Subtraction Ictal SPECT Coregistered to MRI for Seizure Focus Localization in Partial Epilepsy

2000 ◽  
Vol 75 (6) ◽  
pp. 615-624 ◽  
Author(s):  
Benjamin H. Brinkmann ◽  
Terence J. O'Brien ◽  
Brian P. Mullan ◽  
Michael K. O'Connor ◽  
Richard A. Robb ◽  
...  
Keyword(s):  
Partial Epilepsy ◽  
Ictal Spect ◽  
Seizure Focus ◽  
Focus Localization

scholarly journals Automatic and Remote Controlled Ictal SPECT Injection for Seizure Focus Localization by Use of a Commercial Contrast Agent Application Pump

Epilepsia ◽  
2007 ◽  
Vol 48 (7) ◽  
pp. 1409-1413 ◽  
Author(s):  
Michael Feichtinger ◽  
Hans Eder ◽  
Alexander Holl ◽  
Eva Körner ◽  
Gerda Zmugg ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Ictal Spect ◽  
Seizure Focus ◽  
Focus Localization

scholarly journals The appropriacy of fluency tests in assessing epileptic seizure lateralization in children with partial epilepsy

Psihologija ◽  
2008 ◽  
Vol 41 (2) ◽  
pp. 195-211
Author(s):  
Jasmina Vuksanovic ◽  
Milena Djuric
Keyword(s):  
Left Hemisphere ◽  
Right Hemisphere ◽  
Partial Epilepsy ◽  
Quantitative Comparison ◽  
Control Group ◽  
Healthy Children ◽  
Healthy Controls ◽  
Seizure Focus ◽  
Qualitative And Quantitative ◽  
The Right

Fluency tests are frequently used in clinical practice to asses executive functions. The literature data are not unequivocal although in a great number of papers is pointed out the importance of the left hemisphere, specially of the left frontal lobes in the mediation of phonological fluency and the right hemisphere in the mediation of nonverbal fluency. This paper considers the suitability of fluency tests for the detection of left versus right seizure laterality. The sample consisted of thirty-two epilepsy patients divided into two groups: LHF-participants with the seizure focus in the left hemisphere (n=16), and DHF-participants with the seizure focus in the right hemisphere (n=16), and K-the control group of t age-matched healthy children (n=50) aged 7-11 years. The qualitative and quantitative comparison of the phonological and nonverbal fluency performance was carried out in consideration of the seizure laterality as well as compared to the healthy controls. The results of phonological fluency performance revealed that the performance of the LHF group was significantly reduced as compared to both DHF and K group. The analysis of nonverbal fluency performance revealed that the performance of the DHF group was significantly reduced as compared to both LHF and K group The qualitative analysis obtained valuable data, which could additionally contribute to the neuropsychological evaluation of the left versus right seizure laterality.

How to Inject Ictal SPECT? From Manual to Automated Injection

2021 ◽  
Author(s):  
Xavier Setoain ◽  
Francisco Campos ◽  
Antonio Donaire ◽  
Maria Mayoral ◽  
Andres Perissinotti ◽  
...  
Keyword(s):  
Injection System ◽  
Control Group ◽  
Epileptogenic Zone ◽  
Drug Resistant ◽  
Injection Time ◽  
Tracer Injection ◽  
Ictal Spect ◽  
Seizure Focus ◽  
Drug Resistant Epilepsy ◽  
Automated Injection

