scholarly journals Unusual case of locally advanced and metastatic paratesticular liposarcoma: a case report and review of the literature

2015 ◽  
Vol 87 (1) ◽  
pp. 87 ◽  
Author(s):  
Stefano Chiodini ◽  
Lorenzo G. Luciani ◽  
Tommaso Cai ◽  
Alberto Molinari ◽  
Luca Morelli ◽  
...  

Liposarcoma accounts for 20% of all sarcomas and is a rare occurrence in the paratesticular region. We present the case of a 66-year-old man with a massive liposarcoma of the right scrotum invading the lower limb and the abdominal wall skin. The case concerns an unusually large and aggressive liposarcoma (25 cm), presenting with multiple lung and nodal metastases. The patient had an unfavourable evolution with rapid progression of metastases, although there were no signs of local disease. In this case, a wide local excision was performed in order to obtain local control of the disease. Even though paratesticular sarcomas might have a more favourable evolution, the association with lung involvement carries an ominous prognosis. Diagnosis of paratesticular sarcoma should be kept in mind in case of irregular necrotic masses in the inguinal and scrotal region.

2008 ◽  
Vol 132 (10) ◽  
pp. 1672-1674
Author(s):  
Seethalakshmi Viswanathan ◽  
Sangeeta B. Desai ◽  
S. R. Prabhu ◽  
Mahul B. Amin

Abstract We describe an extremely rare occurrence of a squamous differentiation in a sarcomatoid chromophobe renal cell carcinoma in a 45-year-old woman with nodal and lung metastasis at presentation. The tumor on histology showed all 3 components intimately admixed with each other, which to the best of our knowledge is the first such case to be reported in the literature. The renal pelvis was smooth walled and uninvolved. Kidney-specific cadherin was positive in the chromophobe renal cell carcinoma areas and negative in the sarcomatoid and squamous areas.


2004 ◽  
Vol 128 (12) ◽  
pp. 1432-1434 ◽  
Author(s):  
Whitney A. High ◽  
Matthew J. Larson ◽  
Mai P. Hoang

Abstract Petrification of the auricle results in a rigid and immalleable ear. The etiology of such a finding is usually ectopic calcification. The condition has been associated with injurious processes, such as cold injury, and with various endocrinopathies, including Addison disease. In a significant number of cases, ossification occurs without knowledge of the precipitating cause or event. True auricular ossification is a rare occurrence, with only 12 histologically confirmed cases in the literature. We herein present the clinical and pathologic findings of another case. A 60-year-old man with diet-controlled diabetes presented with a 10-year history of slowly and insidiously stiffened auricles. He denied any precipitating historical events. Routine testing did not demonstrate systemic abnormalities. Radiographic examination revealed opacities consistent with bony structure in the auricles of the ears, with the right more prominent than the left. Histologic sampling demonstrated ossification with deposition of trabecular bone in proximity to normal elastic cartilage.


2018 ◽  
Vol 7 (12) ◽  
pp. 205846011880632
Author(s):  
Dolores Ferrara ◽  
Gianfranco Vallone ◽  
Enrico Tedeschi ◽  
Andrea Ponsiglione ◽  
Arnaldo Stanzione ◽  
...  

Tuberous sclerosis (TS) is a relatively rare multi-organ disorder generally diagnosed in infancy and described as a clinical triad of sebaceous adenoma, mental retardation, and seizures. Angiomyolipoma (AML) is the most common benign renal tumor usually found incidentally as a solitary small echogenic lesion on grayscale ultrasound. Less commonly, it is part of the TS complex and is seen as multiple lesions in both kidneys. We describe an unusual case of TS incidentally diagnosed in a 37-year-old female patient with several and bilateral renal AMLs and a single cortical–subcortical tuber in the right parieto-occipital cerebral lobe.


2018 ◽  
Vol 6 ◽  
pp. 2050313X1877530 ◽  
Author(s):  
Henrik Holtmann ◽  
Thomas Böttinger ◽  
Norbert R Kübler ◽  
Daman D Singh ◽  
Christoph K Sproll ◽  
...  

