Transient Ischemic Attack

2022 ◽  
pp. 157-169
Author(s):  
Murat Guntel

The transient ischemic attack is a neurological emergency which is a clinical view of focal cerebral, retinal, or spinal dysfunction that lasts less than an hour, without any detectable acute infarction in neurological imaging methods. TIA is a serious warning for ischemic stroke, and this risk is particularly high in the first 48 hours. Following TIAs, approximately 10-15% of patients undergo stroke in 90 days and about half of these patients suffer a stroke in the first two days. Neuroimaging and laboratory studies should be performed quickly to reveal the etiology and to reduce the risk of stroke that may develop in patients present with TIA. Therapeutic and preventive interventions should be started as soon as possible. With early diagnosis and treatment, the risk of a 90-day stroke in these patients can be reduced by 80%. In addition to antiplatelet and anticoagulant treatments, aggressive control of blood pressure, regulation of blood sugar, statin, dietary recommendations, exercise, and managing the other underlying specific conditions should be started quickly.

2008 ◽  
Vol 30 (4) ◽  
pp. 348-355 ◽  
Author(s):  
Yilong Wang ◽  
Di Wu ◽  
Yong Zhou ◽  
Xingquan Zhao ◽  
Chunxue Wang ◽  
...  

Stroke ◽  
2011 ◽  
Vol 42 (12) ◽  
pp. 3612-3613 ◽  
Author(s):  
Michael T. Mullen ◽  
Brett L. Cucchiara

Background and Purpose— The recent redefinition of transient ischemic attack (TIA) reclassifies patients with acute infarction on magnetic resonance imaging as ischemic stroke. Redefinition will improve the prognosis of both TIA and ischemic stroke, an epidemiological paradox known as the Will Rogers phenomenon. We sought to quantify the impact of this phenomenon. Methods— Incidence of TIA, risk of death/disability after stroke, rate of acute infarction on magnetic resonance imaging after TIA, and 90-day stroke risk after TIA with and without infarction on magnetic resonance imaging were determined based on published data. The impact on poststroke disability in the redefined cohort of patients with ischemic stroke was computed. A sensitivity analysis was performed to account for uncertainty in input variables. Results— Using the new TIA definition, the 90-day risk of stroke following TIA is 1%. In the United States, redefinition will increase annual ischemic stroke incidence from 691 650 to 747 755 and result in a 3.4% absolute reduction in poststroke disability. In a sensitivity analysis, this risk reduction varies from 1.5 to 6.5%, and is most dependent on the incidence of TIA. Conclusions— Redefinition of TIA reduces stroke risk after TIA to approximately 1% at 90 days, and reduces the rate of poststroke disability by approximately 3.4%.


Author(s):  
Nanxiang Ouyang ◽  
Chuning Shi ◽  
Xiaofan Guo ◽  
Yihan Chen ◽  
Yingxian Sun

CHEST Journal ◽  
2009 ◽  
Vol 136 (4) ◽  
pp. 102S
Author(s):  
Kaushang Gandhi ◽  
Wilbert S. Aronow ◽  
Chandrasekar Palaniswamy ◽  
Harshad Amin ◽  
Harit Desai ◽  
...  

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