Reaching an AIDS-Free Generation in Côte d'Ivoire, Data Driven Policy Design for HIV/AIDS Response Programs

2016 ◽  
Vol 5 (1) ◽  
pp. 43-62 ◽  
Author(s):  
Paulo Gonçalves ◽  
Simplice Takoubo Kamdem

Sub-Saharan Africa is home to 24.7 million people living with HIV of an estimated total of 35.0 million people globally in 2013. It also accounts for almost 70% of the new HIV infections globally. In West Africa, Cote d'Ivoire has the highest HIV prevalence, or 3.7% of the 2012 population, and the two virus types (HIV-1 & HIV-2) are present. From an epidemiological standpoint, these unique attributes make Cote d'Ivoire unique. At the same time, existing HIV/AIDS modeling policies have being developed from the data of countries that do not have these peculiarities. This research develops a formal system dynamics model capturing the evolution of HIV/AIDS in Cote d'Ivoire for four decades, starting in 1990. The findings include a development of HIV/AIDS behavior pattern over time that led to the proposal of evidence-based policies.

Author(s):  
Mamadou Sanogo

Ivorian-Moroccan relations are not new because the diplomatic relations between the two countries have been established since August 16, 1962, but the interest of Morocco for Côte d'Ivoire has considerably strengthened during the royal visit of 19-21 March 2013 in Côte d'Ivoire, the first, since the beginning of his reign in 1999. Morocco is now refocusing its foreign policy on sub-Saharan Africa after the failure of Maghreb integration. This rapprochement resulted in Morocco's return to the African Union and its accession to ECOWAS.


Parasitology ◽  
2019 ◽  
Vol 147 (3) ◽  
pp. 287-294 ◽  
Author(s):  
Etienne K. Angora ◽  
Jean-François Allienne ◽  
Olivier Rey ◽  
Hervé Menan ◽  
André O. Touré ◽  
...  

AbstractSchistosomiasis is a neglected tropical disease, though it is highly prevalent in many parts of sub-Saharan Africa. While Schistosoma haematobium-bovis hybrids have been reported in West Africa, no data about Schistosoma hybrids in humans are available from Côte d'Ivoire. This study aimed to identify and quantify S. haematobium-bovis hybrids among schoolchildren in four localities of Côte d'Ivoire. Urine samples were collected and examined by filtration to detect Schistosoma eggs. Eggs were hatched and 503 miracidia were individually collected and stored on Whatman® FTA cards for molecular analysis. Individual miracidia were molecularly characterized by analysis of mitochondrial cox1 and nuclear internal transcribed spacer 2 (ITS 2) DNA regions. A mitochondrial cox1-based diagnostic polymerase chain reaction was performed on 459 miracidia, with 239 (52.1%) exhibiting the typical band for S. haematobium and 220 (47.9%) the S. bovis band. The cox1 and ITS 2 amplicons were Sanger sequenced from 40 randomly selected miracidia to confirm species and hybrids status. Among the 33 cox1 sequences analysed, we identified 15 S. haematobium sequences (45.5%) belonging to seven haplotypes and 18 S. bovis sequences (54.5%) belonging to 12 haplotypes. Of 40 ITS 2 sequences analysed, 31 (77.5%) were assigned to pure S. haematobium, four (10.0%) to pure S. bovis and five (12.5%) to S. haematobium-bovis hybrids. Our findings suggest that S. haematobium-bovis hybrids are common in Côte d'Ivoire. Hence, intense prospection of domestic and wild animals is warranted to determine whether zoonotic transmission occurs.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
J C Guinan ◽  
G D Meless ◽  
A D Sangaré ◽  
V Danho-Da ◽  
B S Kouassi ◽  
...  