Abstract BackgroundSuccessful surgery depends on the accurate localization of epileptogenic zone before surgery. Ictal SPECT is the only imaging modality that allows identification of the ictal onset zone by measuring the regional cerebral blood flow at the time of injection. The main limitations of ictal SPECT in epilepsy are the complex methodology of the tracer injection during a seizure. To overcome these limitations, we present the main features of the first automated injector for ictal SPECT (epijet, LemerPax; La Chapelle -sur-Erdre; France). In this study we compared traditional manual injection with automated injection for ictal SPECT in122 patients with drug-resistant epilepsy. MethodsThe study included 55 consecutive prospective patients with drug-resistant epilepsy undergoing injection with the automated injector. The control group was our retrospective database of a historic pool of 67 patients, injected manually from 2014-2016. Calculated annual exposure/radioactive dose for operators was measured. Injection time, seizure focus localization with ictal SPECT, as well as repeated hospitalizations related to fails injections were compared in these two groups of patients. ResultsThere were no differences in the average injection time with epijet (13 s) compared with the traditional manual injection (14s). The seizure focus was successfully localized with ictal SPECT with epijet in 44/55 (80%) patients and with manual injection in 46/67 (68%) patients (p=0.694). Repeated studies were required in 16/67 (23%) patients in the manual injection group compared to 4 patients (7%) in the epijet group (p=0.022). Calculated annual exposure/dose for operators of 0.39 mSv/year and administered dose error inferior to 5% are other advantages of epijet. ConclusionThe first results using epijet are promising in adjustment of the injection dose, reducing the rate of radiation exposure for patients and nurses, maintaining the same injection time and allowing high SPECT accuracy. These preliminary results support the use of an automated injection system to inject radioactive ictal SPECT doses in epilepsy units.

Ictal SPECT in children with partial epilepsy due to focal cortical dysplasia

2004 ◽  
Vol 31 (2) ◽  
pp. 89-95 ◽  
Author(s):  
Ajay Gupta ◽  
Shankar Raja ◽  
Prakash Kotagal ◽  
Deepak Lachhwani ◽  
Elaine Wyllie ◽  
...  
Keyword(s):  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Partial Epilepsy ◽  
Ictal Spect

The Practical Utility of Performing Peri-Ictal SPECT in the Evaluation of Children With Partial Epilepsy

1998 ◽  
Vol 19 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Terence J. O’Brien ◽  
Mary L. Zupanc ◽  
Brian P. Mullan ◽  
Michael K. O’Connor ◽  
Benjamin H. Brinkmann ◽  
...  
Keyword(s):  
Partial Epilepsy ◽  
Ictal Spect ◽  
Practical Utility

An interactive interface for seizure focus localization using SPECT image analysis

2006 ◽  
Vol 36 (1) ◽  
pp. 70-88 ◽  
Author(s):  
Mark Rossman ◽  
Malek Adjouadi ◽  
Melvin Ayala ◽  
Ilker Yaylali
Keyword(s):  
Image Analysis ◽  
Seizure Focus ◽  
Interactive Interface ◽  
Spect Image ◽  
Focus Localization

Subdural electrode recordings for seizure focus localization

1989 ◽  
Vol 2 (3) ◽  
pp. 129-135 ◽  
Author(s):  
Thomas Jay Rosenbaum ◽  
Kenneth D. Laxer
Keyword(s):  
Seizure Focus ◽  
Subdural Electrode ◽  
Focus Localization

Subdural Electrodes for Seizure Focus Localization

Neurosurgery ◽  
1986 ◽  
Vol 19 (1) ◽  
pp. 73-81 ◽  
Author(s):  
Thomas J. Rosenbaum ◽  
Kenneth D. Laxer ◽  
Michael Vessely ◽  
W. Brewster Smith
Keyword(s):  
Electrode Placement ◽  
Surgical Decision ◽  
Electrode Implantation ◽  
Seizure Focus ◽  
Seizure Disorders ◽  
Depth Electrodes ◽  
Subdural Electrode ◽  
Focus Localization ◽  
Significant Addition ◽  
Made In

Abstract Fifty patients with medically refractory partial seizure disorders have undergone subdural electrode placement for seizure focus localization. Standard scalp telemetry recordings of ictal events had failed to demonstrate accurately the site of seizure onset, and these patients were considered candidates for telemetry with intracerebral depth electrodes. Excellent recordings of interictal and ictal events were obtained, and localization of the epileptogenic focus was derived from recordings made during spontaneously occurring seizures. Electrocorticograms were monitored for up to 21 days. The recordings enabled a surgical decision to be made in 43 of 50 cases (86%). Thirty patients have subsequently undergone cortical excision of their foci with good results. Subdural electrode recordings are a significant addition to the armamentarium of the neurosurgeon attempting to localize surgical seizure foci, offering a low morbidity procedure as an alternative to depth electrode implantation.

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