scholarly journals Next-generation nutritional biomarkers to guide better health care

2016 ◽  
Vol 60 (2) ◽  
Author(s):  
CarloAlberto Redi

One of the main precision medicine’s promises is nutrigenomics; still far from being a widespread attitude for the laypeople, it is certainly one of the most challenging aspect of the near to come health care system based on personalized medicine. Thus, we welcome books like this one that is exploring the pre-requisites to get a better health care in the new millennium.....

Author(s):  
Subhas C. Misra ◽  
Sandip Bisui ◽  
Kamel Fantazy

Among the emerging areas in health-care system, the implementation of Electronic Medical Record system and the discovery of Personalized Medicine are occupying top positions. While some of the personalized drugs have already been discovered, implementing this new medicare system requires a lot of changes in the traditional health-care system. This paper aims at identifying these critical changes required in the adoption of the Personalized Medicine system. A systemic attempt has been made to prepare a list of possible changes required for the adoption based on available literature. This research study shows that changes from reactive to efficient medical care, from trial and error to right treatment for right person at right time, from narrow mind-set to open mindedness, from open information of patients to secure information, from less emphasis on IT infrastructure to more emphasis on IT infrastructure are some of the significant changes that are necessary for implementing the revolutionary medicare system of personalized Medicine.


2016 ◽  
Vol 6 (3) ◽  
pp. 18 ◽  
Author(s):  
Scott Weiss

Recently we at Partners Health Care had a series of articles in the Journal of Personalized Medicine describing how we are going about implementing Personalized Medicine in an academic health care system [1–10].[...]


Stroke ◽  
2021 ◽  
Author(s):  
Emma Reford ◽  
Christopher P. Kellner

Stroke and COVID-19 are both traumatic and life-altering experiences that are marked by uncertainty, fear, and medical intervention. The devastation that stroke and COVID-19 oppress on an individual and a population is well established, and these traumas are potently magnified in the troughs of the COVID-19 pandemic. Furthermore, stroke has been shown to be a potential complication of COVID-19 infection, and while there is global controversy regarding this finding, it is undeniable that there are patients across the world presenting with both conditions concurrently. Thus, the topic of isolated stroke and the co-occurrence of stroke and COVID-19 amidst the pandemic both warrant considerable investigation on both a basic science level and a humanistic level. This opinion article advocates for a narrative medicine approach to better explicate the intertwining of stroke and COVID-19. Interviewing patients who presented with both stroke and COVID-19 as well as patients who present with stroke during the pandemic will provide the opportunity to gather and juxtapose individual illness experiences, including encounters with the health care system, relationship with care teams and care takers, recovery, and insights into the future. Creating, analyzing, and comparing such an anthology of illness narratives of the 2 patient populations will offer a unique understanding into the experience of different, yet over-lapping, medical traumas in an unprecedented time. With this deeper appreciation of patient accounts, the health care system can better recognize how to provide for future patients who present specifically with stroke or stroke and COVID-19. However, more broadly, this study can also afford insight into how the health care system can better provide for and support patients who present with complex diagnoses in the context of a complex healthcare system, which most probably will operate under the effects of the pandemic for time to come as well as other, future complicating factors.


2020 ◽  
pp. 43-47
Author(s):  
V. Grinchenko ◽  
S. Skakun ◽  
S. Chudakov

The article reveals a strategically important topic at the present stage — the new role of patients in the emerging system of personalized preventive medicine in the world and in our country. The transition of patients to a proactive position based on the need for conscious management of their own health, the formation of new personal competencies and new principles of interaction with the doctor and the health care system as a whole is justified.


Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1121
Author(s):  
Chiaki Inagaki ◽  
Daichi Maeda ◽  
Kazue Hatake ◽  
Yuki Sato ◽  
Kae Hashimoto ◽  
...  

Next-generation sequencing (NGS) assay is part of routine care in Japan owing to its reimbursement by Japan’s universal health-care system; however, reimbursement is limited to patients who finished standard treatment. We retrospectively investigated 221 patients who underwent Foundation One CDX (F1CDx) at our hospital. Every F1CDx result was assessed at the molecular tumor board (MTB) for treatment recommendation. Based on patients’ preferences, presumed germline findings were also assessed at the MTB and disclosed at the clinic. In total, 204 patients underwent F1CDx and 195 patients completed the analysis; however, 13.8% of them could not receive the report due to disease progression. Among 168 patients who received the results, 41.6% had at least one actionable alteration, and 3.6% received genomically matched treatment. Presumed germline findings were nominated in 24 patients, and 16.7% of them contacted a geneticist counselor. The NGS assay should be performed earlier in the clinical course to maximize the clinical benefit. Broader reimbursement for the NGS assay would enhance the delivery of precision oncology to patients. Access to clinical trials affects the number of patients who benefit from NGS. Additionally, the disclosure of presumed germline findings is feasible in clinical practice.


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