Abstract Background Despite several decades of fighting HIV infection, discrimination against people living with this infection persists, even among health professionals. Understanding the determinants of discriminatory attitudes of dentists is a first step towards access to oral health care and improved care for people living with HIV (PLHIV). Objectives To analyse the determinants of discriminatory attitudes towards people living with HIV among dentists in Côte d’Ivoire. Methods A cross-sectional survey was conducted among dentists in Abidjan in 2016. In addition to socio-professional characteristics, a questionnaire collected information on their knowledge about HIV (transmission, hiv-related oral diseases) and their individual perception (fear of being contaminated, cross-contamination...). The chi2 test for independent sampling was used to identify factors associated with discriminatory attitudes (threshold α = 5%). Results A total of 120 dentists were interviewed: 61.3% from the public sector; 56.7% men; 54.2% in couple; 53.3% had participated in continuing education on HIV; 29.2% did not know HIV-related diseases and transmission modes and 69.2% reported fear of being infected during care; 44.2% reported informing staff of the patient’s HIV status. The proportion of dentists with discriminatory attitudes was estimated at 69.2%. The main associated factors were: female gender (p = 0.001), living in couple (p = 0.000), lack of knowledge of the risk of HIV transmission after a blood exposure accident (p = 0.000), the law protecting people living with HIV in Côte d’Ivoire (p = 0.009) and fear of being infected (p = 0.000). Conclusions The results of this study show that the determinants of discriminatory attitudes among dentists result from their lack of knowledge of the disease, justifying the need to strengthen their continuing education on HIV/AIDS infection. Key messages Dentists discrimination towards people living with HIV infection result from their lack of knowledge about the infection. It’s essential to strengthen their knowledge about HIV in order to improve access to care for people living with HIV.


2019 ◽  
Vol 21 (Supplement_D) ◽  
pp. D47-D49 ◽  
Author(s):  
Kramoh Kouadio Euloge ◽  
Ekoua Daniel ◽  
Abina Audrey ◽  
Koffi Kouassi Florent ◽  
Koffi Djinguin Ben Justin ◽  
...  

1993 ◽  
Vol 31 (1) ◽  
pp. 67-92 ◽  
Author(s):  
Catherine Boone

Côte D'Ivoire retains a central place in discussions on the development of African capitalism. Dramatic increases in agricultural and industrial production in the post-colonial period, coupled with the régime's unequivocally liberal and pro-capitalist discourse, contributed to the image of the Ivoirian state as aggressively promoting the expansion of local and foreign capital. By the late 1970s, it was clear that a select stratum of Ivoirians had amassed private fortunes in the industrial sector, agro-industry, and real estate. Less clear is the significance of this fact for understanding the internal dynamics and development trajectory of Ivoirian capitalism. The idea that the Ivoirian bourgeoisie diversified from its base in agriculture to become one of the most dynamic and influential business classes in sub-Saharan Africa remains plausible, but it evokes no consensus among analysts. Indeed, students of Ivoirian capitalism have been more inclined to argue that the state itself remains the main source of private fortunes, that local capital is thoroughly subordinated to foreign capital, and that indigenous business interests are ensnared in the clientelistic networks of the régime.


2021 ◽  
Vol 16 (2) ◽  
Author(s):  
Seïdinan I. Traoré ◽  
Louise Y. Achi ◽  
Stefanie J. Krauth ◽  
Moussa Sanogo ◽  
Jakob Zinsstag ◽  
...  

Fascioliasis, caused by an infection with liver flukes of the genus Fasciola, is an important disease of livestock in most parts of the world. However, little is known about the distribution of fascioliasis in sub-Saharan Africa. We report results of a cross-sectional study conducted in 2014 in the district des Savanes in the northern part of Côte d’Ivoire. We obtained 275 livers from bovine suspected with fascioliasis and 51 unsuspected livers from 24 slaughterhouses. Livers were dissected using a standard operating procedure and all Fasciola gigantica flukes were removed from the tissues of the liver and the biliary ducts. We found F. gigantica in 125 livers from bovines suspected with fascioliasis (45.5%) in 10 departments of the district des Savanes. Among the unsuspected livers, five were positive for F. gigantica (9.8%). The distribution of fascioliasis showed considerable spatial heterogeneity, both at regional (ranging from 18.0% to 52.3%) and departmental level (ranging from 14.3% to 64.0%). Poro region was the most affected (52.3%) with a relatively homogeneous distribution. The departments most affected by fascioliasis were M’Bengué (64.0%), Sinématiali (62.1%) and Ferkessédougou (52.9%). Our study confirms that fascioliasis is an important veterinary disease in the northern part of Côte d’Ivoire, and hence, high-risk areas need to be targeted for prevention and control measures.


2021 ◽  
Author(s):  
Etilé Augustin Anoh ◽  
Grit Schubert ◽  
Oby Wayoro ◽  
Monemo Pacôme ◽  
Essia Belarbi ◽  
...  

