scholarly journals Avaliação da qualidade de vida e capacidade funcional de pacientes com câncer em tratamento quimioterápico/ Evaluation of quality of life and functional capacity of cancer patients in chemotherapy

2017 ◽  
Vol 16 (3) ◽  
Author(s):  
Victor Barros Costa ◽  
Carolina Ribeiro Camargo ◽  
Paulo Henrique Fernandes dos Santos ◽  
Luciano Ramos de Lima ◽  
Marina Morato Stival ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Functional Capacity ◽  
Performance Status ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
De Se ◽  
Distrito Federal

O presente estudo teve como objetivo avaliar a qualidade de vida relacionada a saúde (QVRS) e mensurar a capacidade funcional de pacientes com câncer nos momentos pré e pós-quimioterapia (QT). Trata‐se de um estudo de coorte, com abordagem quantitativa, realizado de janeiro a março de 2015 em um ambulatório de QT de um hospital universitário do Distrito Federal, contemplando uma amostra de 53 indivíduos. Os participantes foram entrevistados em dois momentos, acompanhando, respectivamente, o primeiro e segundo ciclos da QT, durante os quais foram aplicados o protocolo Quality of Life questionnaire-core 30 e as escalas de avaliação da capacidade funcional Performance Status e Escala de Desempenho de Karnofsky. Os resultados evidenciaram a diminuição de todas as funcionalidades após o primeiro ciclo da QT, além de diferenças significativas dos escores de: fadiga (p=0,003), náusea (p=<0,000), insônia (p=0,042) e diarreia (p=0,006), havendo um aumento significativo da ocorrência de sinais e sintomas entre o primeiro e o segundo ciclo de QT, de 9,4% para 20,8%. Neste intervalo, também foi constatada piora significativa no que diz respeito ao comprometimento funcional dos pacientes (p=0,045). Os resultados evidenciaram a necessidade de se observar o impacto na QVRS desde o início do tratamento quimioterápico.

Quality of Life in Head and Neck Cancer Patients: Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H&N35

1999 ◽  
Vol 17 (3) ◽  
pp. 1008-1008 ◽  
Author(s):  
Kristin Bjordal ◽  
Eva Hammerlid ◽  
Marianne Ahlner-Elmqvist ◽  
Alexander de Graeff ◽  
Morten Boysen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck ◽  
Cancer Patients ◽  
Performance Status ◽  
Compliance Rate ◽  
Life Questionnaire ◽  
European Organization ◽  
Quality Of Life Questionnaire ◽  
Eortc Qlq

PURPOSE: The aim of this study was to define the scales and test the validity, reliability, and sensitivity of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ)-H&N35, a questionnaire designed to assess the quality of life of head and neck (H&N) cancer patients in conjunction with the general cancer-specific EORTC QLQ-C30. PATIENTS AND METHODS: Questionnaires were given to 500 H&N cancer patients from Norway, Sweden, and the Netherlands as part of two prospective studies. The patients completed the questionnaires before, during (Norway and Sweden only), and after treatment, yielding a total of 2070 completed questionnaires. RESULTS: The compliance rate was high, and the questionnaires were well accepted by the patients. Seven scales were constructed (pain, swallowing, senses, speech, social eating, social contact, sexuality). Scales and single items were sensitive to differences between patient subgroups with relation to site, stage, or performance status. Most scales and single items were sensitive to changes, with differences of various magnitudes according to the site in question. The internal consistency, as assessed by Cronbach's alpha coefficient, varied according to assessment point and within subsamples of patients. A low overall alpha value was found for the speech and the senses scales, but values were higher in assessments of patients with laryngeal cancer and in patients with nose, sinus, and salivary gland tumors. Scales and single items in the QLQ-H&N35 seem to be more sensitive to differences between groups and changes over time than do the scales and single items in the core questionnaire. CONCLUSION: The QLQ-H&N35, in conjunction with the QLQ-C30, provides a valuable tool for the assessment of health-related quality of life in clinical studies of H&N cancer patients before, during, and after treatment with radiotherapy, surgery, or chemotherapy.

scholarly journals The EORTC Quality of Life Questionnaire for cancer patients ( QLQ ‐C30): Australian general population reference values

2019 ◽  
Vol 210 (11) ◽  
pp. 499-506 ◽  
Author(s):  
Rebecca Mercieca‐Bebber ◽  
Daniel SJ Costa ◽  
Richard Norman ◽  
Monika Janda ◽  
David P Smith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
General Population ◽  
Cancer Patients ◽  
Reference Values ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Eortc Quality

Validation of Cancer Institute Quality of Life Questionnaire Version II for cancer patients in India

2011 ◽  
Vol 48 (4) ◽  
pp. 500 ◽  
Author(s):  
E Vidhubala ◽  
R Ravikannan ◽  
R Muthuvel ◽  
FU John Paul ◽  
Latha ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Questionnaire Version

scholarly journals Validating an Instrument for Direct Patient Reporting of Distress and Chemotherapy-Related Toxicity among South African Cancer Patients

Cancers ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 95
Author(s):  
Charmaine L. Blanchard ◽  
Keletso Mmoledi ◽  
Michael H. Antoni ◽  
Georgia Demetriou ◽  
Maureen Joffe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Construct Validity ◽  
Cancer Patients ◽  
South African ◽  
Pearson Correlation ◽  
Performance Status ◽  
Summary Score ◽  
Life Questionnaire ◽  
Patient Reported

Patient-reported outcome measures (PROM) for monitoring treatment toxicity improve quality of life (QoL) and clinical outcomes. However, no such PROMs exist for sub-Saharan African cancer patients. We aimed to validate the Patient Reported Symptoms-South Africa (PRS-SA) survey, a novel PROM for measuring distress and chemotherapy-related symptoms in South African cancer patients. We enrolled patients at the oncology clinic at Charlotte Maxeke Hospital, Johannesburg. At three separate visits, participants simultaneously completed the PRS-SA survey and several previously validated questionnaires. We constructed a receiver operator characteristics curve for distress levels predicting a Hospital Anxiety and Depression Scale (HADS) score ≥15. We evaluated construct validity for symptom items by comparing severity to the EORTC Core Quality of Life Questionnaire (QLQ-C30) summary score (Pearson correlation tests) and ECOG performance status (Mann–Whitney U tests). We assessed symptom item responsiveness by comparing change in severity to change in QLQ-C30 summary score and comparing standardized mean scores with negative, no, or positive change on the Global Impression of Change (GIC) questionnaire (Jockheere–Terpstra trend test). Overall, 196 participants with solid tumors completed instruments. A distress score of 4 had 82% sensitivity and 55% specificity for clinical depression/anxiety. All symptom items showed construct validity by association with either QLQ-C30 score or performance status (highest p = 0.03). All but cough showed responsiveness to change in QLQ-C30 score (highest p = 0.045). In South African cancer patients, the PRS-SA’s stress scale behaves similarly to the distress thermometer in other populations, and the symptom items demonstrated construct validity and responsiveness. Of note, 46% and 74% of participants who completed the PRS-SA in English or isiZulu, respectively, required assistance reading half or more of the instrument.

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