Biomimetic Coating on Zirconia Composites Induced by Chemical Treatment

2007 ◽  
Vol 560 ◽  
pp. 127-132 ◽  
Author(s):  
S. Ortega-Chavarría ◽  
Dora A. Cortés-Hernández ◽  
Akemi A. Nogiwa-Valdez
Keyword(s):  
Calcium Ions ◽  
Chemical Treatment ◽  
Body Fluid ◽  
Apatite Formation ◽  
Biomimetic Coating ◽  
Zirconia Composites ◽  
Alumina Composites ◽  
Simulated Body Fluids ◽  
Biomimetic Method ◽  
Bonelike Apatite

The effect of the chemical treatment of zirconia/alumina composites followed by a biomimetic treatment has been studied. The composites are prepared from a powder mixture of Mg- PSZ and Al2O3. The powders are ball-milled in acetone and uniaxially pressed after drying. The specimens are sintered at 1550 °C in air. After sintering, chemical treatment is performed by immersing the samples in a 5M aqueous solution of phosphoric acid at 95 °C for 4 days. The biomimetic method consists of immersing the chemically-treated samples in simulated body fluid at 36.5 °C. In some cases a wollastonite bed is used as a supplier of calcium ions, resulting in the formation of a bonelike apatite layer. The presence of this bioactive system during the biomimetic process has a positive significant effect on the bioactivation of the composites for either short or long times of immersion of the composites in simulated body fluids. The chemical treatment increases also the rate of apatite formation at short immersion periods.

Apatite Formation on Zirconia Based Composites

2006 ◽  
Vol 309-311 ◽  
pp. 445-448 ◽  
Author(s):  
Dora A. Cortés-Hernández ◽  
Sergio Ortega ◽  
Akemi A. Nogiwa-Valdez
Keyword(s):  
Body Fluids ◽  
Apatite Layer ◽  
Apatite Formation ◽  
Powder Mixtures ◽  
Sintering Mechanism ◽  
Zirconia Composites ◽  
Alumina Composites ◽  
Simulated Body Fluids

Bioactive Mg-PSZ composites were developed by using wollastonite ceramics either as a constituent of the composite formulation or as a bioactive bed during the biomimetic treatment in simulated body fluids. The zirconia composites were prepared by uniaxial pressing of powder mixtures and sintered at 1550oC in air. Wollastonite containing zirconia/alumina composites were also sintered at 1350oC. The composites were immersed in SBF for 7 days on a bed of wollastonite powder and then re-immersed in 1.5SBF for 7 days. Tests were also performed with no wollastonite bed. A highly bioactive surface was observed on the Mg-PSZ/CaSiO3 and Mg-PSZ/Al2O3 composites. A homogeneous apatite layer was detected on the Mg-PSZ/CaSiO3 composites immersed for only 7 days in SBF. No apatite was formed on the Mg-PSZ/Al2O3/CaSiO3 composite. During the sintering mechanism at either 1550 or 1350oC small amounts of aluminosilicate phases are formed. These phases inhibited the apatite formation.

Bioactive Zirconia Composites

2006 ◽  
Vol 509 ◽  
pp. 193-198 ◽  
Author(s):  
Akemi A. Nogiwa-Valdez ◽  
Dora A. Cortés-Hernández ◽  
J.M. Almanza-Robles ◽  
Alejandra Chávez-Valdez
Keyword(s):  
Calcium Ion ◽  
Body Fluids ◽  
Apatite Layer ◽  
Powder Bed ◽  
Sio2 Glass ◽  
Zirconia Composites ◽  
Alumina Composites ◽  
Simulated Body Fluids ◽  
Concentrated Solution ◽  
Bonelike Apatite

Zirconia-alumina composites with additions of a CaO-SiO2 glass are prepared by uniaxial pressing and sintering. In order to promote bioactivity, the composites are biomimetically treated. The effect of immersion time in simulated body fluids (SBF) and that of the presence of a wollastonite powder bed, as a calcium ion provider, on the apatite forming ability are investigated. The influence of replacing the simulated body fluids each 7-day-period for a more concentrated solution is also studied. A bonelike apatite layer is observed after 21 days of immersion when the SBF is renewed, whether the bed of wollastonite powder is present or not. However, a thicker layer is formed by using wollastonite and the agglomerates of the apatite layer are finer on the composites containing CaO-SiO2 glass.

