Diagnostic Efficiency of Single-Photon Emission Computed Tomography with 99MTc-MIBI in Visualization of Malignant Tumors of the Larynx and Laryngopharynx

2015 ◽  
Vol 1084 ◽  
pp. 373-376 ◽  
Author(s):  
Roman Zelchan ◽  
Vladimir Chernov ◽  
Anna Titskaya ◽  
Ivan Sinilkin ◽  
Svetlana Chizhevskaya ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Diagnostic Efficiency ◽  
Single Photon Emission ◽  
Primary Tumors ◽  
Emission Computed ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

To study the diagnostic efficiency of single-photon emission computed tomography (SPECT) with 99mTc-MIBI 40 patients were chosen for diagnosing primary and recurrence of laryngeal or laryngopharyngeal cancer and as well as patients with benign diseases of the larynx. All patients underwent SPECT with 99mTc-MIBI. As a result it has been found that the sensitivity, specificity and accuracy of SPECT with 99mTc-MIBI in the diagnostics of primary tumors of the larynx are 95%, 80% and 92%, respectively. The visualization of recurrent tumors of the larynx and laryngopharynx has showed 100% sensitivity. The obtained results have proved the consistency of SPECT with 99mTc-MIBI as an additional method of diagnostics of <em>laryngeal and laryngopharyngeal</em> cancer.

Diphosphonate single-photon emission computed tomography in cardiac transthyretin amyloidosis

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Aimo ◽  
C Grigoratos ◽  
C Rapezzi ◽  
D Genovesi ◽  
A Barison ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Inferior Wall ◽  
Amyloid Burden ◽  
Single Photon Emission ◽  
Emission Computed ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

Abstract Background Planar diphosphonate scintigraphy is an established diagnostic tool for amyloid transthyretin (ATTR) cardiomyopathy. Characterization of the amyloid burden up to the segmental level by single photon emission computed tomography (SPECT) has not been evaluated so far. Methods Data from consecutive patients undergoing cardiac 99mTc-hydroxymethylene diphosphonate (99mTc-HMDP) SPECT and diagnosed with ATTR cardiomyopathy at a tertiary referral center from June 2016 to April 2019 were collected. Results Thirty-eight patients were included (median age 81 years, 79% men, 92% with wild-type ATTR). In patients with Perugini score 1, the most intense diphosphonate regional uptake was found in septal segments, particularly in infero-septal segments. Among patients scoring 2, the amyloid burden in the septum became more significant, and extended to inferior and apical segments. Finally, patients scoring 3 displayed an intense and widespread tracer uptake. All patients with Perugini score 1 had LGE in at least one antero-septal, one infero-septal, and one infero-lateral segment. All patients with score 2 displayed LGE in infero-septal, inferior, and infero-lateral segments. LGE became extensive in patients scoring 3, with all patients having at least one LGE-positive segment in each region. Conclusions When assimilating different Perugini grades to evolutive stages of the disease, amyloid deposition seem to progress from the septum to the inferior wall and then to the other regions and from the basis to the apex. The potential of segmental analysis might be particularly relevant in patients with very limited cardiac uptake at planar scintigraphy (Perugini score 1). Funding Acknowledgement Type of funding source: None

scholarly journals Single-photon emission computed tomography in a patient with ictal metamorphopsia

Seizure ◽  
2004 ◽  
Vol 13 (4) ◽  
pp. 250-253 ◽  
Author(s):  
KYOUNG HEO ◽  
YANG JE CHO ◽  
SEUNG-KOO LEE ◽  
SUN AH PARK ◽  
KYU-SIK KIM ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Emission Computed ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography
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