SARS-CoV-2 variants of concern (VOC) and variants of interest (VOI) are heavily altering the COVID-19 pandemic's course due to their increased transmissibility, virulence and immune escape abilities. Data on their spread in western sub-Saharan Africa is however still scarce. We therefore sequenced viral genomes from SARS-CoV-2 cases identified in central and northern Côte d'Ivoire between May 2020 and March 2021. We report the introduction of VOC B.1.1.7 as early as mid-January 2021, followed by detection of a single case of VOC B.1.351, as well as VOI B.1.525. Since early 2021 VOC/VOI are gradually dominating the SARS-CoV-2 virus pool in Côte d'Ivoire, as seen in other regions of the world. Intriguingly, we also find that another lineage, A.27, has also been on the rise over the same period. In sum, this study highlights again the extremely rapid local diffusion of VOC, VOI and possibly A.27, and the importance of further reinforcing capacities for genomic surveillance on the African continent.


2017 ◽  
Vol 2 ◽  
pp. 8 ◽  
Author(s):  
Mouhamadou Chouaïbou ◽  
Fodjo Behi Kouadio ◽  
Emmanuel Tia ◽  
Luc Djogbenou

Background. The intensive use of insecticides in public health and agriculture has led to the development of insecticide resistances in malaria vectors across sub-Saharan Africa countries in the last two decades. The kdr target site point mutation which is among the best characterised resistance mechanisms seems to be changing its distribution patterns on the African continent. The 1014F kdr mutation originally described only in West Africa is spreading to East Africa while the 1014S kdr mutation originally described in East Africa, is spreading to West and Central Africa. However, the East-kdr mutation has not been reported in Côte d'Ivoire so far. Methods. Immature stages of Anopheles gambiae s.l. were collected from breeding sites at the outskirts of Yamoussoukro, Côte d'Ivoire. Emerging 3–5 day old adult female mosquitoes were tested for susceptibility to deltamethrin 0.05%, malathion 5%, bendiocarb 1% and dichlorodiphenyltrichloroethane (DDT) 4% according to WHO standard procedures. A total of 50 An. gambiae s.l. specimens were drawn at random for DNA extraction and identification down to the species level. A subsample of 30 mosquitoes was tested for the East-African kdr mutation using a Taqman assay. Results. The tested mosquito population appeared to be strongly resistant to deltamethrin (1.03% mortality), bendiocarb (38.46% mortality) and DDT (0% mortality) with probable resistance observed for malathion (92.47%). Among the 41 mosquitoes that were successfully characterized, An. coluzzii was predominant (68.3%) followed by An. gambiae s.s. (19.5%) and a few hybrids (7.3%). Out of 30 specimens genotyped for East-kdr, a single hybrid mosquito appeared to be heterozygous for the mutation. Conclusion. The present study revealed the presence of the East-kdr mutation in Côte d’Ivoire for the first time in An. gambiae and highlights the urgent need to start monitoring the allele and genotype frequencies.


Author(s):  
Hermann Yao ◽  
Arnaud Ekou ◽  
Thierry Niamkey ◽  
Sandra Hounhoui Gan ◽  
Isabelle Kouamé ◽  
...  

Background Data in the literature on acute coronary syndrome in sub‐Saharan Africa are scarce. Methods and Results We conducted a systematic review of the MEDLINE (PubMed) database of observational studies of acute coronary syndrome in sub‐Saharan Africa from January 1, 2010 to June 30, 2020. Acute coronary syndrome was defined according to current definitions. Abstracts and then the full texts of the selected articles were independently screened by 2 blinded investigators. This systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta‐Analyses standards. We identified 784 articles with our research strategy, and 27 were taken into account for the final analysis. Ten studies report a prevalence of acute coronary syndrome among patients admitted for cardiovascular disease ranging from 0.21% to 22.3%. Patients were younger, with a minimum age of 52 years in South Africa and Djibouti. There was a significant male predominance. Hypertension was the main risk factor (50%–55% of cases). Time to admission tended to be long, with the longest times in Tanzania (6.6 days) and Burkina Faso (4.3 days). Very few patients were admitted by medicalized transport, particularly in Côte d'Ivoire (only 34% including 8% by emergency medical service). The clinical presentation is dominated by ST–elevation sudden cardiac arrest. Percutaneous coronary intervention is not widely available but was performed in South Africa, Kenya, Côte d'Ivoire, Sudan, and Mauritania. Fibrinolysis was the most accessible means of revascularization, with streptokinase as the molecule of choice. Hospital mortality was highly variable between 1.2% and 24.5% depending on the study populations and the revascularization procedures performed. Mortality at follow‐up varied from 7.8% to 43.3%. Some studies identified factors predictive of mortality. Conclusions The significant disparities in our results underscore the need for a multicenter registry for acute coronary syndrome in sub‐Saharan Africa in order to develop consensus‐based strategies, propose and evaluate tailored interventions, and identify prognostic factors.


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