Comparison of Apatite Formation on Polyamide Films Containing Carboxyl and Sulfonic Groups in a Solution Mimicking Body Fluid

2006 ◽  
Vol 309-311 ◽  
pp. 477-480
Author(s):  
Chikara Ohtsuki ◽  
Takahiro Kawai ◽  
Masanobu Kamitakahara ◽  
Masao Tanihara ◽  
Toshiki Miyazaki ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Crystal Growth ◽  
Simulated Body Fluid ◽  
Calcium Ions ◽  
Body Fluid ◽  
Functional Group ◽  
Carboxyl Groups ◽  
Apatite Formation ◽  
Ion Concentrations ◽  
Polyamide Film

Apatite formation on polyamide films containing either carboxyl or sulfonic groups was compared in 1.5SBF, whose ion concentrations are 1.5 times those of a simulated body fluid (SBF). The sulfonic groups induced the apatite nucleation earlier than the carboxyl groups. In contrast, the rate of crystal growth depended not on the kind of functional group, but on the degree of supersaturation of the surrounding solution. The more ready association of sulfonic groups with calcium ions may lead to earlier apatite nucleation than that of carboxyl groups. Adhesive strength of the apatite layer to polyamide film containing sulfonic groups was significantly lower than that with carboxyl groups depending on the chemical interactions as well as on the mechanical properties of the polyamide film.

Bonelike Apatite Formation on Anodically Oxidized Titanium Metal in Simulated Body Fluid

2003 ◽  
Vol 254-256 ◽  
pp. 459-462 ◽  
Author(s):  
Kawashita Masakazu ◽  
Xin-Yu Cui ◽  
Hyun Min Kim ◽  
Tadashi Kokubo ◽  
Takashi Nakamura
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Apatite Formation ◽  
Titanium Metal ◽  
Bonelike Apatite

scholarly journals Apatite-Forming Ability of Flowable vs. Putty Formulations of Newly Developed Bioactive Glass-Containing Endodontic Cement

2021 ◽  
Vol 11 (19) ◽  
pp. 8969
Author(s):  
Naoki Edanami ◽  
Razi Saifullah Ibn Belal ◽  
Shoji Takenaka ◽  
Kunihiko Yoshiba ◽  
Nagako Yoshiba ◽  
...  
Keyword(s):  
Calcium Ions ◽  
Calcium Ion ◽  
Body Fluid ◽  
Apatite Formation ◽  
Ion Release ◽  
Phosphate Ion ◽  
Phosphate Ions ◽  
Ability Levels ◽  
Consumption Rates ◽  
The Media

This study compared the apatite-forming ability (AFA) levels of flowable and putty formulations of Nishika Canal Sealer BG Multi (F-NBG and P-NBG, respectively) and attempted to clarify the cause of differences in the AFA levels of F-NBG and P-NBG. NBG samples were aged in simulated body fluid (SBF) or 1-, 5-, or 10-g/L bovine serum albumin-containing SBF (BSA-SBF) and analyzed in terms of their ultrastructures, elemental compositions, and Raman spectra to identify apatite formation. The phosphate ion consumption rates of NBG samples in the media were evaluated as an indicator of apatite growth. The original elemental composition, calcium ion release, and alkalizing ability levels of F-NBG and P-NBG were also evaluated. Apparent apatite formation was detected on all NBG samples except F-NBG aged in 10-g/L BSA-SBF. P-NBG consumed phosphate ions faster than F-NBG. As-prepared P-NBG showed more silicon elements on its surface than as-prepared F-NBG. P-NBG released more calcium ions than F-NBG, although their alkalizing ability levels did not differ statistically. In conclusion, the AFA of P-NBG was greater than that of F-NBG, probably because of the greater ability of P-NBG to expose silanol groups on the surface and release calcium ions.

