Fabrication and Biological Properties of Bionic Structure Porous Alumina Ceramics with Spherical/Lamellar Pores

2015 ◽  
Vol 815 ◽  
pp. 367-372 ◽  
Author(s):  
Yu Fei Tang ◽  
Qian Miao ◽  
Ying Liu ◽  
Zi Xiang Wu ◽  
Wei Zhang ◽  
...  

In order to solve the problem that low pore connectivity of the spherical porous ceramic, bionic structure porous alumina ceramics with spherical/lamellar pores were fabricated combining the adding pore-forming agent and two step freeze casting. The effects of fabrication parameters of the samples on morphologies, porosity and pore connectivity are investigated. The mechanical and biological properties of bionic structure porous alumina ceramics are also characterized. Results show that porous alumina ceramics with spherical/lamellar pores are obtained, and the lamellar pores pass through the spherical pores, which prove the pore connectivity reach 86.2 %. The mechanical properties are improved by porosity gradient from the inside (highly porous) to the outside (less porous) of porous alumina. Bionic structure porous alumina ceramics with spherical/lamellar pores have better cell growth and absorbance than those with spherical or lamellar pores only since its high pore connectivity.

Author(s):  
Mansure Kazemi ◽  
Bahareh Nazari ◽  
Jafar Ai ◽  
Nasrin Lotfibakhshaiesh ◽  
Ali Samadikuchaksaraei ◽  
...  

Recent advances in the field of biomaterials have led to the development of ceramic–matrix nanocomposites with enhanced mechanical properties, which is essential for hard tissue scaffolds. In this study, the improvement in mechanical and biological properties of β-tricalcium phosphate reinforced with 45S5 bioactive glass under different sintering conditions was studied. In order to improve the thermal stability and biological responses, β-tricalcium phosphate was doped with 5 mol% strontium ions. Highly porous nanocomposites, with different weight ratios of Sr-tricalcium phosphate/bioactive glass (75/25, 50/50, 25/75), were fabricated through the foam replication method by sintering samples under various thermal conditions (1200–1250 ℃/0–1 h). The effects of bioactive glass content and sintering parameters on microstructure and mechanical behaviors of the nanocomposites were assessed. The obtained results showed that increasing 45S5 bioactive glass content, sintering temperature, and dwelling time gradually improved the mechanical properties of final products which were ascribed to the improved ceramic densification. The composites with the optimal compressive strength were selected to apply in further characterization and cell culture experiments. The selected scaffolds showed excellent bioactivity since a continuous layer of minerals covered the entire surface of composites after immersion in simulated body fluid solution for two weeks. Moreover, the cell culture studies demonstrated that the composite scaffolds could well support the attachment and proliferation of MG-63 osteoblast-like cells. This investigation clearly concluded that the appropriate incorporation of 45S5 bioactive glass into the β-tricalcium phosphate matrix can effectively promote the mechanical behavior, bioactivity, and biocompatibility of the resultant composite scaffolds.


Cerâmica ◽  
2019 ◽  
Vol 65 (suppl 1) ◽  
pp. 70-74 ◽  
Author(s):  
G. C. Ribeiro ◽  
B. A. Fortes ◽  
L. da Silva ◽  
J. A. Castro ◽  
S. Ribeiro

2016 ◽  
Vol 42 (7) ◽  
pp. 8478-8487 ◽  
Author(s):  
Carolina Tallon ◽  
Chayuda Chuanuwatanakul ◽  
David E. Dunstan ◽  
George V. Franks

2012 ◽  
Vol 2012 ◽  
pp. 1-6
Author(s):  
Eun-Hee Kim ◽  
Yeon-Gil Jung ◽  
Chang-Yong Jo

Prepolymer, which can be polymerized by a photo, has been infiltrated into a porous ceramic to improve the addition effect of polymer into the ceramic, as a function of the functionality of prepolymer. It induces the increase in the mechanical properties of the ceramic. The porous alumina (Al2O3) and the polyurethane acrylate (PUA) with a network structure by photo-polymerization were used as the matrix and infiltration materials, respectively. The porous Al2O3matrix without the polymer shows lower values in fracture strength than the composites, since the stress is transmitted more quickly via propagation of cracks from intrinsic defects in the porous matrix. However, in the case of composites, the distribution of stress between heterophases results in the improved mechanical properties. In addition, the mechanical properties of composites, such as elastic modulus and fracture strength, are enhanced with increasing the functionality of prepolymer attributed to the crosslinking density of polymer.


2014 ◽  
Vol 926-930 ◽  
pp. 186-189
Author(s):  
Xian Zhong Wang

The preparation process of porous alumina ceramics, the effect of process parameters on the performance of porous ceramic, the findings suggest that pore-forming agent sintered alumina ceramics sintered strength properties and have a greater impact; binders for ceramic porous A1203 porosity has a greater impact.


2018 ◽  
Vol 44 (11) ◽  
pp. 13240-13246 ◽  
Author(s):  
Jingjing Liu ◽  
Bo Ren ◽  
Tianbin Zhu ◽  
Shu Yan ◽  
Xiaoyan Zhang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document