Plasma Surface Modification of 316L Stainless Steel for Cardiovascular Stent Coating

2010 ◽  
Vol 89-91 ◽  
pp. 196-201 ◽  
Author(s):  
Enrico Gallino ◽  
Michael Tatoulian ◽  
Farzaneh Arefi-Khonsari ◽  
D. Mantovani

Coronary stents are metallic (316L stainless steel) devices employed during balloon angioplasty to reopen and prevent the re-obstruction of a diseased narrowed area within a coronary artery. To reduce restenosis rate, bare metal stent coating is a promising solution. The coating can act as an anticorrosive barrier against the aggressive properties of biological environment, improving the long-term safety of the device. The goal of this study is to develop a dry process to isolate metallic surface from the biological environment by depositing a thin plasma polymerized allylamine (CH2=CH-CH2-NH2) film on the metallic surface. Plasma polymerized allylamine films were deposited on flat electropolished 316L stainless steel samples in a low pressure plasma reactor (70 kHz). Chemical composition of the coatings has been analysed as a function of the discharge power and treatment time. Moreover, special attention has been paid on the stability of the coating after immersion during 24 hours in D.I. water. Finally, to mimic stent expansion conditions, a “small punch test” has been used to investigate the adhesive properties of the coating. Our results demonstrate that is possible to deposit a stable, cohesive and adhesive plasma polymerized allylamine thin film which can be used as a coating for cardiovascular stents

2008 ◽  
Vol 71 (10) ◽  
pp. 2119-2123 ◽  
Author(s):  
MICHAEL DEILMANN ◽  
HELMUT HALFMANN ◽  
NIKITA BIBINOV ◽  
JOACHIM WUNDERLICH ◽  
PETER AWAKOWICZ

A low-pressure microwave plasma reactor was developed for sterilization of polyethylene terephthalate (PET) bottles. In contrast to the established method using aseptic filling machines based on toxic sterilants, here a microwave plasma is ignited inside a bottle by using a gas mixture of nitrogen, oxygen, and hydrogen. To that effect, a reactor setup was developed based on a Plasmaline antenna allowing for plasma ignition inside three-dimensional packages. A treatment time below 5 s is provided for a reduction of 105 and 104 CFU of Bacillus atrophaeus and Aspergillus niger, respectively, verified by means of a count reduction test. The sterilization results obtained by means of this challenge test are in accordance with requirements for aseptic packaging machines as defined by the U.S. Food and Drug Administration and the German Engineering Federation. The plasma sterilization process developed here for aseptic filling of beverages is a dry process that avoids residues and the use of maximum allowable concentrations of established sterilants, e.g., hydrogen peroxide.


Author(s):  
Gustavo Nuernberg ◽  
Grégori Rosinski ◽  
Priscila Gonçalves ◽  
Marcus Mortean ◽  
Regis Henrique Goncalves e Silva ◽  
...  

2016 ◽  
Vol 58 (6) ◽  
pp. 489-494 ◽  
Author(s):  
Panyasak Phakpeetinan ◽  
Amnuysak Chianpairot ◽  
Ekkarut Viyanit ◽  
Fritz Hartung ◽  
Gobboon Lothongkum

2016 ◽  
Vol 58 (6) ◽  
pp. 547-552 ◽  
Author(s):  
Darko Jagarinec ◽  
Peter Kirbiš ◽  
Jožef Predan ◽  
Tomaž Vuherer ◽  
Nenad Gubeljak

Alloy Digest ◽  
1995 ◽  
Vol 44 (6) ◽  

Abstract BioDur 316LS stainless steel is a modified version of Type 316L stainless steel to improve corrosion resistance for surgical implant applications. The alloy is vacuum arc remelted. This datasheet provides information on composition, physical properties, hardness, and tensile properties. It also includes information on corrosion resistance as well as forming, heat treating, machining, and joining. Filing Code: SS-596. Producer or source: Carpenter.


Alloy Digest ◽  
2015 ◽  
Vol 64 (7) ◽  

Abstract EnduraMet 316LN stainless is a nitrogen strengthened version of Type 316L stainless steel. This datasheet provides information on composition, physical properties, and tensile properties as well as fracture toughness. It also includes information on corrosion resistance as well as forming, heat treating, machining, and joining. Filing Code: SS-1219. Producer or source: Carpenter Technology Corporation.


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