Use of Wollastonite in a Biomimetic Method to Promote Apatite Formation on a Co-Cr-Mo Alloy

2005 ◽  
Vol 284-286 ◽  
pp. 239-242 ◽  
Author(s):  
Dora A. Cortés-Hernández ◽  
A. Medina Ramírez ◽  
José C. Escobedo-Bocardo ◽  
M.A. López ◽  
J.M. Almanza-Robles
Keyword(s):  
Aqueous Solution ◽  
Apatite Layer ◽  
Apatite Formation ◽  
Chemically Treated ◽  
Biomimetic Method ◽  
Bonelike Apatite

Wollastonite ceramics was used in a biomimetic method to promote apatite formation on a Co-Cr-Mo alloy (ASTM F-75). The metallic samples were initially chemically treated in a 5M NaOH aqueous solution. The treated samples were immersed for 7 days in SBF on a bed of wollastonite and then immersed 7 or 14 days in 1.5SBF. For comparative purposes no wollastonite was used during the first 7 days in some tests. A homogeneous bonelike apatite layer was formed on the samples immersed in SBF on the wollastonite bed. The morphology and the Ca/P ratio of the layer were closely similar to those observed on the existing bioactive systems. A thinner homogeneous bonelike apatite layer was formed on the samples immersed in SBF and 1.5SBF without using wollastonite. However, the morphology and the Ca/P ratio of this layer differs slightly to that observed on the existing bioactive systems. The immersion of the samples during the first days in SBF on a wollastonite bed improves significantly the quality and thickness of the bonelike apatite layer.

Bonelike Apatite Formation Induced on Zirconia Gel in a Simulated Body Fluid and Its Modified Solutions

2004 ◽  
Vol 84 (9) ◽  
pp. 2041-2044 ◽  
Author(s):  
Masaki Uchida ◽  
Hyun-Min Kim ◽  
Tadashi Kokubo ◽  
Fumiaki Miyaji ◽  
Takashi Nakamura
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Apatite Formation ◽  
Bonelike Apatite

scholarly journals Apatite Formation on Electrochemically Treated Titanium

1999 ◽  
Vol 599 ◽  
Author(s):  
K. Tsuru ◽  
S. Takemoto ◽  
S. Hayakawa ◽  
A. Osaka
Keyword(s):  
Calcium Ions ◽  
Body Fluid ◽  
Cathodic Polarization ◽  
Apatite Formation ◽  
Hydrated Silica ◽  
Spontaneous Deposition ◽  
Artificial Materials ◽  
Titania Gel ◽  
A Cell ◽  
Harmful Effects

AbstractApatite formation on artificial materials in a body environment is the prerequisite condition for showing bioactivity i.e. bone-bonding ability. A specific hydrated silica or titania gel has the ability of apatite deposition in body environment. We electrochemically prepared such a bioactive titanium oxide layer on titanium(Ti) with a cell consisting of Ti as the working electrode, Pt as the counter one, Ag/AgCl as the reference one, and an aqueous solution of 0.1 mol/L Ca(NO3)2 as the electrolyte solution. Ti was kept at 9.5V for 1 hour for oxidation(denoted as Ca9.5). Ti was subject to cathodic polarization at −3.0V for 10 min(Ca-3.0).: calcium ions were expected to be adsorbed on its surface. On treatment Ca9.5–3.0 Ti was first oxidated at 9.5V for 1 hour and subsequently kept at −3.0V for 10 min. The specimens of Ca9.5–3.0 and Ca-3.0 were found so bioactive as to deposit apatite within 12 hours and 1 day, respectively, in a simulated body fluid(Kokubo solution) whereas those due to Ca9.5 could not deposit apatite within 7 days. Calcium hydroxide and calcium carbonate detected on the bioactive surface caused no harmful effects on spontaneous deposition of apatite in the fluid.

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