Synovial chondromatosis is a benign disease which most commonly appears in large joints and only rarely affects the temporomandibular joint. The diagnosis is quite difficult due to the fact that a large swelling in the preauricular area and the radiographic findings may be misdiagnosed as other benign or malignant diseases. We report an unusual case of intra- and extracapsular chondromatosis of 25 osteochondral loose bodies in the right temporomandibular joint.


2020 ◽  
Vol 6 (4) ◽  
pp. 20200080
Author(s):  
Avinash D Gautam ◽  
Shweta Jain ◽  
M Ravi Sankar ◽  
Neeraj Jain

We are reporting a case of a 47-year-old male with primary synovial sarcoma of the right parotid gland with tumor thrombus extension in the right internal jugular vein and right atrium. The rarity of this occurrence as documented in the review of the literature provides for uncertainty about proper management. Our case represents a rare occurrence with the unique radiological finding that has implications for management.


2014 ◽  
Vol 8 (7-8) ◽  
pp. 545 ◽  
Author(s):  
Biao Dong ◽  
Yuantao Wang ◽  
Jianjian Zhang ◽  
Yaowen Fu ◽  
Gang Wang

Multilocular cystic nephroma is a relatively rare benign tumour of the kidney, which usually presents as a unilateral multicystic renal mass without solid elements. The lesions typically have a bimodal age, with peak incidence in male children under 24 months and another one in women over 40 old. We present an unusual case report of multilocular cystic nephroma in the right kidney in a 30-year-old male. Laparoscopic partial nephrectomy was performed. The pathologic examination confirmed a multilocular cystic nephroma in the right renal specimens. We present the image findings, pathological features, treatment alternatives and a review of the literature.


2021 ◽  
Vol 14 (12) ◽  
pp. e246797
Author(s):  
Matilde Matos Martins ◽  
Patrícia Ferreira ◽  
Raquel Maciel ◽  
Cristina Costa

A 26-year-old woman under immunosuppression with infliximab due to Crohn’s disease was referred to the gynaecology emergency room with dispersed and coalescing vesicular lesions on the vulvar region extending to the right lower limb involving S2–S3 dermatome, associated with severe pain. Clinical history, physical examination and serological testing was consistent with herpes zoster infection. The patient was treated with valaciclovir for 14 days and cefradine for 7 days (due to the possibility of secondary bacterial infection). Significant symptomatic improvement was noted after 1 week. The 1-year follow-up was unremarkable. According to our knowledge and review of the literature, this is one of the few cases reported of vulvar herpes zoster, especially related to infliximab.


2019 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Brenna L. Hennessey ◽  
Logan S. Schwarzman ◽  
Dorotea Mutabdzic ◽  
Sameer A. Patel ◽  
Anthony J. Olszanski ◽  
...  

VASA ◽  
2020 ◽  
pp. 1-6 ◽  
Author(s):  
Marina Di Pilla ◽  
Stefano Barco ◽  
Clara Sacco ◽  
Giovanni Barosi ◽  
Corrado Lodigiani

Summary: A 49-year-old man was diagnosed with pre-fibrotic myelofibrosis after acute left lower-limb ischemia requiring amputation and portal vein thrombosis. After surgery he developed heparin-induced thrombocytopenia (HIT) with venous thromboembolism, successfully treated with argatroban followed by dabigatran. Our systematic review of the literature supports the use of dabigatran for suspected HIT.


2015 ◽  
Vol 24 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Jan Ulrych ◽  
Vladimir Fryba ◽  
Helena Skalova ◽  
Zdenek Krska ◽  
Tomas Krechler ◽  
...  

Heterotopic pancreas is a congenital pathology of the gastrointestinal tract, particularly rare in the esophagus. Both symptomatology and findings during preoperative examinations are non-specific and therefore do not often lead to an accurate diagnosis, which is usually revealed only by histopathological assessment of a resected specimen. We report an unusual case of a patient suffering from severe dysphagia caused by heterotopic pancreas in the distal esophagus with chronic inflammation and foci of premalignant changes. This article also reviews 14 adult cases of heterotopic pancreas in the esophagus previously reported in the literature, with the aim of determining the clinical features of this disease and possible complications including rare premalignant lesions and malignant transformation. Especially with regard to those complications, we suggest that both symptomatic and incidentally found asymptomatic lesions should be resected.


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