  
pp. 155892501300800 ◽  
Author(s):  
A.R. Fallahpour ◽  
A.R. Moghassem

This study compares capabilities of two different modelling methodologies for predicting breaking strength of rotor spun yarns. Forty eight yarn samples were produced considering variations in three drawing frame parameters namely break draft, delivery speed, and distance between back and middle rolls. Several topologies with different architectures were trained to get the best adaptive neuro-fuzzy inference system (ANFIS) and gene expression programming (GEP) models. Prediction performance of the GEP model was compared with that of ANFIS using root mean square error (RMSE) and correlation coefficient (R2-Value) parameters on the test data. Results show that, the GEP model has a significant priority over the ANFIS model in term of prediction accuracy. The correlation coefficient (R2-value) and root mean square error for the GEP model were 0.87 and 0.35 respectively, while these parameters were 0.48 and 0.53 for the ANFIS model. Also, a mathematical formula was developed with high degree of accuracy using GEP algorithm to predict the breaking strength of the yarns. This advantage is not accessible in the ANFIS model.


2018 ◽  
Vol 35 (5) ◽  
pp. 2078-2106 ◽  
Author(s):  
Ehsan Sadrossadat ◽  
Behnam Ghorbani ◽  
Rahimzadeh Oskooei ◽  
Mahdi Kaboutari

Purpose This study aims to examine the potential of two artificial intelligence (AI)-based algorithms, namely, adaptive neuro-fuzzy inference system (ANFIS) and gene expression programming (GEP), for indirect estimation of the ultimate bearing capacity (qult) of rock foundations, which is a considerable civil and geotechnical engineering problem. Design/methodology/approach The input-processing-output procedures taking place in ANFIS and GEP are represented for developing predictive models. The great importance of simultaneously considering both qualitative and quantitative parameters for indirect estimation of qult is taken into account and explained. This issue can be considered as a remarkable merit of using AI-based approaches. Furthermore, the evaluation procedure of various models from both engineering and accuracy viewpoints is also demonstrated in this study. Findings A new and explicit formula generated by GEP is proposed for the estimation of the qult of rock foundations, which can be used for further engineering aims. It is also presented that although the ANFIS approach can predict the output with a high degree of accuracy, the obtained model might be a black-box. The results of model performance analyses confirm that ANFIS and GEP can be used as alternative and useful approaches over previous methods for modeling and prediction problems. Originality/value The superiorities and weaknesses of GEP and ANFIS techniques for the numerical analysis of engineering problems are expressed and the performance of their obtained models is compared to those provided by other approaches in the literature. The findings of this research provide the researchers with a better insight to using AI techniques for resolving complicated problems.


2017 ◽  
Vol 3 (1) ◽  
pp. 36-48
Author(s):  
Erwan Ahmad Ardiansyah ◽  
Rina Mardiati ◽  
Afaf Fadhil

Prakiraan atau peramalan beban listrik dibutuhkan dalam menentukan jumlah listrik yang dihasilkan. Ini menentukan  agar tidak terjadi beban berlebih yang menyebabkan pemborosan atau kekurangan beban listrik yang mengakibatkan krisis listrik di konsumen. Oleh karena itu di butuhkan prakiraan atau peramalan yang tepat untuk menghasilkan energi listrik. Teknologi softcomputing dapat digunakan  sebagai metode alternatif untuk prediksi beban litrik jangka pendek salah satunya dengan metode  Adaptive Neuro Fuzzy Inference System pada penelitian tugas akhir ini. Data yang di dapat untuk mendukung penelitian ini adalah data dari APD PLN JAWA BARAT yang berisikan laporan data beban puncak bulanan penyulang area gardu induk majalaya dari januari 2011 sampai desember 2014 sebagai data acuan dan data aktual januari-desember 2015. Data kemudian dilatih menggunakan metode ANFIS pada software MATLAB versi b2010. Dari data hasil pelatihan data ANFIS kemudian dilakukan perbandingan dengan data aktual dan data metode regresi meliputi perbandingan anfis-aktual, regresi-aktual dan perbandingan anfis-regresi-aktual. Dari perbandingan disimpulkan bahwa data metode anfis lebih mendekati data aktual dengan rata-rata 1,4%, menunjukan prediksi ANFIS dapat menjadi referensi untuk peramalan beban listrik dimasa depan.


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